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To Balloon or Not to Balloon? The Effects of an Intra-Aortic Balloon-Pump on Coronary Artery Flow during Extracorporeal Circulation Simulating…

Abstract ECMO is the most frequently used mechanical support for patients suffering from low cardiac output syndrome. Combining IABP with ECMO is believed to increase coronary artery blood flow, decrease..

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ECMO implantation training: Needle penetration in 3D printable materials and porcine aorta

Abstract Aim Patients with cardiogenic shock or ARDS, for example, in COVID-19/SARS-CoV-2, may require extracorporeal membrane oxygenation (ECMO). An ECLS/ECMO model simulating challenging vascular anatomy is desirable for cannula insertion..

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Pediatric Extracorporeal Life Support Transport in Western Canada

Abstract This retrospective cohort study describes all children transported on extracorporeal life support (ECLS) by the Stollery Children’s Hospital Pediatric Transport team (SCH-PTT) between 2004 and 2018. We compared outcomes..

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Extracorporeal membrane oxygenation in the forensic setting: A series of 19 forensic cases

Abstract Extracorporeal membrane oxygenation (ECMO) employs vascular cannulation and a gas exchange circuit to provide support to patients with severely compromised cardiopulmonary function. ECMO is often the last intervention taken..

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Noninvasive optical measurement of microvascular cerebral hemodynamics and autoregulation in the neonatal ECMO patient

Abstract Background Extra-corporeal membrane oxygenation (ECMO) is a life-saving intervention for severe respiratory and cardiac diseases. However, 50% of survivors have abnormal neurologic exams. Current ECMO management is guided by..

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Le prime linee guida per l'uso dell'ECMO nei pazienti pediatrici sottoposti a trapianto di cellule staminali ematopoietiche

Abstract È l’Ospedale Pediatrico Bambino Gesù, in collaborazione con 5 società scientifiche internazionali, a mettere per la prima volta a disposizione di rianimatori e oncoematologi le Linee Guida per il trattamento con ossigenazione extracorporea..

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Use of Extracorporeal Membrane Oxygenation as Bridge to Replacement Therapies in Cardiogenic Shock: Insights From the Extracorporeal Life Support Organization

Abstract Background: There has been increasing use of extracorporeal membrane oxygenation (ECMO) as bridge to heart transplant (orthotopic heart transplant [OHT]) or left ventricular assist device (LVAD) over the last..

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Extracorporeal membrane oxygenation in children receiving haematopoietic cell transplantation and immune effector cell therapy: an international and multidisciplinary consensus statement

Abstract Use of extracorporeal membrane oxygenation (ECMO) in children receiving haematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable advancements..

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Adrenaline improves regional cerebral blood flow, cerebral oxygenation and cerebral metabolism during CPR in a porcine cardiac arrest model using…

Abstract Background The effects of adrenaline on cerebral blood vessels during cardiopulmonary resuscitation (CPR) are not well understood. We developed an extracorporeal CPR model that maintains constant low systemic blood..

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Limb Amputation Following Extracorporeal Membrane Oxygenation Therapy Among Survivors: A Nationwide Cohort Study from South Korea

Abstract We aimed to investigate the incidence of limb amputation due to vascular complications related to extracorporeal membrane oxygenation (ECMO) therapy among survivors and examine its association with long-term mortality in these..

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The Use of Cerebral NIRS Monitoring to Identify Acute Brain Injury in Patients With VA-ECMO

Abstract Acute brain injury (ABI) increases morbidity and mortality in patients with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Optimal neurologic monitoring methods have not been well-explicated. We studied the use of..

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Pediatric ECMO: unfavorable outcomes are associated with inflammation and endothelial activation

Abstract Background Inflammatory and endothelial activation responses during extracorporeal membrane oxygenation (ECMO) support in children are poorly understood. In this study, we aimed to determine if circulating inflammatory, endothelial activation,..

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Thrombosis in Extracorporeal Membrane Oxygenation (ECMO) Circuits

Abstract Thrombosis in extracorporeal membrane oxygenation (ECMO) circuits remains a frequent complication. We characterize the location, extent, structure, and clinical implications of thrombi in 53 ECMO circuits from 46 pediatric patients...

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Left ventricular assist device implants in patients on extracorporeal membrane oxygenation: do we need cardiopulmonary bypass?

Abstract     OBJECTIVES Implanting a durable left ventricular assist device (LVAD) in a patient on extracorporeal life support (ECLS) is challenging. The goal of this study was to compare..

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Impact of Arterial Carbon Dioxide and Oxygen Content on Cerebral Autoregulation Monitoring Among Children Supported by ECMO

Abstract Background Cerebral autoregulation (CA) impairment is associated with neurological complications among children supported by extracorporeal membrane oxygenation (ECMO). Severe variations of arterial CO2 (PaCO2) and O2 (PaO2) tension after ECMO onset..

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Central, peripheral ECMO or CPB? Comparison between circulatory support methods used during lung transplantation

Abstract Background Chronic obstructive pulmonary disease, cystic fibrosis and usual interstitial pneumonia are three most common indications for lung transplantation (LuTx) in Poland. As a result of irreversible destruction of..

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Use of extracorporeal membrane oxygenation for heart graft dysfunction in adults: incidence, risk factors and outcomes in a multicentric study

Abstract Background: The decision about whether to use venoarterial extracorporeal membrane oxygenation (VA-ECMO) in patients with cardiac graft dysfunction (GD) is usually made on a case-by-case basis and is guided by..

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Lactate levels as a prognostic predict in cardiogenic shock under venoarterial extracorporeal membrane oxygenation support

Abstract Introduction and objectives Lactate and its evolution are associated with the prognosis of patients in shock, although there is little evidence in those assisted with an extracorporeal venoarterial oxygenation..

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Short-term mechanical circulatory support in elderly patients

Abstract Background Age over 70 years seems to confer poor prognosis for patients under mechanical circulatory support (MCS). Advanced age is usually a relative contraindication. Our objective was to assess the..

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Stroke patterns and cannulation strategy during veno‑arterial extracorporeal membrane support

Abstract Stroke has potentially devastating consequences for patients receiving veno-arterial extracorporeal membrane support (VA-ECMO). Arterial cannulation sites for VA-ECMO include the ascending aorta, axillary artery, and femoral artery. However, the..

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What Determines the Arterial Partial Pressure of Carbon Dioxide on Venovenous Extracorporeal Membrane Oxygenation?

Abstract Rapid reductions in PaCO2 during extracorporeal membrane oxygenation (ECMO) are associated with poor neurologic outcomes. Understanding what factors determine PaCO2 may allow a gradual reduction, potentially improving neurologic outcome. A simple..

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Extracorporeal Cardiopulmonary Resuscitation and Survival After Refractory Cardiac Arrest: Is ECPR Beneficial?

Abstract The level of evidence of expert recommendations for starting extracorporeal cardiopulmonary resuscitation (ECPR) in refractory out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) is low. Therefore, we reported..

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Use of Hemoadsorption in Patients With Severe Intoxication Requiring Extracorporeal Cardiopulmonary Support—A Case Series

Abstract Drugs intoxications often lead to severe vasoplegia and cardiogenic shock, and VA-ECMO represents a viable therapy option. However, as cardiopulmonary support is not contributing to the removal of the..

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Automated and cost-efficient early detection of hemolysis in patients with extracorporeal life support: Use of the hemolysis-index of routine clinical…

Abstract Purpose Patients with  (ECLS) are at risk for hemolysis-related complications. Therefore, monitoring of free hemoglobin (fHb) levels is indicated. Conventional methods for fHb are laborious and not always available. Here..

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No extra COVID-19 risk for ECMO transport teams, reports ASAIO Journal

Abstract Newswise — November 22, 2021 –  – with no increased risk of transmitting COVID-19 transmission to ECMO transport team members following standard precautions, reports a study in the , official journal of..

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Early mobilisation algorithm for the critical patient. Expert recommendations

Abstract Introduction  (ICU)-acquired weakness is developed by 40%–46% of patients admitted to ICU. Different studies have shown that Early Mobilisation (EM) is safe, feasible, cost-effective and improves patient outcomes in..

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Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Single-Blind,…

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the rescue treatment proposed to patients with refractory cardiogenic shock. The VA-ECMO implantation promotes inflammation and ischemia-reperfusion injuries through the VA-ECMO flow, causing..

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Flow Monitoring of ECMO circuit for detecting Oxygenator Obstructions

Abstract Oxygenator thrombosis during extracorporeal membrane oxygenation (ECMO), is a complication that necessitates component replacement. ECMO centers monitor clot burden by intermittent measurement of pressure drop across the oxygenator. An..

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Postcardiotomy Extracorporeal Membrane Oxygenation: Narrative Review Navigating the Ethical Issues

Abstract Postcardiotomy shock (PCS) is an uncommon and life-threatening .  (ECMO) is the first line of mechanical  for treating PCS when medical therapies are insufficient. Reaching a “therapeutic ceiling” or a “bridge to..

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Effect of body mass index on the clinical outcomes of adult patients treated with venoarterial ECMO for cardiogenic shock

Abstract Objective Current guidelines consider obesity to be a relative contraindication to veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock. The authors investigated the effect of body mass index..

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