Archives

Perfusfind S.L.

Abstract Contact of blood with artificial surfaces triggers platelet activation. The aim was to compare platelet kinetics after venovenous extracorporeal membrane oxygenation (V-V ECMO) start and after system exchange in..

Perfusfind S.L.

Abstract In blood extracorporeal circulations such as hemodialysis (HD) and extracorporeal membrane artificial lung (ECMO) during the surgical operation, the real-time and noninvasive prediction of heparin concentration c is necessary over the..

Perfusfind S.L.

Abstract This study presents the utilization of a novel, highly lipophilic nitric oxide (NO) donor molecule, S-nitroso-1-adamantanethiol (SNAT), for developing an NO-emitting polymer surface aimed at preventing thrombus formation and bacterial..

Perfusfind S.L.

Abstract The blood vessel network transfers gas and nutrients throughout the body. In addition, vascular cells contribute to essential functions such as coagulation, immune regulation, angiogenesis and tissue repair, and..

Perfusfind S.L.

Abstract BACKGROUND: Andexanet alfa (andexanet) is the only Food and Drug Administration–approved antidote for direct FXa (factor Xa) inhibitors but has been reported to cause resistance to unfractionated heparin (UFH)...

Perfusfind S.L.

Abstract Intraoperative cell salvage (IOCS) allows the collection, treatment, and retransfusion of shed blood from the surgical field and cardiopulmonary bypass (CPB) collector during cardiac surgery. This technique has been..

Perfusfind S.L.

Abstract Background Cardiac surgery patients are at increased risk for venous thromboembolism (VTE). Prevention is the most critical strategy to reduce VTE-associated morbidity and death. However, there is a lack..

Perfusfind S.L.

Abstract Introduction There is no consensus on the dose of heparin to be used intraoperatively in cardiac myxomas, so the goal of this study was to look into the differences..

Perfusfind S.L.

Abstract Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) is associated with the transient activation of a systemic inflammatory response. Fibronectin (FN), an endogenous inflammatory mediator, is a key..

Perfusfind S.L.

Abstract Background: Monitoring the anticoagulant effect of unfractionated heparin (UFH) in extracorporeal membrane oxygenation (ECMO) patients is complex but critically important to balance the risks of treatment related bleeding and..

Perfusfind S.L.

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) is a complex, life-saving procedure that uses mechanical support for patients with refractory cardiac arrest, representing the pinnacle of extracorporeal membrane oxygenation (ECMO) applications. Effective..

Perfusfind S.L.

Abstract Objective To document the experience with ECMO therapy in healthcare institutions across Latin America between 2016 and 2020. Design Cross-sectional study. Setting Private and public health institutions from 7..

Perfusfind S.L.

Abstract The term heparin resistance is likely best defined as the failure of an appropriate dose of unfractionated heparin (UFH) to achieve a predetermined level of anticoagulation. Unfortunately, and despite..

Perfusfind S.L.

Abstract Purpose of review Circulatory and respiratory support with extracorporeal membrane oxygenation (ECMO) has gained widespread acceptance during high-end thoracic surgery. The purpose of this review is to summarize the..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) is mainly used for support of patients with cardiopulmonary collapse. The increasing use of ECMO has shown promising outcomes; however, it still carries the..

Perfusfind S.L.

Abstract Extracorporeal Membrane Oxygenation (ECMO) has become an essential lifesaving intervention for individuals with severe cardiovascular and respiratory failure. Its application is expanding across several therapeutic contexts, surpassing conventional indications...

Perfusfind S.L.

Abstract Background Patients with severe acute respiratory distress syndrome (ARDS) show a high mortality rate of up to 60 %. In such cases, extracorporeal membrane oxygenation (ECMO) support is often required,..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation in a venovenous configuration (VV-ECMO) is increasingly recognized as an important therapeutic option for patients with severe acute respiratory distress syndrome (ARDS). Accumulating scientific evidence as well..

Perfusfind S.L.

Abstract BACKGROUND  Cardiac surgery involving cardiopulmonary bypass (CPB) is associated with the risk of acquired coagulopathy, including dysregulated fibrinolysis, which can result in life-threatening bleeding complications. Aprotinin, an antifibrinolytic agent,..

Perfusfind S.L.

Abstract The currently available point-of-care hemostasis tests are burdened by criticisms concerning the use of different activators and inhibitors and the lack of dynamic flow. These operating conditions may constitute..

Perfusfind S.L.

Abstract Objectives:  To test feasibility of a randomized controlled trial (RCT) with an endpoint of time at goal anticoagulation in children on extracorporeal membrane oxygenation (ECMO) randomized to receive bivalirudin..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) provides temporary cardiorespiratory support for neonatal, pediatric, and adult patients when traditional management has failed. This lifesaving therapy has intrinsic risks, including the development of..

Perfusfind S.L.

Abstract Anticoagulation is an essential component of optimal extracorporeal membrane oxygenation (ECMO) management. Unfractionated heparin is still the anticoagulant of choice in most centers due to longstanding familiarity with the..

Perfusfind S.L.

Abstract Introduction Veno-venous extracorporeal membrane oxygenation has increasingly been utilized to support patients in respiratory failure as a bridge to recovery or lung transplantation. As patients progress from cannulation to..

Perfusfind S.L.

Abstract Pediatric extracorporeal membrane oxygenation (ECMO) provides lifesaving cardiopulmonary support for patients with a multitude of clinical diagnoses, resulting from cardiac and/or respiratory failure refractory to conventional supports (). The..

Perfusfind S.L.

Abstract BACKGROUND  Patients with severe traumatic brain injury (TBI) are at an increased risk of respiratory failure refractory to traditional therapies. The safety of extracorporeal membrane oxygenation (ECMO) in this..

Perfusfind S.L.

Abstract Background: Individuals undergoing cardiac surgery face an increased risk of bleeding, as well as alterations in biochemical and coagulation patterns. Therefore, assessing the effectiveness of systems such as Cell..

Perfusfind S.L.

Abstract Direct oral anticoagulants (DOACs) are increasingly being used due to their improved efficacy/safety ratio and lower clinical and economic burden when compared to vitamin K antagonists. However, bleeding is..

Perfusfind S.L.

Abstract Background Cerebral microbleeds (CMBs) are common and varied in patients receiving extracorporeal membrane oxygenation (ECMO). Here, the authors describe CMB findings in patients receiving ECMO and their association with..

Perfusfind S.L.

Abstract Protamine sulfate is a standard agent used to reverse heparin anticoagulation during cardiovascular procedures such as coronary artery bypass grafting (CABG). Although rare, it can be associated with severe..