A Trip to the Moon: Neonatal ABO Non-Compatible Heart Transplant in Donor Circulatory Death


Donation after Circulatory Death (DCD) is gaining worldwide acceptance as an adjunct to brain death (BD) in transplant surgery. Initially performed for abdominal organs procurement, DCD was then carried out for heart and lung transplants (HT). Most DCD-HT protocols regard their first cases to be performed with both donor and recipient located in the same institution. The first three cases were performed in Denver (Colorado, USA) in 2008 (ultra-fast procurement, without in situ graft evaluation), and since then few records of children have been published. Several ways of harvesting, including ultra-fast, normothermic regional perfusion -NRP- or on peripheral Extra Corporeal Membrane Oxygenation (ECMO) and preservation during transport (cold storage -CS-, Transmedics Organ Care System -OCS-) allow different combinations possible, as displayed by groups in Australia, Belgium, Great Britain, and other countries.


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