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The Ventilatory Ratio as a Predictor of Successful Weaning from a Veno-Venous Extracorporeal Membrane Oxygenator

Abstract Background:  Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a critical intervention for patients with severe lung failure, especially acute respiratory distress syndrome (ARDS). The weaning process from ECMO relies largely..

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Safety and feasibility of conversion from venoarterial to venovenous extracorporeal membrane oxygenation in pediatric patients: A case series

Abstract Introduction In children requiring venoarterial (VA) extracorporeal membrane oxygenation (ECMO) for long durations, conversion to venovenous (VV) support may be advantageous. The purpose of this study was to evaluate..

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Post-Cardiac Arrest Care in Extracorporeal Cardiopulmonary Resuscitation

Abstract OBJECTIVES: Extracorporeal cardiopulmonary resuscitation (ECPR) serves as a lifesaving intervention for patients experiencing refractory cardiac arrest. With its expanding usage, there’s a burgeoning focus on improving patient outcomes through..

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“Awake” Cannulation of Patients for Venovenous Extracorporeal Membrane Oxygen: An Analysis of the Extracorporeal Life Support Organization Registry

Abstract IMPORTANCE:  “Awake” cannulation for venovenous extracorporeal membrane oxygenation (ECMO), where patients remain spontaneously breathing without invasive mechanical ventilation during the cannulation procedure, may reduce lung injury from positive pressure..

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CIRBP Aggravation of Cardiac Fibrosis after Myocardial Infarction during ECMO Assistance

Abstract Background: Cold-induced RNA binding protein (CIRBP) is widely involved in critical physiological processes of myocardial fibrosis (MF), a crucial mechanism of cardiac insufficiency in myocardial infarction (MI). However, whether CIRBP..

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Systemic Inflammatory Responses in ECMO-Treated Patients: A Systematic Reviews and Meta-Analysis

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is associated with significant inflammatory reactions that can impact patient outcomes. This meta-analysis aimed to evaluate the impact of ECMO on the functional ability of..

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Hemodynamic Effect of Hydroxocobalamin During Extracorporeal Membrane Oxygenation

Abstract Background: Hydroxocobalamin increases systemic blood pressure through nitric oxide pathway suppression. However, its effects on hypotension during extracorporeal membrane oxygenation (ECMO) are unknown. The objective of this study was to..

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The Impact of Cannulation Sites on Post-Cardiotomy ECMO Outcomes

Abstract Introduction: Although post-cardiotomy extracorporeal membrane oxygenation (ECMO) is associated with high mortality1, the impact of cannulation site is poorly understood. Methods: We conducted a retrospective review of our post-cardiotomy veno-arterial ECMO..

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Cardiopulmonary bypass and VA-ECMO induced immune dysfunction: common features and differences, a narrative review

Abstract Cardiopulmonary bypass (CPB) and veno-arterial extracorporeal membrane oxygenation are critical tools in contemporary cardiac surgery and intensive care, respectively. While these techniques share similar components, their application contexts differ,..

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Molecular Hydrogen and Extracorporeal Gas Exchange: A Match Made in Heaven? An In Vitro Pilot Study

Abstract Extracorporeal circulation (ECC) is frequently implemented in a vast array of modalities such as hemodialysis, cardiopulmonary bypass, extracorporeal membrane oxygenation (ECMO), and others. Patients receiving any such therapy are..

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Adult ECMO Re-cannulation: Fruitful or Futile?

Abstract Introduction: Although decannulation from ECMO is usually irrevocable, in rare circumstances, ECMO will be reinitiated. Data on outcomes after re-cannulation of ECMO are limited,1 so we studied our experience with ECMO..

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Hospital-level volume in extracorporeal membrane oxygenation cases and death or disability at 6 months

Abstract Objective Extracorporeal membrane oxygenation (ECMO) is a high-risk procedure with significant morbidity and mortality and there is an uncertain volume-outcome relationship, especially regarding long-term functional outcomes. The aim of..

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Escalation from IABP to ECMO is associated with increased mortality in patients undergoing VA-ECMO

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used for refractory cardiogenic shock (CS). Although guidelines have downgraded the recommendations for intra-aortic balloon pump (IABP) in CS, escalation from..

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Predictors of Neurologic Complications and Neurodevelopmental Outcome in Pediatric Cardiac Surgery With Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) has emerged as an important intervention for children both preceding and following cardiac surgery. There is a notable lack of comprehensive information regarding neurodevelopmental outcomes...

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VA-ECMO as a Bridge to Recovery in Refractory Circulatory Failure due to Bupropion Overdose

Abstract We present a case of successfully treating an adult woman with a lethal bupropion overdose with VA-ECMO. The patient presented to the hospital with severe encephalopathy, which progressed to..

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Using machine learning to predict neurologic injury in venovenous extracorporeal membrane oxygenation recipients: An ELSO Registry analysis

Abstract Background Venovenous extracorporeal membrane oxygenation (VV-ECMO) is associated with acute brain injury (ABI), including central nervous system (CNS) ischemia (defined as ischemic stroke or hypoxic-ischemic brain injury [HIBI]) and..

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Unraveling the Blood Biomaterial Interaction During Extracorporeal Membrane Oxygenation

Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports. The utilization..

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Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults

Abstract When native blood flow through the aorta from the adult heart and lungs meets retrograde blood flow from an artificial heart and lung during venoarterial extracorporeal membrane oxygenation (VA-ECMO),..

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Factors Influencing Successful Weaning From Venoarterial Extracorporeal Membrane Oxygenation: A Systematic Review

Abstract With advancements in  (ECLS) technologies, venoarterial  (VA-ECMO) has emerged as a crucial cardiopulmonary support mechanism. This review explores the significance of VA-ECMO system configuration,  strategies, and timing of initiation. Through an analysis..

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High Risk ECMO Cannula to Circuit Connection

Abstract A patient with a percutaneously inserted cardiopulmonary bypass cannula into the right internal jugular vein, connected to an extracorporeal membrane oxygenation (ECMO) circuit using tape, was referred for transport..

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Extracorporeal membrane oxygenation support in adult patients: Comparing COVID-19- and non-COVID-19-associated respiratory failure

Abstract Introduction Extracorporeal membrane oxygenation (ECMO) is a vital intervention for acute respiratory distress syndrome (ARDS), yet its efficacy with coronavirus disease 2019 (COVID-19) remains unknown. This study compared the..

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Post-discharge health-related quality of life, cognitive function, disability, risk of post-traumatic stress disorder, and depression amongst the survivors of veno-venous…

Abstract Background Veno-venous extra-corporeal membrane oxygenation (VV-ECMO) is a form of mechanical respiratory support for critically ill patients with severe acute respiratory distress syndrome (ARDS). Using a large intravenous line in..

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Ultra-Low-Field Portable MRI and Extracorporeal Membrane Oxygenation: Preclinical Safety Testing

Abstract CONTEXT:  Conventional MRI is incompatible with extracorporeal membrane oxygenation (ECMO) cannulas and pumps. Ultra-low-field portable MRI (ULF-pMRI) with 0.064 Tesla may provide a solution, but its safety and compatibility..

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Implementation of a novel retrograde implantation technique for distal limb perfusion during extracorporeal cardiopulmonary resuscitation

Abstract In recent decades, the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has increased. In acute cardiogenic shock, VA-ECMO implantation can serve as a bridging solution to facilitate recovery, provide..

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Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction

Abstract Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group [, ]...

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Systematic Review of Ex Vivo and In Vivo Pharmacokinetic Studies of Drugs Commonly Used During Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is a lifesaving treatment for critically ill patients in cardiac or respiratory failure refractory to conventional treatment. Patients on an ECMO circuit (pump, oxygenator, tubing)..

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Awake VA-ECMO: Patient characteristics and outcomes from a single center experience

Abstract Background: Veno-Arterial Extracorporeal membrane oxygenation (VA-ECMO) provides temporary cardiopulmonary support in the setting of refractory cardiogenic shock. Mechanical ventilation and sedation often accompanies VA-ECMO support and carry the increased risk..

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Association Between Tidal Volume in Invasive Mechanical Ventilation and Mortality in Children With Extracorporeal Membrane Oxygenation

Abstract Mechanical ventilation (MV) strategies in children on extracorporeal membrane oxygenation (ECMO) have not been studied much and the ventilatory parameters to avoid greater lung damage are still unclear. Our..

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My echo checklist in venoarterial ECMO patients

Abstract Transthoracic echocardiography is an essential tool for the management of venoarterial extracorporeal membrane oxygenation (VA-ECMO). Its ease of access makes it ideally suited for routine daily bedside assessments, which..

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HeartMate III Autonomy Assistant in a Hemiplegic Left Ventricular Assist Device Patient: A Case Report

Abstract Terminal heart failure presents challenges, requiring cardiac transplantation, or mechanical circulatory support. Limited donor organ availability has made mechanical support crucial. Advances in centrifugal-flow systems, compared to axial-flow, have..

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