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Oxidative stress response in children undergoing cardiac surgery: Utility of the clearance of isoprostanes

Abstract Introduction Cardiac surgery (CS) in pediatric patients induces an overt oxidative stress (OS) response. Children are particularly vulnerable to OS related injury. The immaturity of their organs and antioxidant..

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A Trip to the Moon: Neonatal ABO Non-Compatible Heart Transplant in Donor Circulatory Death

Donation after Circulatory Death (DCD) is gaining worldwide acceptance as an adjunct to brain death (BD) in transplant surgery. Initially performed for abdominal organs procurement, DCD was then carried out..

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Extracorporeal Membrane Oxygenation for Pediatric Toxin Exposures

Abstract Evidence for the use of extracorporeal membrane oxygenation (ECMO) in children with refractory respiratory failure or shock following ingestion or toxin exposure, has been confined to single-center experiences, individual..

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Recombinant Factor VIIa in pediatric cardiac surgery

Abstract Objectives Recombinant factor VIIa is used off-label for refractory bleeding after cardiac surgery. This study reviewed the indications, usage rates and complications of recombinant factor VIIa. Design Retrospective case..

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Hemadsorption as a treatment option for Multisystem Inflammatory Syndrome in Children associated with COVID-19. A case report.

This case reports on a 17-year-old male patient with a history of fever, dyspnea, diffuse chest and abdominal pain, and generalized rash following COVID-19 molecular diagnosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/08/CoW_31_2021_E_web_compressed.pdf"]  

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Multisite Veno-Venous Cannulation for Neonates and Nonambulatory Children

Abstract OBJECTIVES:  Neonates with respiratory failure are ideally supported with veno-venous rather than veno-arterial extracorporeal membrane oxygenation due to the reduced rate of neurologic complications. However, the proportion of neonates..

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Extracorporeal Life Support Organization (ELSO) Guidelines for Follow-up After Neonatal and Pediatric Extracorporeal Membrane Oxygenation

Abstract Neonates and children who have survived critical illness severe enough to require extracorporeal membrane oxygenation (ECMO) are at risk for neurologic insults, neurodevelopmental delays, worsening of underlying medical conditions,..

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Association of perfusate oxygenation with cardiovascular disorder in tetralogy of fallot children: A nested case–control study

Abstract Background Little is known regarding whether hyperoxic reoxygenation was associated with higher risk of cardiovascular disorder following tetralogy of Fallot repair. Methods We performed a nested case–control study among..

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Tricuspid valve bacterial endocarditis and vegetation in pediatric population

Patient with tricuspid valve bacterial endocarditis and vegetation in pediatric population. Beating on pump total inflow. [gallery ids="17859,17868,17865,17862,17856,17853"] Dr.Sam Zeraatian Nejad Davani, CEO of rockingham medical research ADKWA center as..

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The Albumin-to-Fibrinogen Ratio Independently Predicts Acute Kidney Injury in Infants With Ventricular Septal Defect Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Abstract Background: Acute kidney injury (AKI) is a common and serious complication faced by children following ventricular septal defect (VSD) surgery with cardiopulmonary bypass (CPB). The objective of this study was..

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Use of bivalirudin for anticoagulation in pediatric extracorporeal membrane oxygenation (ECMO)

Abstract This study describes the use of bivalirudin in children on extracorporeal membrane oxygenation (ECMO). Pediatric patients receiving bivalirudin were compared to patients receiving heparin as the anticoagulant on ECMO...

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Epidemiology of Acute Kidney Injury After Neonatal Cardiac Surgery

Abstract Objectives:  Cardiac surgery–associated acute kidney injury occurs commonly following congenital heart surgery and is associated with adverse outcomes. This study represents the first multicenter study of neonatal cardiac surgery–associated acute..

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Procalcitonin and Early Postoperative Infection After Pediatric Cardiopulmonary Bypass Surgery

Abstract Objectives Systemic inflammation and bacterial infections are critical occurrences after pediatric cardiac surgery. Elevated white blood cell count and C-reactive protein cannot discriminate between these two conditions in the..

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Timely Use of Venous-Arterial ECMO to Treat Congenital Pediatric Junctional Ectopic Tachycardia: A Case Report

Abstract Supraventricular tachycardia is the most common tachyarrhythmia in pediatrics. Although postoperative junctional ectopic tachycardia (JET) is a known complication of congenital heart surgery that is typically transient, congenital JET..

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Native Aortic Root Thrombosis After Norwood Palliation for Hypoplastic Left Heart Syndrome

Abstract Background Norwood palliation for hypoplastic left heart syndrome typically results in retrograde perfusion of the native aortic root. This may predispose to native aortic root thrombosis (NART). Methods Patients..

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The use of thromboelastography (TEG) and rotational thromboelastometry (ROTEM) in neonates: a systematic review

Abstract “Developmental hemostasis” refers to the dynamic process of gradual hemostatic maturation. Conventional coagulation tests seem to fail to accurately depict the in vivo hemostasis, while viscoelastic tests, thromboelastography (TEG),..

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Neonatal Cardiopulmonary Bypass Circuit Blood Prime Quality Analysis

Abstract Blood-primed cardiopulmonary bypass circuits are frequently necessary to achieve safe support during pediatric open-heart surgery. Literature is lacking regarding suitable prime constituents or methods for achieving a physiologically appropriate..

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Severe Pulmonary Hemorrhage in a Neonate With Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation

Abstract Pulmonary hemorrhage (PH) is an infrequent and potentially fatal event in term neonates. Reports of successful management of PH on extracorporeal membrane oxygenation (ECMO) are limited, given the accentuated..

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A contemporary review of paediatric heart transplantation and mechanical circulatory support

Abstract Improvements in the care of children with cardiomyopathy, CHDs, and acquired heart disease have led to an increased number of children surviving with advanced heart failure. In addition, the..

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Subzero balance - simple modified ultrafiltration (SBUF-SMUF) technique for pediatric cardiopulmonary bypass

Abstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..

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Efficacy of CytoSorb in a Pediatric Case of Severe Multisystem Inflammatory Syndrome (MIS-C): A Clinical Case Report

This case reports on a 14-year-old previously healthy girl who was referred to the Pediatric Intensive Care Unit (PICU) with a suspicion of multisystem inflammatory syndrome in children (MIS-C) and..

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Tetralogy of Fallot (TOF)

Tetralogy of Fallot (TOF) is a cardiac anomaly that refers to a combination of four related heart defects that commonly occur together. The four defects are:  − a hole between the right..

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Biventricular Support Using ProtekDuo Cannula in a Child

Abstract We report a successful pediatric bridge to transplant following application of the ProTekDuo Cannula to provide right ventricular support in a 12-year-old child with biventricular cardiomyopathy and on left..

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Anticoagulation and Transfusion Management During Neonatal and Pediatric Extracorporeal Membrane Oxygenation: A Survey of Medical Directors in the United States

Abstract OBJECTIVES:  To compare current practices within the United States of anticoagulation management and blood transfusion in neonatal and pediatric extracorporeal membrane oxygenation patients with a 2013 international report. DESIGN: ..

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Dysbiosis and Intestinal Barrier Dysfunction in Pediatric Congenital Heart Disease Is Exacerbated Following Cardiopulmonary Bypass

Summary There are no data evaluating the microbiome in congenital heart disease following cardiopulmonary bypass. The authors evaluated patients with congenital heart disease undergoing cardiopulmonary bypass and noncardiac patients undergoing..

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Postoperative Cerebral Oxygen Saturation in Children After Congenital Cardiac Surgery and Long-Term Total Intelligence Quotient: A Prospective Observational Study

Abstract OBJECTIVES:  During the early postoperative period, children with congenital heart disease can suffer from inadequate cerebral perfusion, with possible long-term neurocognitive consequences. Cerebral tissue oxygen saturation can be monitored..

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Stress-Induced (Takotsubo) Cardiomyopathy After Liver Transplant Rescued with Venoarterial Extracorporeal Membrane Oxygenation

Abstract Here, we report the case of a 55 year old male patient without significant preexisting cardiovascular disease who received a deceased donor liver transplant. Intraoperatively, the patient developed cardiogenic..

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Neurocognitive disorders amongst patients with congenital heart disease undergoing procedures in childhood

Abstract Background Amongst children with congenital heart disease (CHD), earlier age of repair improves cardiovascular outcomes. The effects of early intervention on neurodevelopment remains unclear. We assessed the association between..

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Understanding and managing the complex balance between bleeding and thrombosis following cardiopulmonary bypass in paediatric cardiac surgical patients

Abstract Bleeding in the perioperative period of congenital heart surgery with cardiopulmonary bypass is associated with increased morbidity and mortality both from the direct effects of haemorrhage as well as..

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Bivalirudin May Reduce the Need for Red Blood Cell Transfusion in Pediatric Cardiac Patients on Extracorporeal Membrane Oxygenation

Abstract We retrospectively compared anticoagulation with heparin and bivalirudin for 32 consecutive children under 18 years old during extracorporeal membrane oxygenation (ECMO) in our pediatric cardiac intensive care unit (PCICU). Between September..

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