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Prone positioning during veno-venous extracorporeal membrane oxygenation: a systematic review and meta-analysis

Abstract Purpose The evidence supporting the benefit on clinical outcomes of prone positioning during veno-venous extracorporeal membrane oxygenation (V-V ECMO) for acute hypoxemic respiratory failure remains inconclusive. We aimed to..

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Assembling, Priming, and Storing Circuits for Pediatric and Neonatal Extracorporeal Membrane Oxygenation

Abstract The storing of dry-assembled and primed extracorporeal membrane oxygenation (ECMO) circuits is common practice and endorsed by the Extracorporeal Life Support Organization (ELSO) for up to 30 days. We..

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Predictors of Mortality in Venoarterial Extracorporeal Membrane Oxygenation Regardless of Early Left Ventricular Unloading: A National Experience

Abstract Objective The use of an intra-aortic balloon pump (IABP) has been suggested to unload the left ventricle while on venoarterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock (CS), leading..

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Extracorporeal Membrane Oxygenation in the Awake or Extubated Patient

Abstract Extracorporeal membrane oxygenation (ECMO) traditionally has been used under deep sedation and mechanical ventilation. However, recent advancements have led to the development of awake ECMO strategies, allowing patients to..

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Prognostic Significance of Driving Pressure for Initiation and Maintenance of ECMO in Patients with Severe ARDS: A Systematic Review and…

Abstract Introduction: In life-threatening conditions like severe acute respiratory distress syndrome (ARDS), rescue interventions like extracorporeal membrane oxygenation (ECMO) should be initiated urgently to resolve an otherwise potentially adverse clinical outcome...

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Ductus Arteriosus Patency for the Hemodynamic Management of Newborns With Pulmonary Hypertension on Veno-Venous Extracorporeal Membrane Oxygenation

Abstract In neonates with pulmonary hypertension (PH) supported on veno-venous extracorporeal membrane oxygenation (VV-ECMO), keeping the ductus arteriosus (DA) open ensures a high cardiac output of well-oxygenated blood through the..

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The ProtekDuo Cannula for Venopulmonary ECMO as Bridge to Lung Transplantation: A Single Center Case Series

Abstract Venovenous extracorporeal membrane oxygenation is the most commonly used mode of support in pre-lung transplant recipients. In patients who experience right ventricular dysfunction, venopulmonary ECMO is an excellent option..

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Pulse Oximetry and Arterial Blood Gas Oxygen Saturation Discrepancies and Mortality in Extracorporeal Cardiopulmonary Resuscitation Patients: An Extracorporeal Life Support…

Abstract Objectives:  Previous studies have shown that inaccurate peripheral oxygen saturation (SpO2) readings compared with arterial oxygen saturation (SaO2) may occur in extracorporeal membrane oxygenation (ECMO) patients. We hypothesized that..

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Trends in cardiac arrest care and mortality in United States emergency departments over eight years

Abstract Introduction Cardiac arrest in the emergency department (ED) is a rare event. Prior studies have used dedicated cardiac arrest registries, but few have leveraged “big data” from electronic healthcare..

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Development of a New Longitudinal Ordinal Outcome for Clinical Trials in ECMO Patients

Abstract Rationale: Randomised clinical trials in intensive care often prioritize disease-focused outcomes rather than patient-centred outcomes. Objective: To report and evaluate the ‘Daily Organ Support for patients on extracorporeal membrane..

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Predictors of successful weaning from veno-arterial extracorporeal membrane oxygenation (V-A ECMO): A systematic review and meta-analysis

Abstract Background Venoarterial extracorporeal membrane oxygenation (V-A ECMO) use to support patients in cardiac failure is increasing. Despite this increased use, predicting successful weaning from ECMO can be challenging, no..

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Investigation of Inflammatory Reduction During Extracorporeal Membrane Oxygenation Using a Novel Cytokine Adsorption Column: A Rat Model Study

Abstract Background: Cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO) are widely used. Previous methods to reduce inflammation have shown inconsistent results. We developed a cytokine adsorption column using polymethyl methacrylate..

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Worldwide application and valuation of extracorporeal membrane oxygenation support during the COVID-19 pandemic (WAVES)

Abstract Objective The outcomes of COVID-19 patients on venovenous extracorporeal membrane oxygenation (VV-ECMO) varied. We aim to investigate the variability concerning location and timeframe. We conducted a retrospective analysis of..

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Experiences With International Transports on Extracorporeal Membrane Oxygenation: Special Considerations and Challenges

Abstract Extracorporeal membrane oxygenation (ECMO) is a crucial support for patients with severe cardiac or respiratory failure, but its availability is limited, often requiring patient transport to specialized centers. Only..

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Impact of ICU-Based Extracorporeal Membrane Oxygenation and Blood Purification Therapy on the Time Required for Early Rehabilitation

Abstract Background Early rehabilitation in an intensive care unit (ICU) can shorten the ICU stay and reduce the associated risks and costs. However, mobilization has been shown to be slower..

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High-Granularity Machine Learning Prediction of Acute Brain Injury in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation

Abstract Acute brain injury (ABI) is prevalent among patients undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO) and significantly impact recovery. Early prediction of ABI could enable timely interventions to prevent adverse..

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Device profile of the integrated VitalFlow ECMO system

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a life support system composed of a pump, an oxygenator, hemocompatible component coating, and integrated monitoring. ECMO systems have evolved greatly since the..

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Veno-venous extracorporeal membrane oxygenation exacerbates lung ischaemia–reperfusion injury in a rat model

Abstract OBJECTIVES Although lung transplantation has experienced great development in the past decades, the survival rate remains low, and lung ischaemia–reperfusion injury during transplantation is a major cause of primary..

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Mechanical circulatory support in cardiogenic shock: translating trial evidence into real-world practice

Abstract While iterative developments have improved outcomes of patients with myocardial infarction, mortality in patients with acute myocardial infarction cardiogenic shock (AMI-CS) remains stubbornly high. Several promising treatments have ultimately..

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Patient Characteristics and Extracorporeal Membrane Oxygenation Outcomes at Nelson Mandela Children’s Hospital: A South African Experience

Abstract This study aimed to describe patient characteristics, mortality, and morbidity outcomes in children at a South African extracorporeal membrane oxygenation (ECMO) center. Fifty-seven patients required ECMO from 2018 to..

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Protocol for the development of NHMRC-endorsed guidelines for extracorporeal membrane oxygenation using GRADE methodology

Abstract Introduction The last 15 years have seen a rapid expansion in the use of extracorporeal life support. ECMO has evolved from a rescue treatment available in a few expert..

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Troubleshooting for the Empowered ECMO Nurse

Abstract An Introduction to ECMO Troubleshooting Like other ECMO nurses, I will never forget the first time I had to troubleshoot an  circuit. My patient had returned to the intensive care..

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Utilization and outcomes of nonintubated extracorporeal membrane oxygenation as a bridge to lung transplant

Abstract Background Nonintubated extracorporeal membrane oxygenation (ECMO) has been increasingly utilized for patients with severe respiratory failure. Since data on its use as a bridge to lung transplant remain limited,..

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High-risk pulmonary embolism: the significance and perspectives of pulmonary reperfusion

Abstract Rapid hemodynamic stabilization and restoration of pulmonary perfusion are the cornerstones of treatment for high-risk pulmonary embolism (PE). While all current guidelines recommend systemic thrombolysis (SYS) as the first-line..

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Extracorporeal Membrane Oxygenation as a Bridge to Recovery in Children With Severe Necrotizing Pneumonia: Case Report

Abstract Necrotizing pneumonia is a severe complication of bacterial or viral pneumonia that can lead to refractory respiratory failure in children. Extracorporeal membrane oxygenation (ECMO) has emerged as a vital..

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Outcomes after hospital discharge in children requiring post-cardiotomy extracorporeal membrane oxygenation: A binational retrospective cohort study

Abstract Objectives To describe longer-term survival and morbidity outcomes after hospital discharge in a binational cohort of children who required extracorporeal membrane oxygenation after cardiac surgery. Methods This was a..

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Bloodless lung transplantation: Comparison between 2 central venoarterial extracorporeal membrane oxygenation anticoagulation strategies and their impact on lung transplant outcomes

Abstract Objective To report differences between 2 anticoagulation protocols during venoarterial extracorporeal membrane oxygenation (VA-ECMO) intraoperative support and their effects on outcomes after lung transplantation. Methods We performed a retrospective..

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Exploring the role of inflammation and proinflammatory proteins in coagulopathy during venovenous extracorporeal membrane oxygenation

Abstract Background Coagulopathy frequently complicates venovenous extracorporeal membrane oxygenation (VV ECMO) procedures, yet its underlying mechanism remains elusive. This retrospective study aimed to identify factors contributing to coagulopathy during VV..

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Analysis of the feasibility of a low-anticoagulation strategy in patients undergoing post-cardiotomy extracorporeal membrane oxygenation: a retrospective cohort study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is increasingly used in patients after cardiac surgery; however, anticoagulation management has consistently been challenging. This study aimed to explore the feasibility of a..

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Mechanical Circulatory Support for Acute Myocardial Infarction Cardiogenic Shock: Review and Recent Updates

Abstract Cardiogenic shock (CS) in acute myocardial infarction (AMI) is a life-threatening syndrome characterized by systemic hypoperfusion that can quickly progress to multiorgan failure and death. Various devices and configurations..

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