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Outcomes of ECMO as a Bridge to Cardiac Surgery

Abstract Introduction: Although outcomes of post-cardiotomy extracorporeal membrane oxygenation (ECMO) are well studied1, the outcomes of patients bridged to cardiac surgery with ECMO are less well understood. We undertook this study..

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Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery

Abstract Objectives To assess microvascular reactivity during a skin thermal challenge early post-cardiac surgery and its association with outcomes. Design Noninvasive physiological study. Setting Thirty-five-bed department of intensive care. Participants..

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Different ECLS Pump Configurations for Temporary Right Ventricular Assist Device in LVAD Patients: A Retrospective Case–Control Study

Abstract Background: Acute right ventricular failure is a critical complication after left ventricular assist device (LVAD) implantation, often managed with a temporary paracorporeal right ventricular assist device (RVAD). This study..

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Perfusionist education in Japan: A survey of challenges and current status

Abstract Introduction This study aimed to examine the educational challenges faced by perfusionists in Japan. Although Japan has over 400 cardiovascular surgery centers, it performs fewer surgeries than by countries..

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A narrative review on antimicrobial dosing in adult critically ill patients on extracorporeal membrane oxygenation

Abstract The optimal dosing strategy of antimicrobial agents in critically ill patients receiving extracorporeal membrane oxygenation (ECMO) is unknown. We conducted comprehensive review of existing literature on effect of ECMO..

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Effect of nitric oxide delivery via cardiopulmonary bypass circuit on postoperative oxygenation in adults undergoing cardiac surgery (NOCARD trial): a…

Abstract BACKGROUND  Cardiac surgery involving cardiopulmonary bypass induces a significant systemic inflammatory response, contributing to various postoperative complications, including pulmonary dysfunction, myocardial and kidney injuries. OBJECTIVE  To investigate the effect..

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Potential Impact of Direct Versus Indirect Central Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) Cannulation in Refractory Postcardiotomy Cardiogenic Shock

Abstract Background Central venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly employed strategy to support patients in refractory postcardiotomy cardiogenic shock (RPCS). This support can be provided using either indirect..

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Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction…

Abstract Study objective The aim of this study was to investigate the efficacy of a two-step patient blood management (PBM) program in red blood cell (RBC) transfusion requirements among patients..

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Definition and management of right ventricular injury in adult patients receiving extracorporeal membrane oxygenation for respiratory support using the Delphi…

Abstract Purpose: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an integral part of the management algorithm of patients with severe respiratory failure refractory to evidence-based conventional treatments. Right ventricular injury (RVI)..

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Evaluation of Point-of-Care-Directed Coagulation Management in Pediatric Cardiac Surgery

Abstract Background Coagulatory alterations are common after pediatric cardiac surgery and can be addressed with point-of-care (POC) coagulation analysis. The aim of the present study is to evaluate a preventive..

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Use of colloids and crystalloids for perioperative clinical infusion management in cardiac surgery patients and postoperative outcomes: a meta-analysis

Abstract Background The optimal fluid management strategy for patients undergoing cardiac surgery was controversial regarding fluid volume and intraoperative fluid types. This study aimed to assess the correlation between colloids..

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Temperature and Neurologic Outcomes in Neonates Undergoing Cardiac Surgery: A Society of Thoracic Surgeons Study

Abstract Background There is significant variability in postoperative neurological injury rates in patients with , with early injuries impacting long-term neurodevelopmental outcomes; therefore, there is an urgent need for identifying effective..

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Is there a role for extracorporeal membrane oxygenation in children with acute liver failure? A retrospective analysis of the Extracorporeal…

Abstract Data describing the use of extracorporeal membrane oxygenation (ECMO) in pediatric acute liver failure (PALF) are scarce. Thus, we aimed to describe the use of ECMO in patients with..

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Nomogram Model for Cardiac Surgery-Associated Acute Kidney Injury Based on Clinical Characteristics Combined with Plasma suPAR

Abstract Objective: Analyze risk factors for cardiac surgery-associated acute kidney injury (CSA-AKI) in adults and establish a nomogram model for CSA-AKI based on plasma soluble urokinase-type plasminogen activator receptor (suPAR) and..

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Evaluation of university and training standards in clinical perfusion, an European-wide survey

Abstract OBJECTIVES Adequate theoretical and practical training of prospective clinical perfusionists is essential for maintaining clinical standards and ensuring patient safety during cardiac surgery procedures. Perfusion schools play a crucial..

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Uncommon and Unfavorable: Heparin-Induced Hyperkalemia

Abstract Case Report A 56-year-old male with a medical history significant for coronary artery disease complicated by non-ST segment elevation myocardial infarction in 2011 (at which time he received a..

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Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates…

Abstract Background The CRUCIAL trial (NCT04217421) is investigating the effect of postnatal and perioperative administration of allopurinol on postoperative brain injury in neonates with critical congenital heart disease (CCHD) undergoing..

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Tuscany Normothermic Regional Perfusion Mobile Teams for Controlled Donation After Circulatory Death

Abstract Introduction To facilitate the implementation of controlled donation after circulatory death (cDCD) programs even in hospitals not equipped with a local extracorporeal membrane oxygenation (ECMO) team, some countries have..

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Effect of preoperative autologous platelet-rich plasmapheresis on postoperative bleeding in patients undergoing heart valve surgery

Abstract Background: Cardiovascular surgeries often require deep hypothermic circulatory arrest and cardiopulmonary bypass (CPB), which can disrupt blood clotting and lead to excessive bleeding. Traditional treatments involve transfusing blood and blood..

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Heparin-Bead Extraction Enhanced Fluorogenic Aptamer–Thrombin Composite Reporter Enables Sensitive and Rapid Detection of Functional Antithrombin

Abstract Antithrombin (AT) deficiency in the extracorporeal circulation during cardiac surgery leads to uncontrolled inflammation and vascular damage in patients. AT levels decrease in sepsis, major trauma, extracorporeal membrane oxygenation,..

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Non-Contact Measurement of Blood Oxygen Saturation Using Facial Video Without Reference Values

Abstract The continuous measurement of percutaneous oxygen saturation (SpO2) enables diseases that cause hypoxemia to be detected early and patients’ conditions to be monitored. Currently, SpO2 is mainly measured using..

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Is it time for the death knell of single-unit plasma?

Abstract Background and Objectives A plasma transfusion dose should be weight-based (10–20 mL/kg), which equates to three to four units in an average-sized adult; therefore, the transfusion of single units under..

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Electrical impedance tomography during open heart surgery and on the cardiac icu is feasible to monitor ventilation in children with…

Abstract Alveolar de recruitment is a common problem during general anesthesia and operations. Pediatric cardiac surgery with cardiopulmonary Bypass is associated with interruption of ventilation and might enhance loss of..

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Variability and relative contribution of surgeon- and anesthesia-specific time components to total procedural time in cardiac surgery

Abstract Background Decreasing variability in time-intensive tasks during cardiac surgery may reduce total procedural time, lower costs, reduce clinician burnout, and improve patient access. The relative contribution and variability of..

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Year in review: tips for effective graduate medical education programme leadership and management

Abstract Programme leaders in graduate medical education (GME) are responsible for the final stage of physician training, guiding the transition from supervised to independent practice. The influence of GME programme..

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Impact of timing of urgent coronary artery bypass grafting following coronary angiography on acute kidney injury

Abstract Objectives Prior studies have examined the association between timing of cardiac surgery after  with risk of , but this remains controversial. The purpose of this study was to investigate the association..

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Associations Between Nonanemic Iron Deficiency and Postoperative Outcomes in Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract BACKGROUND: Preoperative screening for iron deficiency is a part of patient blood management protocols. This systematic review, meta-analysis, and meta-regression reviews the association between nonanemic iron deficiency and postoperative..

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A clinical comparison of glycol and water-based heater-cooler systems for cardiopulmonary bypass

Abstract Introduction While newer heater-cooler technologies using ethylene glycol-based (GB) solutions during cardiothoracic surgery have become commercially available, there is a paucity of clinical data describing their effectiveness during cardiopulmonary..

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Toward an Adjustable Blood Pump for Wide-Range Operation: In-Vitro Results of Performance Curve and Hydraulic Efficiency

Abstract Rotary blood pumps in Extracorporeal Life Support (ECLS) applications are optimized for a specific design point. However, in clinical practice, these pumps are usually applied over a wide range..

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Antepartum hemorrhage due to placenta previa with autologous transfusion: A case report

Abstract Introduction and importance Bleeding during pregnancy or during  can cause significant morbidity and mortality for the mother and baby, this can be overcome by performing a  (C-section) and . Although blood transfusions..

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