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The Surface of a PMP Hollow Fiber Membrane Was Modified with a Diamond-like Carbon Film to Enhance the Blood Compatibility…

Abstract The contact between the blood and the surface of medical materials causes a series of rejection reactions. In this process, the plasma protein is adsorbed to the surface of..

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Circuit change in neonatal and pediatric extracorporeal membrane oxygenation is associated with adverse outcomes

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) circuits may be changed during the run for multiple reasons; however, these circuit changes may be associated with adverse events. Predictors for undergoing a..

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Central Extracorporeal Membrane Oxygenation Support Following Calcium Channel Blocker Overdose in Children

Abstract Refractory vasodilatory shock (RVS) following massive calcium channel blocker (CCB) overdose remains a challenging clinical entity. Peripheral venoarterial extracorporeal membrane oxygenation (ECMO) has proven useful in several cases of..

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Biofilm Assessment and Metagenomic Analysis of Venoarterial Extracorporeal Membrane Oxygenation Cannulas and Membrane Oxygenators

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) exposes the patient to infectious complications related to the cannulas or the site of insertion. The aim of the current study was to investigate..

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Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomised controlled trials and propensity score matched studies.

Abstract Background: Cardiogenic shock is associated with high mortality. In refractory shock, it is unclear if mechanical circulatory support (MCS) devices improve survival. We conducted a systematic review and network meta-analysis..

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Epidemiology of ischemic stroke and hemorrhagic stroke in venoarterial extracorporeal membrane oxygenation

Abstract Background While venoarterial extracorporeal membrane oxygenation (V‑A ECMO) provides lifesaving supportfor cardiopulmonary failure, complications may increase mortality, with few studies focusing on ischemic/hemor‑rhagic stroke. We aimed to determine the..

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ECMO as an Indirect Bridge to Durable Left Ventricular Assist Device Implantation

Abstract Introduction: The need for preoperative extracorporeal membrane oxygenation (ECMO) support prior to left ventricular assist device(LVAD) therapy has been associated with increased mortality. Our study investigated the impact of de-escalating..

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Extracorporeal Membrane Oxygenation Without Invasive Ventilation for Respiratory Failure in Adults: A Systematic Review

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation (ECMO) is an advanced treatment for acute severe respiratory failure. Patients on ECMO are frequently maintained sedated and immobilized until weaning from ECMO, first, and..

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Outcomes of Recipients Aged 65 Years and Older Bridged to Lung Transplant With Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant (BTT) has been used for critically ill candidates with excellent outcomes, but data on this strategy in older recipients..

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A Novel Approach to Measuring Physiologic Changes during Ambulation for a Patient with Post Infarct VSD Supported on Femoral IABP…

Abstract Post-infarct ventricular septal defect (PIVSD) is a rare, life-threatening complication following acute myocardial infarction (MI), associated with high overall mortality. Interventions include medical management, percutaneous closure, and/or surgical closure...

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Obesity is Associated with Increased Mortality in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background: Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) is used to support patients with cardiac and respiratory failure. The relationship between obesity and VA-ECMO outcomes is unknown. Objectives: To determine the relationship between..

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Tranexamic Acid for Bleeding Management in Adult Patients on Extracorporeal Membrane Oxygenation

Abstract This study described the outcomes of patients receiving topical, nebulized, endobronchial, or systemic tranexamic acid (TXA) for bleeding events while on extracorporeal membrane oxygenation (ECMO). We performed a single-center..

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Platelets and fibrinogen matter when bleeding on ECMO

Abstract We have read with interest the work by Helms et al., a single-center study with 30 patients (16 on veno-venous and 14 on veno-arterial extracorporeal membrane oxy-genation (ECMO)), with..

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Impella – Current issues and future expectations for the percutaneous, microaxial flow left ventricular assist device

Abstract Summary The importance of temporary mechanical circulatory support for treating acute heart failure with cardiogenic shock is increasingly recognized, and Impella (Abiomed, Danvers, MA, USA) has received particular attention..

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Anticoagulation and Bleeding during Veno-Venous Extracorporeal Membrane Oxygenation: Insights from the PROTECMO Study

Abstract Rationale: Definitive guidelines for anticoagulation management during veno-venous extracorporeal membrane oxygenation (VV ECMO) are lacking, while bleeding complications continue to pose major challenges. Objectives: To describe anticoagulation modalities and..

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Preload Responsiveness in Patients With Acute Respiratory Distress Syndrome Managed With Extracorporeal Membrane Oxygenation

Abstract A restrictive fluid strategy is recommended in patients with acute respiratory distress syndrome (ARDS) managed with venovenous extracorporeal membrane oxygenation (VV ECMO). However, there are no established predictors for..

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Anti-Factor-Xa and Activated Partial Thromboplastin Time Concordance and Outcomes in Adults Undergoing Extracorporeal Membrane Oxygenation: A Secondary Analysis of the…

Abstract OBJECTIVES:  To determine the concordance between activated partial thromboplastin time (aPTT) and anti-factor-Xa (anti-Xa) in adults undergoing extracorporeal membrane oxygenation (ECMO) and to identify the factors associated with discordant..

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A Mortality Prediction Score for Patients With Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO): The PREDICT VV-ECMO Score

Abstract Mortality prediction for patients with the severe acute respiratory distress syndrome (ARDS) supported with veno-venous extracorporeal membrane oxygenation (VV-ECMO) is challenging. Clinical variables at baseline and on day 3..

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Left Atrial-Veno Arterial Extracorporeal Membrane Oxygenation as a Bridge to Surgery for Endocarditis–Related Acute Severe Aortic Regurgitation

Abstract Mechanical circulatory support for cardiogenic shock complicated by acute severe aortic regurgitation poses a unique challenge for traditional veno arterial extracorporeal membrane oxygenation (ECMO) because of rapidly rising left..

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Pediatric Highlights From the Extracorporeal Life Support Organization Registry: 2017–2022

Abstract The Extracorporeal Life Support Organization (ELSO) registry which collects data from hundreds of participating centers supports research in ECMO to help improve patient outcomes. The ELSO Scientific Oversight Committee,..

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An International Survey of Extracorporeal Membrane Oxygenation Education and Credentialing Practices

Abstract Background: The use of extracorporeal membrane oxygenation (ECMO) has grown rapidly over the past decades because of evolving indications, advances in circuit technology, and encouraging results from modern trials. Because..

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Utilization of Impella as a Weaning Platform from ECMO is Associated with Increased Survival in Cardiogenic Shock Patients

Abstract Background: Although extracorporeal membrane oxygenation (ECMO) is an integral part of a robust cardiogenic shock program, it is associated with high mortality. The optimal strategy for weaning from ECMO is..

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Acquired blood stream infections during extracorporeal membrane oxygenation in adults: risk factors and outcomes.

Abstract Infection is one of the most frequent complications in the management of ECMO patients. Although there are several studies demonstrating the role of ECMO in patients with pre-existing sepsis,..

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Takotsubo Syndrome and Severe Cardiogenic Shock secondary to Plastic Surgery treated with VA-ECMO. Case Series

Abstract Beside the tremendous developments in cardiac surgical procedures, the use of cardiopulmonary bypass (CPB) remains the gold standard to perform cardiac surgery but is associated with detrimental effects (e.g...

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Algorithmic Approach to Early Extubation in V-V ECMO Patients

Abstract Background: Extubation while receiving V-V ECMO is being considered earlier for patients with respiratory failure. This can facilitate early mobilization, participation in physical therapy, and reduce the potential consequences of..

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Venting the Left Ventricle from the Atrium: A Case Series of transeptal LA Vent VA-ECMO

Abstract Introduction: In cardiogenic shock, peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide hemodynamic support, however this results in adverse left ventricular afterload. Left ventricle (LV) venting (unloading) has favorable effects..

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Mortality on extracorporeal membrane oxygenation: Evaluation of independent risk factors and causes of death during venoarterial and venovenous support

Abstract Introduction Most patients on extracorporeal membrane oxygenation (ECMO) decease during therapy on the system. However, the actual causes of death have not been studied sufficiently. This study analyses the..

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De senectute and the art of medicine: how old is too old for ECMO in cardiogenic shock?

Abstract Complexity and a certain level of uncertainty are inherent to the clinical scenarios faced by the treating teams, often inundated with exhaustive details. Disease arises from a multitude of..

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Peripheral Veno-Arterial-Extracorporeal Membrane Oxygenation for Refractory Septic Shock in Children: A Multicenter Review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is utilized as a rescue therapy in the management of pediatric patients with refractory septic shock. Multiple studies support the use of a central..

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Early Changes in Arterial Partial Pressure of Carbon Dioxide and Blood Pressure After Starting Extracorporeal Membrane Oxygenation in Children: Extracorporeal…

Abstract Objective:  Neurologic complications in pediatric patients supported by extracorporeal membrane oxygenation (ECMO) are common and lead to morbidity and mortality; however, few modifiable factors are known. Design:  Retrospective study..

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