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Anticoagulation management during veno-venous ECMO support because of ARDS: Single-center experience

Abstract Background Patients with severe acute respiratory distress syndrome (ARDS) show a high mortality rate of up to 60 %. In such cases, extracorporeal membrane oxygenation (ECMO) support is often required,..

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Anticoagulation in Extracorporeal Membrane Oxygenation for Trauma: Striking a Balance

Abstract Extracorporeal membrane oxygenation in a venovenous configuration (VV-ECMO) is increasingly recognized as an important therapeutic option for patients with severe acute respiratory distress syndrome (ARDS). Accumulating scientific evidence as well..

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A Guide to Contrast-Enhanced Computed Tomography in Adult Patients Supported With Extracorporeal Membrane Oxygenation

Abstract Veno-arterial extracorporeal membrane oxygenation (VA ECMO) fundamentally alters patient physiology and blood flow relevant to contrast delivery for computed tomography (CT) imaging. Here, we present a comprehensive guide to..

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Minimizing Acute Kidney Injury in Pediatric Cardiac Surgery: Incidence, Early Detection, and Preemptive Measures

Abstract Background Acute kidney injury (AKI) poses a significant challenge in pediatric cardiac surgery, having a profound impact on patient morbidity and mortality. This study aims to determine the incidence..

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Thrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery

Abstract Thrombin generation (TG) is reduced after cardiac surgery using cardiopulmonary bypass (CPB), contributing to coagulopathy and bleeding. Plasma transfusion or four-factor prothrombin complex concentrate (PCC) are commonly used to..

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MiECC reloaded

Abstract The concept of mini cardiopulmonary bypass (mini-CPB) has been introduced in clinical practice from early 2000 for advancing perfusion technology aiming to improve cardiac surgical results. The diversity of custom-made..

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Impact of macrohemodynamic manipulations during cardiopulmonary bypass on finger microcirculation assessed by photoplethysmography signal components

Abstract Objective.  Continuous monitoring of the hemodynamic coherence between macro and microcirculation is difficult at the bedside. We tested the role of photoplethysmography (PPG) to real-time assessment of microcirculation during..

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A model for predicting AKI after cardiopulmonary bypass surgery in Chinese patients with normal preoperative renal function

Abstract Objective To develop and validate a predictive model for acute kidney injury (AKI) after cardiopulmonary bypass (CPB) surgery in Chinese patients with normal preoperative renal function. Method From January..

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The association between changes in cerebral hemodynamics and cerebrovascular complications during ECMO treatment in neonates

Abstract Objective To investigate whether changes in cerebrovascular hemodynamic parameters during extracorporeal membrane oxygenation (ECMO) treatment in neonates are associated with the occurrence of cerebrovascular complications. Methods This study selected..

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The early decline in platelet count is associated with increased adverse outcomes in non heparin-induced thrombocytopenia pediatric patients undergoing VA-ECMO

Abstract Introduction The impact of non heparin-induced thrombocytopenia on the clinical outcomes for pediatric cardiac surgery patients who required veno-arterial extracorporeal membrane support (VA-ECMO) for failure to wean from cardiopulmonary..

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Hemostatic Outcome Definitions in Pediatric Extracorporeal Membrane Oxygenation: Challenges in Cohorts From Rotterdam (2019–2023) and Melbourne (2016–2022)

Abstract Objectives:  To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed..

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Platelet-sparing properties of aprotinin

Abstract BACKGROUND  Cardiac surgery involving cardiopulmonary bypass (CPB) is associated with the risk of acquired coagulopathy, including dysregulated fibrinolysis, which can result in life-threatening bleeding complications. Aprotinin, an antifibrinolytic agent,..

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Use of extracorporeal blood purification therapies in sepsis: the current paradigm, available evidence, and future perspectives

Abstract Background Sepsis is the result of a dysregulated immune response to infection and is associated with acute organdysfunction. The syndrome’s complexity is contingent upon the underlying pathology and individual..

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Current status of routine use of veno-arterial extracorporeal membrane oxygenation during lung transplantation

Abstract Introduction Recently, there has been growing experience with utilizing a veno-arterial extracorporeal membrane oxygenator (VA ECMO) routinely during lung transplantation procedures. Yet, there is a lack of consensus on..

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Early extracorporeal membranous oxygenation and burn excision in severe burn and inhalation injury

Abstract Introduction Extracorporeal membranous oxygenation (ECMO) as a salvage therapy for patients with severe acute respiratory distress syndrome (ARDS) has been described but experience is limited in burn cases. Few..

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ECMO-weaning facilitated by neurally adjusted ventilatory assist (NAVA): a case for principal clarification

Abstract The use of veno-venous extracorporeal membrane oxygenation (VV-ECMO) has become increasingly prevalent, particularly in respiratory disease pandemics such as H1N1-influenza and SARS-CoV-2. This surge has emphasized the importance of..

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Total reversal of the pulmonary circulation (RPC) induced by peripheral cannulation for veno-arterial ECMO in a patient with aortic and…

Abstract This case report details a rare instance of total reversal of the pulmonary circulation (RPC) in a 56-year-old male patient on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) during emergency..

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Pulse Pressure During VA-ECMO Support and Neurologic Outcomes: Worth Getting Pumped Up About?

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for the management of refractory cardiogenic shock. Although VA-ECMO can stabilize hemodynamics and improve systemic flow, morbidity, and mortality on support..

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Outcomes of Del Nido and hyperkalemic blood cardioplegia in adult cardiac surgery with prolonged aortic cross-clamp times

Abstract Background: The utility and uptake of Del Nido cardioplegia in adult cardiac surgery is rapidly increasing. Cases with prolonged aortic cross-clamp times necessitate multi-dosing however an understanding of safe..

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Pre-Hospital ECPR cost analysis and cost effectiveness modelling study

Abstract Background The use of extracorporeal membrane oxygenation (ECMO) during cardiopulmonary resuscitation (ECPR) is increasing. Prehospital ECPR (PH-ECPR) for out-of-hospital cardiac arrest (OHCA) may improve both equity of access and..

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How we use ultrasound in the management of weaning from mechanical ventilation

Abstract Difficult weaning from invasive mechanical ventilation is associated with adverse clinical outcome and increased use of limited health care resources. Difficult weaning, characterized by failure of multiple spontaneous breathing..

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Comparison of clinical outcomes between double arterial cannulation and single arterial cannulation in type A aortic dissection

Abstract It remains controversial as to which optimal cannulation strategy ought to be employed in surgery for type A aortic dissection (TAAD). The aim of this study was to make..

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Development and Evaluation of a Novel Drainage Cannula for Venoarterial Extracorporeal Membrane Oxygenation

Abstract A critical factor in thrombus formation during venoarterial extracorporeal membrane oxygenation (VA ECMO) is prothrombotic flow dynamics generated by the drainage cannula’s design. This study aimed to create and..

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Chilling Choices: Heart Transplant Outcomes Using SherpaPak With Long Ischemic Time Versus Traditional Ice Storage With Short Ischemic Time

Abstract We performed a retrospective review comparing outcomes between traditional ice storage (ICE) with short ischemic times (<3 hours) to SherpaPak Cardiac Transport System (SCTS) with long ischemic times (>4..

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Exercise and cardiac rehabilitation after LVAD implantation

Abstract Left ventricular assist devices (LVAD) have improved mortality and quality of life for patients with end-stage heart failure by providing an alternative to cardiac transplant or as a bridge..

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Surgical Intraoperative Handoff Initiative: Standardizing Operating Room Communication Using SHRIMPS

BACKGROUND:  Operating room (OR) handoffs are not universally standardized, although standardized sign outs have been proven to provide effective communication in other aspects of healthcare. We hypothesize that creating a..

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Is It Ethically Justifiable to Withdraw Extracorporeal Membrane Oxygenation Against the Wishes of a Patient With Decision-Making Capacity When Cure…

It is well established that clinicians may decline requests for inappropriate interventions, including life-prolonging interventions. This position is supported by major professional organizations,, statutes and regulations, and case law. As such, the open..

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Complexities, Benefits, Risks, and Clinical Implications of Sodium Bicarbonate Administration in Critically Ill Patients: A State-of-the-Art Review

Abstract Sodium bicarbonate has been used in the treatment of different pathologies, such as hyperkalemia, cardiac arrest, tricyclic antidepressant toxicity, aspirin toxicity, acute acidosis, lactic acidosis, diabetic ketoacidosis, rhabdomyolysis, and..

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Rare case presentation of thoracic aortic aneurysm and aortic dissection in adolescent

Abstract Introduction: Familial thoracic aortic aneurysm and aortic dissection (f/TAAD) is a genetic disease defined by disturbance in encoding the major proteins in the smooth muscle cells (SMC) contractile filaments..

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BTT-ECMO Trends and Outcomes Under Revised Heart Allocation System

Abstract Under the revised UNOS heart allocation system, waitlist and post-transplant outcomes among patients bridged to transplant with VA-ECMO (BTT-ECMO) have improved. However, it remains largely unknown if these early..

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