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The Interplay of Inflammation and Coagulation in COVID-19 Patients Receiving Extracorporeal Membrane Oxygenation Support

Abstract Objective Bleeding and thrombosis are common complications during Extracorporeal Membrane Oxygenation (ECMO) support for COVID-19 patients. We sought to examine the relationship between inflammatory status, coagulation effects, and observed..

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Kounis syndrome caused by protamine shock after coronary intervention: A case report

Abstract We report a case of Kounis syndrome that led to shock after protamine administration during percutaneous coronary intervention (PCI). A man in his 50s was admitted to the nearest..

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Neurological Complications in COVID-19 Patients With ECMO Support: A Systematic Review and Meta-Analysis

Abstract Background Patients with  (COVID-19)-related  (ARDS) increasingly receive  (ECMO) support. While ECMO has been shown to increase risk of stroke, few studies have examined this association in COVID-19 patients. Objective We conducted a..

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The Effectiveness of Three Different Curricular Models to Teach Fundamental ECMO Specialist Skills to Entry Level Perfusionists

Abstract The dramatic increase in the use of extracorporeal membrane oxygenation (ECMO) over the last decade with the concomitant need for ECMO competent perfusionists has raised questions of how well..

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Extracorporeal Membrane Oxygenation Transport in the Wake of the Pandemic Is Feasible and Safe

Abstract There are quarter of a million articles in PubMed since the wake of the COVID-19 pandemic with about fifteen hundred articles on extracorporeal membrane oxygenation (ECMO) alone. Those that are entrenched..

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Hemodynamics of small arterial return cannulae for venoarterial extracorporeal membrane oxygenation

Abstract Background Venoarterial extracorporeal membrane oxygenation (ECMO) provides mechanical support for critically ill patients with cardiogenic shock. Typically, the size of the arterial return cannula is chosen to maximize flow...

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Impella to Unload the Left Ventricle During Peripheral Extracorporeal Membrane Oxygenation

Abstract Peripheral venoarterial extracorporeal membrane oxygenation (VA ECMO) for acute cardiac failure reestablishes normal oxygen delivery and perfusion. However, VA ECMO can be limited by insufficient ventricular unloading, resulting in..

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Prone position during venovenous extracorporeal membrane oxygenation: survival analysis needed for a time-dependent intervention

Abstract We read with great interest the paper of Giani and colleagues titled "Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data..

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Right Ventricular Dysfunction is Associated with Increased Mortality in Patients Requiring Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019

Abstract Respiratory failure caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is associated with mortality. Patients unresponsive to conventional therapy may benefit from temporary venovenous extracorporeal membrane oxygenation (VV-ECMO). We..

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Awake ECMO for COVID-19 Induced Acute Respiratory Distress Syndrome

Abstract The outcome of COVID-19 patients treated on intensive care units (ICU) is unsatisfying (1). Veno-venous extracorporeal membrane oxygenation (vv-ECMO) can serve as a rescue strategy when patients deteriorate during..

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Bleeding and thrombotic events in adults supported with venovenous extracorporeal membrane oxygenation: an ELSO registry analysis

Abstract Purpose: This study aimed at analyzing the prevalence, mortality association, and risk factors for bleeding and thrombosis events (BTEs) among adults supported with venovenous extracorporeal membrane oxygenation (VV-ECMO). Methods:..

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Outcomes of Extubated COVID and Non-COVID Patients Receiving Awake Venovenous Extracorporeal Membrane Oxygenation

Abstract Cessation of continuous analgesia and sedation in patients with acute respiratory distress syndrome (ARDS) receiving venovenous (VV) extracorporeal membrane oxygenation (ECMO) facilitates early extubation, family, patient and provider engagement, and mobility...

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Atrial Arrhythmias During Venovenous ECMO: A Cry for Help?

Abstract WE READ with great interest the work by Li et al. in the Journal of Cardiothoracic and Vascular Anesthesia. In their work, the authors characterized the incidence and effect on outcomes..

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Effect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation

Abstract Importance  The optimal approach to the use of venoarterial extracorporeal membrane oxygenation (ECMO) during cardiogenic shock is uncertain. Objective  To determine whether early use of moderate hypothermia (33-34 °C) compared with..

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Mobile Extracorporeal Membrane Oxygenation for Covid-19 Does Not Pose Extra Risk to Transport Team

Abstract Previous experience has shown that transporting patients on extracorporeal membrane oxygenation (ECMO) is a safe and effective mode of transferring critically ill patients requiring maximum mechanical ventilator support to..

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Extracorporeal Membrane Oxygenation for Septic Shock in Children

Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue treatment used in children and adults with reversible cardiorespiratory failure. The role of ECMO is not fully established in pediatric sepsis. In..

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Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation

Abstract Objectives:  Children receiving prolonged extracorporeal membrane oxygenation (ECMO) support may benefit from tracheostomy during ECMO by facilitating rehabilitation; however, the procedure carries risks, especially hemorrhagic complications. Knowledge of tracheostomy practices and outcomes of..

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Ambulatory home wearable lung: progress and future directions

Abstract Extracorporeal life support (ECLS) was first implemented as an extension of cardiopulmonary bypass technology. The early use of ECLS in patients with acute respiratory distress syndrome (ARDS) was discouraging,..

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Intraoperative support during lung transplantation

Abstract The role of intraoperative mechanical support during lung transplantation (LTx) is essential to provide a safe hemodynamic and ventilatory status during critical intraoperative events. This hemodynamic and ventilatory stability..

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Blood Pumps for Extracorporeal Membrane Oxygenation: Platelet Activation During Different Operating Conditions

Abstract Extracorporeal membrane oxygenation (ECMO) is a therapy used in severe cardiopulmonary failure. Blood is pumped through an artificial circuit exposing it to nonphysiologic conditions, which promote platelet activation and..

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The Disconnect Between Extracorporeal Circulation and the Microcirculation

Abstract Extracorporeal circulation (ECC) procedures, such as cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), take over the function of one or more organs, providing clinicians time to treat underlying..

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The physiology of extracorporeal membrane oxygenation: The Fick principle

Abstract Extracorporeal membrane oxygenation (ECMO) can be delivered in veno-arterial (VA) and veno-venous (VV) configurations based on the cannulation strategy. VA and VV ECMO are delivered primarily for haemodynamic and..

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A mock circulation loop to evaluate differential hypoxemia during peripheral venoarterial extracorporeal membrane oxygenation

Abstract Introduction Peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) creates a retrograde flow along the aorta competing with the left ventricle (LV) in the so-called ‘mixing zone’ (MZ). Detecting it..

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Tracheal stenting on venovenous ECMO with a dual lumen right atrium-to-pulmonary artery cannula in a COVID-19 patient with an inferior…

Abstract A 47-year-old man, with no medical history, was diagnosed with severe COVID-19 ARDS and pulmonary embolism. Venovenous extracorporeal membrane oxygenation (ECMO) was required for impossibility to deliver protective ventilation...

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Fracture of dual lumen cannula leading to cerebrovascular accident in a patient supported with ECMO

Abstract Extended duration extracorporeal membrane oxygenation (ECMO), using dual-lumen cannulas, is being used with increased frequency to support patients, including those with COVID-19; both as a bridge to transplant and..

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Extracorporeal Life Support for Status Asthmaticus

Abstract Extracorporeal life support (ECLS) may be life saving for patients with status asthmaticus (SA), a difficult-to-treat, severe subset of asthma. Contemporary ECLS outcomes for SA in teens and young..

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Use of a Reperfusion Cannula for Acute Limb Ischemia in a Patient with Carotid Artery Extracorporeal Membrane Oxygenation Cannulation

Abstract Acute limb ischemia is a rare but potentially devastating event in a critically ill patient. In the pediatric population, limb ischemia is usually related to iatrogenic vascular damage and..

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Somatic Support with Veno-venous ECMO in a Pregnant Woman with Brain Death: A Case Report

Abstract Supporting homeostasis in a pregnant woman with brain death to achieve fetal viability is called somatic support. We present a case of young pregnant woman at 21 weeks’ gestation..

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Survival on Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock: Which Lactate Is Most Useful?

Abstract Prognostic significance of elevated serum lactate in patients on venoarterial extracorporeal membrane oxygenation (ECMO) is widely known. Our objective was to study the utility of lactate measured at different points of..

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Agreement Between the TEG 6s and TEG 5000 Analyzers in Extracorporeal Membrane Oxygenation

Abstract Thromboelastography (TEG) evaluates viscoelastic properties of blood clot formation. The TEG 5000 analyzer is commonly used but prone to errors related to vibration or operator error. The TEG 6s..

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