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Bleeding Complications in Patients With Perioperative COVID-19 Infection Undergoing Cardiac Surgery: A Single-Center Matched Case-Control Study

Abstract Objective Previous studies reported a poor outcome in patients with coronavirus 2019 (COVID-19) undergoing cardiac surgery. Complications most frequently described were respiratory failure, renal failure, and thromboembolic events. In..

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The effect of pulsatile versus non-pulsatile flow during cardiopulmonary bypass on cerebral oxygenation: A randomized trial

Abstract Background The present study aims to compare regional oxygen supply determined by Near-Infrared Spectroscopy in the course of pulsatile perfusion with non-pulsatile perfusion during cardiopulmonary bypass in patients undergoing..

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Automatic control of blood flow rate on the arterial-line side during cardiopulmonary bypass

Abstract The operation of the cardiopulmonary bypass (CPB) system requires skilled techniques and experience. Intraoperatively, the perfusionist needs to intermittently manipulate both of the occluders on the venous- and arterial-line..

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Impact of Intraoperative Salvaged Blood Autotransfusion During Obstetric Hemorrhage on the Coagulation Function: A Retrospective Cohort Analysis

Abstract Objective This study aimed to explore the effect of intraoperative blood salvage (autotransfusion) on coagulation function in the rescue of an obstetric hemorrhage. Methods A total of 65 pregnant..

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Liberation From Venoarterial Extracorporeal Membrane Oxygenation: A Review

Abstract Venoarterial extracorporeal membrane oxygenation may be used for circulatory support in cardiogenic shock as a bridge to recovery, a bridge to a ventricular assist device (VAD), or a bridge..

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COVID-19 in the Perioperative Period of Cardiovascular Surgery: the Brazilian Experience

Abstract Introduction We investigated the clinical course and outcomes of patients submitted to cardiovascular surgery in Brazil and who had developed symptoms/signs of coronavirus disease 2019 (COVID-19) in the perioperative..

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Association of Volume Status During Veno-Venous Extracorporeal Membrane Oxygenation with Outcome

Abstract Fluid overload in acute respiratory distress syndrome is associated with increased mortality. The purpose of this study was to investigate the association of cumulative fluid balance (CFB) during the..

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Enhanced Platelet-Rich Plasma (ePRP) Stimulates Wound Healing through Effects on Metabolic Reprogramming in Fibroblasts

Abstract As a source of growth factors for expediting wound healing and tissue regeneration, plasma-rich plasma (PRP) has been extensively applied in diverse fields including orthopaedics, ophthalmology, oral and maxillofacial..

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Extracorporeal membrane oxygenation (ECMO): Radiographic appearances, complications and imaging artefacts for radiologists

Abstract Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary support primarily used in cardiothoracic and intensive care unit (ICU) settings. The purpose of this review is to familiarise radiologists..

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The 7 Pillars of Blood Conservation in Cardiac Surgery

Introduction National health expenditures rose to 3.8 trillion dollars in 2019, 18% of gross domestic product, and are continuing to rise at an unsustainable rate. Aggregate costs for hospitalizations associated with..

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Pulmonary Arterial Hypertension

Abstract Without effective treatment, pulmonary arterial hypertension results in high morbidity and mortality. This review discusses the pathogenesis of the disorder, the thorough clinical evaluation required to establish the diagnosis,..

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Bleeding and Thrombotic Events During Extracorporeal Membrane Oxygenation for Postcardiotomy Shock

Abstract Background  management during venoarterial  (ECMO) is particularly difficult in postcardiotomy shock patients given a significant bleeding risk. We sought to determine the effect of  treatment on bleeding and thrombosis risk for..

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A Technique for Safe Redo Sternotomy in Patients with Aortic Proximity to the Sternum

Abstract The risk of redo sternotomy is greatly elevated in the setting of aortic proximity to the sternum. Current strategies to avoid catastrophic neurologic injury upon sternal reentry include establishment..

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The year in cardiovascular medicine 2021: valvular heart disease

Introduction The increasing burden of valvular heart disease (VHD)—in particular in an ageing population—is recognized by medical experts, although there is less awareness of these conditions by the general public..

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Cannulation Strategy for Extracorporeal Membrane Oxygenation Does Not Influence Total Hospital Cost

Abstract Background The Center for Medicare and Medicaid Services decreased reimbursement rates for peripheral venoarterial (VA)  (ECMO) and venovenous (VV) ECMO procedures in October 2018. Limited data are available describing hospital..

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Target blood pressure management during cardiopulmonary bypass improves lactate levels after cardiac surgery: a randomized controlled trial

Abstract Background Hyperlactatemia is associated with a poor prognosis in cardiac surgery patients. This study explored the impact of target blood pressure management during cardiopulmonary bypass (CPB) on blood lactate..

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Prevention and management of spinal cord ischemia following aortic surgery: A survey of contemporary practice

Abstract Objective  (SCI) is a devastating complication of  repair. We aim to characterize current practices pertaining to SCI prevention and treatment across Canada. Methods Two questionnaires were developed by the Canadian..

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Does supply meet demand? A comparison of perfusion strategies on cerebral metabolism in a neonatal swine model

Abstract Objective We aimed to determine the effects of selective antegrade  compared with other perfusion strategies on indices of cerebral blood flow, oxygenation, cellular stress, and mitochondrial function. Methods One-week-old piglets..

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Treating the Most Critically Ill Patients With COVID-19, The Evolving Role of Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is an advanced, resource-intensive form of life support for patients with severe respiratory or cardiac failure, and is typically provided within specialized centers. Prior to..

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Flow Manipulation and the Association with Myocardial Systolic Function During Extracorporeal Life Support

Abstract Background: Peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) is used to support circulatory failure refractory to conventional therapy.  However, data on the heart-ECMO interaction at different levels of ECMO..

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Pulmonary Transplant After More Than 1 Year of Continuous Ambulatory Extracorporeal Support

Abstract While extracorporeal support of patients awaiting pulmonary transplantation is now well-established, extracorporeal membrane oxygenation (ECMO) remains a nondurable technology deployed for short-term support or recovery in patients with progressive..

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Effect of minimally invasive mitral valve surgery compared to sternotomy on short- and long-term outcomes: a retrospective multicentre interventional cohort…

Abstract   OBJECTIVE Minimally invasive mitral valve surgery (MIMVS) has been performed increasingly for the past 2 decades; however, large comparative studies on short- and long-term outcomes have been lacking...

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Delirium in Children After Cardiac Bypass Surgery

Abstract Background Delirium is acute brain dysfunction associated with serious illness. Emerging data indicate that delirium occurs in greater than 20% of children in pediatric intensive care units. Cardiac bypass..

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A Simple Approach for Minimally Invasive Combined Aortic and Mitral Valve Surgery

Abstract Background  There is now extension of minimally invasive techniques to involve concomitantly aortic and mitral valves through a single small incision. We share our experience in such surgeries through..

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Changes in left ventricular and atrial mechanics and function after dialysis in patients with end-stage renal disease

Abstract Background: Hemodialysis (HD) can influence end-stage renal disease (ESRD) patients’ circulatory system. The present study aimed to evaluate the effect of volume depletion on left ventricular (LV) and left atrial..

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Impact of aortic valve disease on outcomes of aortic root replacement

Abstract Background and Aim of the Study Aortic stenosis (AS) has been associated with higher mortality in patients undergoing aortic root replacement (ARR). In this analysis, we compare the outcomes..

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PHYSIOLOGIC EFFECTS OF CONTINUOUS-FLOW LEFT VENTRICULAR ASSIST DEVICES

Abstract Background Within the past ten years, continuous-flow Left Ventricular Assist Devices (LVADS) have replaced pulsatile-flow LVADs as the standard of care for both destination therapy and bridging patients to..

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Concept and Design of a Novel Pulsatile Left Heart Assist Device—The PERKAT Left Ventricle System

Abstract Cardiogenic shock is associated with high mortality. Patients often require temporary mechanical circulatory support. We aimed to develop a percutaneously implantable, assist device that unloads the left ventricle (LV)..

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Efficacy and safety of ECG-synchronized pulsatile extracorporeal membrane oxygenation in the clinical setting: The SynCor Trial

Abstract Introduction Mechanical circulatory support (MCS) devices are increasingly used as a treatment option in resuscitation or in patients with cardiogenic shock (CS). Prophylactic implantation in high-risk percutaneous coronary interventions..

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Early implementation of renal replacement therapy after lung transplantation does not impair long-term kidney function in patients with idiopathic pulmonary…

Abstract Objectives In patients with idiopathic pulmonary arterial hypertension, cardiac function can be impaired in the early  after  because the chronically untrained  is prone to fail. Thus, restrictive fluid management is pivotal to..

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