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Cardiopulmonary bypass and VA‑ECMO induced immune dysfunction: common features and differences, a narrative review

Abstract Cardiopulmonary bypass (CPB) and veno-arterial extracorporeal membrane oxygenation are critical tools in contemporary cardiac surgery and intensive care, respectively. While these techniques share similar components, their application contexts differ,..

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Aortic Dissection in a Neonate Receiving Extracorporeal Life Support Therapy: A Case Report

Abstract Extracorporeal life support (ECLS) therapy is increasingly being used to support children with refractory cardiorespiratory failure, but its use is occasionally associated with complications. Neonatal aortic dissection in association..

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Comparison of microbial growth on primed extracorporeal membrane oxygenation circuits in varying environments using different priming solutions

Abstract Background Extracorporeal Membrane Oxygenation (ECMO) is a life support device for patients with severe heart and/or lung failure. Emergency situations require immediate ECMO response. Primed circuits have become a..

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ECMO: more than just a bridge over troubled waters?

Abstract Extracorporeal membrane oxygenation (ECMO) is used in severe cardiorespiratory failure refractory to conventional management, often as a bridge to recovery, long-term support, or transplant. However, some patients might not..

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Continuing ECMO with no possible transition to recovery or transplant

Abstract Controversy has emerged around how to treat patients who were placed on extracorporeal membrane oxygenation (ECMO) expecting recovery, organ transplant, or durable device, but who can no longer be..

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Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A…

Abstract Purpose To assess the association between fluctuations of arterial carbon dioxide early after start of  (ECMO) with  (ICH) or  (IS). Materials and methods This single-center retrospective study included patients who required ECMO..

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Temporal changes in markers of coagulation and fibrinolysis in adults during extracorporeal membrane oxygenation

Abstract Introduction Bleeding and thrombotic events (BTE) are frequent during extracorporeal membrane oxygenation (ECMO). They occur at varying timepoints and may be affected by temporal changes in coagulation and fibrinolysis...

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Evaluation of staged autologous blood transfusion during extracorporeal membrane oxygenation decannulation: A retrospective study

Abstract Background Clinical blood resources are scarce and autologous blood transfusion for extracorporeal membrane oxygenation (ECMO) withdrawal is less studied. Objectives To assess the use of staged  during  decannulation. Methods The study..

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Continuous-Flow Left Ventricular Assist Devices and Valvular Heart Disease: A Comprehensive Review

Abstract Mechanical circulatory support with implantable durable continuous-flow left ventricular assist devices (CF-LVADs) represents an established surgical treatment option for patients with advanced heart failure refractory to guideline-directed medical therapy...

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International treatment outcomes of neonates on extracorporeal membrane oxygenation (ECMO) with persistent pulmonary hypertension of the newborn (PPHN): a systematic…

Abstract Background PPHN is a common cause of neonatal respiratory failure and is still a serious condition and associated with high mortality. Objectives To compare the demographic variables, clinical characteristics,..

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New strategy for distal limb perfusion in veno-arterial extracorporeal membrane oxygenation treatment: application of continuous renal replacement therapy tubing

Abstract Extracorporeal membrane oxygenation (ECMO) is a technology that can temporarily take over the functions of the heart and lungs. Acute kidney injury is a common issue in patients receiving..

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Extracorporeal membrane oxygenation versus cardiopulmonary bypass during transcatheter aortic valve implantation: a meta-analysis of survival benefits

Abstract Since its approval by the Food and Drug Administration in 2011, transcatheter aortic valve implantation (TAVI) has rapidly evolved to become the preferred ultimate intervention for high- and intermediate-risk..

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Impact of Extracorporeal Membrane Oxygenation Bridging Duration on Lung Transplant Outcomes

Abstract Background We sought to characterize the association between venovenous  (VV-ECMO) bridging duration and outcomes in patients listed for . Methods A retrospective observational study was conducted using the Organ Procurement and..

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Left Ventricular Unloading in Extracorporeal Membrane Oxygenation: A Clinical Perspective Derived from Basic Cardiovascular Physiology

Abstract Purpose of Review To present an abridged overview of the literature and pathophysiological background of adjunct interventional left ventricular unloading strategies during veno-arterial extracorporeal membrane oxygenation (V-A ECMO). From..

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Impact of C-reactive Protein on Anticoagulation Monitoring in Extracorporeal Membrane Oxygenation

Abstract Objective To evaluate the impact of inflammation on  monitoring for patients supported with  (ECMO). Design Prospective single-center . Setting University-affiliated tertiary care academic medical center. Participants Adult venovenous and venoarterial ECMO patients..

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The absolute lactate levels versus clearance for prognostication of post-cardiotomy patients on veno-arterial ECMO

Abstract Aims Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving procedure for supporting patients with cardiogenic shock after cardiac surgery. This work aimed to analyse the impact of changes in..

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Prolonged extracorporeal membrane oxygenation in pediatrics: How long did we wait?

Abstract Background In this study, we aimed to evaluate the duration of extracorporeal membrane oxygenation (ECMO) and its effect on outcomes. Also, we sought to identify hospital mortality predictors and..

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Complications during transport of adult patients on extracorporeal membrane oxygenation

Abstract Introduction Transport on extracorporeal membrane oxygenation (ECMO) is a risky and complex procedure. Although most published data support the feasibility of interhospital transport on ECMO, data concerning intra-facility transportation..

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Comprehensive Characterization of Surface-Bound Proteins and Measurement of Fibrin Fiber Thickness on Extracorporeal Membrane Oxygenation Circuits Collected From Patients

Abstract Objective:  To characterize surface-bound proteins and to measure the thickness of fibrin fibers bound to extracorporeal membrane oxygenation (ECMO) circuits used in children. Design:  Single-center observational prospective study, April..

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Retrospective analysis of multi‑drug resistant Gram‑negative bacteria on veno‑venous extracorporeal membrane oxygenation. The multicenter RANGER STUDY

Abstract Background Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a rapidly expanding life-support technique worldwide. The most common indications are severe hypoxemia and/or hypercapnia, unresponsive to conventional treatments, primarily in..

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Extracorporeal Membrane Oxygenation-Supported Patient Outcome Undergoing Transcatheter Aortic Valve Replacement

Abstract The efficacy and safety of extracorporeal membrane oxygenation (ECMO) support during transcatheter aortic valve replacement (TAVR) remains unknown. We conducted a meta-analysis to compare benefit and risk of ECMO..

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Pulse Pressure and Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis

Abstract Low pulse pressure (PP) in venoarterial-extracorporeal membrane oxygenation (VA-ECMO) is a marker of cardiac dysfunction and has been associated with acute brain injury (ABI) as continuous-flow centrifugal pump may..

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Comparison of red blood cell transfusions and hemostatic transfusions and their relation to thromboses in pediatric patients receiving extracorporeal membrane…

Abstract Objective To evaluate the association of RBC transfusions with thrombosis in pediatric patients on extracorporeal membrane oxygenation (ECMO) and compare this with the transfusion of other blood products and..

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Extracorporeal membrane oxygenation becomes a conceptual part of postoperative care after Norwood surgery for single-ventricle patients Get access Arrow

Abstract The authors of the study ‘Outcome after extracorporeal membrane oxygenation therapy in Norwood patients before the bidirectional Glenn operation’ should be congratulated for their very good results of Norwood..

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Comparative analysis of oxygenator dysfunction in polymethylpentene oxygenators: A pilot study

Abstract Introduction Polymethylpentene (PMP) oxygenators serve as the primary oxygenator type utilized for ECMO. With the number of PMP oxygenators available, it has become increasingly important to determine differences among..

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Controlled automated reperfusion of the whole body after cardiac arrest: Device profile of the CARL system

Abstract Background Cardiac arrest is associated with high mortality rates and severe neurological impairments. One of the underlying mechanisms is global ischemia-reperfusion injury of the body, particularly the brain. Strategies..

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Transoesophageal echocardiography in cardiac arrest: From the emergency department to the intensive care unit

Abstract Cardiac arrest is a hyper-acute condition with a high mortality that requires rapid diagnostics and treatment. As such, point-of-care ultrasound (POCUS) has become a valuable tool in the assessment..

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Should Obesity Be an Exclusion Criterion for Extracorporeal Membrane Oxygenation Support? A Scoping Review

Abstract Obesity is often considered a contraindication to extracorporeal membrane oxygenation (ECMO) candidacy due to technical challenges with vascular access, higher cardiac output requirements, and known associations between obesity and..

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Organ Donation from Patients Receiving Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract Objective The mismatch between the demand for and supply of organs for transplantation is steadily growing. Various strategies have been incorporated to improve the availability of organs, including organ..

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Extracorporeal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction

Abstract Despite multimodal treatment of patients with  (CS) complicating  (AMI), the outcome remains poor. Large retrospective analyses and animal models suggest that  (ECLS) in CS-complicating AMI improves outcome . However, to date, no  assessing the..

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