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Escalation from IABP to ECMO is associated with increased mortality in patients undergoing VA-ECMO

Abstract Background: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) has been increasingly used for refractory cardiogenic shock (CS). Although guidelines have downgraded the recommendations for intra-aortic balloon pump (IABP) in CS, escalation from..

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Implementation of a novel retrograde implantation technique for distal limb perfusion during extracorporeal cardiopulmonary resuscitation

Abstract In recent decades, the use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has increased. In acute cardiogenic shock, VA-ECMO implantation can serve as a bridging solution to facilitate recovery, provide..

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Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction

Abstract Cardiogenic shock is a critical condition that affects up to 10% of patients hospitalized with acute myocardial infarction (AMI), representing the primary cause of death in this group [, ]...

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Awake VA-ECMO: Patient characteristics and outcomes from a single center experience

Abstract Background: Veno-Arterial Extracorporeal membrane oxygenation (VA-ECMO) provides temporary cardiopulmonary support in the setting of refractory cardiogenic shock. Mechanical ventilation and sedation often accompanies VA-ECMO support and carry the increased risk..

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Acquired antithrombin deficiency in adult patients with postcardiotomy extracorporeal membrane oxygenation

Abstract Introduction This study aimed to investigate the relationship between acquired antithrombin deficiency in patients undergoing postcardiotomy extracorporeal membrane oxygenation (PC-ECMO) and thromboembolic or haemorrhagic events such as bleeding, peripheral..

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Early endothelial injury in cardiogenic shock patients on venoarterial ECMO

Abstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support. Yet, few data are avail-able to support..

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Hemodynamic Effects and Clinical Outcomes of Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO) in Cardiogenic Shock

Abstract Background: Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) is a novel mechanical cardiocirculatory support strategy that provides robust cardiocirculatory support and simultaneous left and right atrial venting via a multi-fenestrated..

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Potential Impact of Direct Versus Indirect Central Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) Cannulation in Refractory Postcardiotomy Cardiogenic Shock

Abstract Background Central venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly employed strategy to support patients in refractory postcardiotomy cardiogenic shock (RPCS). This support can be provided using either indirect..

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Evaluating the Use of Unfractionated Heparin with Intra-Aortic Balloon Counterpulsation

Abstract Background Evidence supporting  with unfractionated heparin (UFH) in patients with an intra-aortic balloon pump (IABP) to prevent  remains limited, while bleeding risks remain high. Monitoring heparin in this setting with anti-factor..

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Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation

Abstract Purpose: Patients receiving venoarterial extracorporeal membrane oxygenation (VA‑ECMO) frequently develop arte‑rial hyperoxaemia, which may be harmful. However, lower oxygen saturation targets may also lead to harmful episodes of hypoxaemia...

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Early endothelial injury in cardiogenic shock patients on venoarterial ECMO

Abstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support [1, 2]. Yet, few data are avail-able..

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Aortic Dissection in a Neonate Receiving Extracorporeal Life Support Therapy: A Case Report

Abstract Extracorporeal life support (ECLS) therapy is increasingly being used to support children with refractory cardiorespiratory failure, but its use is occasionally associated with complications. Neonatal aortic dissection in association..

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Management of cardiogenic shock: state-of-the-art

Abstract The management of cardiogenic shock is an ongoing challenge. Despite all efforts and tremendous use of resources, mortality remains high. Whilst reversing the underlying cause, restoring/maintaining organ perfusion and..

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Left Ventricular Unloading in Extracorporeal Membrane Oxygenation: A Clinical Perspective Derived from Basic Cardiovascular Physiology

Abstract Purpose of Review To present an abridged overview of the literature and pathophysiological background of adjunct interventional left ventricular unloading strategies during veno-arterial extracorporeal membrane oxygenation (V-A ECMO). From..

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The absolute lactate levels versus clearance for prognostication of post-cardiotomy patients on veno-arterial ECMO

Abstract Aims Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving procedure for supporting patients with cardiogenic shock after cardiac surgery. This work aimed to analyse the impact of changes in..

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10 Critical TOE Findings in Cardiogenic Shock: Essential Knowledge for Intensive Care

Introduction: Picture this: You're standing at the bedside of a critically ill patient in the ICU, their life hanging by a thread as cardiogenic shock takes hold. The monitors are..

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Protocolised Management of Cardiogenic Shock and Shock Teams: A Narrative Review

Abstract Despite advances in therapy, the incidence of cardiogenic shock continues to increase, with significant mortality that has improved minimally over time. Treatment options for cardiogenic shock are complex and..

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Are mechanical circulatory supports the forgotten aspect in the implementation of therapies for heart failure?

Abstract Heart failure (HF) is a frequent and severe condition. It is estimated that one in four patients will die within a year following hospitalization for acute decompensation, with significant..

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Pulse Pressure and Acute Brain Injury in Venoarterial Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis

Abstract Low pulse pressure (PP) in venoarterial-extracorporeal membrane oxygenation (VA-ECMO) is a marker of cardiac dysfunction and has been associated with acute brain injury (ABI) as continuous-flow centrifugal pump may..

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The American Association for Thoracic Surgery (AATS) 2024 expert consensus document: Management of neonates and infants with Ebstein anomaly

Abstract Objectives Symptomatic neonates and infants with Ebstein anomaly (EA) require complex management. A group of experts was commissioned by the American Association for Thoracic Surgery to provide a framework..

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Extracorporeal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction

Abstract Despite multimodal treatment of patients with  (CS) complicating  (AMI), the outcome remains poor. Large retrospective analyses and animal models suggest that  (ECLS) in CS-complicating AMI improves outcome . However, to date, no  assessing the..

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Venoarterial Extracorporeal Membrane Oxygenation for Cardiopulmonary Support: Insights From a German Registry

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) support is a lifesaving tool in cardiovascular care, providing excellent hemodynamic assistance for numerous indications, such as cardiogenic shock or periprocedural support in patients..

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Extracorporeal life support during cardiac arrest and cardiogenic shock: a systematic review and meta-analysis

Abstract Purpose Veno-arterial extracorporeal life support (ECLS) is increasingly used in patients during cardiac arrest and cardiogenic shock, to support both cardiac and pulmonary function. We performed a systematic review..

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Unloading in cardiogenic shock: the rationale and current evidence

Abstract Purpose of review  Discussing the rationale and current evidence for left ventricular unloading in cardiogenic shock. Recent findings  Microaxial flow pumps (MFP) and intra-aortic balloon pumps (IABP) augment cardiac..

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Design and principle of operation of the HeartMate PHP (percutaneous heart pump)

Abstract The HeartMate PHP (percutaneous heart pump) is a second-generation transcatheter axial flow circulatory support system. The collapsible catheter pump is inserted through a 14 Fr sheath, deployed across the..

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Routine venoarterial extracorporeal membrane oxygenation for acute myocardial infarction-related cardiogenic shock: what we know and don’t know

Abstract Acute myocardial infarction-related cardiogenic shock (AMI-CS) carries a dismal prognosis. Short-term mortality is in the range of 40–50% []. Until recently, only treatment of the culprit lesion by percutaneous..

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Step by step daily management of short-term mechanical circulatory support for cardiogenic shock in adults in the intensive cardiac care…

Abstract The use of mechanical circulatory support using percutaneous ventricular assist devices (pVAD) has increased rapidly during the last decade without substantial new evidence for their effect on outcome. In..

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Joint EAPCI/ACVC expert consensus document on percutaneous ventricular assist devices

Abstract There has been a significant increase in the use of short-term percutaneous ventricular assist devices (pVADs) as acute circulatory support in cardiogenic shock and to provide haemodynamic support during..

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Features and outcomes of female and male patients requiring postcardiotomy extracorporeal life support

Abstract Objectives Although cardiogenic shock requiring extracorporeal life support after cardiac surgery is associated with high mortality, the impact of sex on outcomes of postcardiotomy extracorporeal life support remains unclear..

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Sex differences in treatments and outcomes of patients with cardiogenic shock: a systematic review and epidemiological meta-analysis

Abstract Background Women are at higher risk of mortality from many acute cardiovascular conditions, but studies have demonstrated differing findings regarding the mortality of cardiogenic shock in women and men...

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