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Intraoperative transfusion practices and perioperative outcome in the European elderly: A secondary analysis of the observational ETPOS study

Abstract The demographic development suggests a dramatic growth in the number of elderly patients undergoing surgery in Europe. Most red blood cell transfusions (RBCT) are administered to older people, but..

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Analysis of Dynamic Changes in Cognitive Workload During Cardiac Surgery Perfusionists′ Interactions With the Cardiopulmonary Bypass Pump

Abstract Objective This novel preliminary study sought to capture dynamic changes in heart rate variability (HRV) as a proxy for cognitive workload among perfusionists while operating the cardiopulmonary bypass (CPB)..

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Extracorporeal membrane oxygenation for COVID-19 during first and second waves

Abstract COVID-19 has ravished the world, with secondary consequences that are not yet possible to estimate. WHO and the European Extracorporeal Life Support Organization (ELSO) recommended extracorporeal membrane oxygenation (ECMO)..

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The effect of retrograde autologous priming on intraoperative blood product transfusion in coronary artery bypass grafting

Abstract Introduction: Retrograde autologous priming (RAP) of the cardiopulmonary bypass (CPB) circuit could reduce the degree of haemodilution associated with priming with acellular solutions. However, there is no strong evidence to..

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A mock circulation loop to evaluate differential hypoxemia during peripheral venoarterial extracorporeal membrane oxygenation

Abstract Introduction Peripheral veno-arterial extracorporeal membrane oxygenation (VA ECMO) creates a retrograde flow along the aorta competing with the left ventricle (LV) in the so-called ‘mixing zone’ (MZ). Detecting it..

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ECMO en SDRA: puntos clave en la indicación y en el abordaje asistencial

Abstract El uso de la técnica de oxigenación mediante membrana extracorpórea (ECMO), en su configuración venovenosa (V-V), en pacientes con síndrome de distrés respiratorio agudo (SDRA) ha aumentado en los..

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Utilization of EKOS in Patients With Pulmonary Embolism

Abstract Objective: Current guidelines recommend utilization of catheter-directed thrombolysis systems for management of patients with submassive pulmonary embolism (PE) who have relative contraindications to systemic thrombolysis. Evidence from previous trials have..

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Conventional Versus Minimally Invasive Aortic Valve Replacement Surgery: A Systematic Review, Meta-Analysis, and Meta-Regression

Abstract Objective: To assess the potential benefits of minimally invasive aortic valve replacement (MIAVR) compared with conventional AVR (CAVR) by examining short-term outcomes.  Methods: A systematic search identified randomized trials comparing MIAVR..

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ECMO During Respiratory Pandemics: Past, Present, and Future

Abstract The role of extracorporeal membrane oxygenation (ECMO) in the management of severe acute respiratory failure, including the acute respiratory distress syndrome, has become better defined in recent years in..

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Impact of extracorporeal membrane oxygenation service on burnout development in intensive care units. A national cross-sectional study in eight intensive…

Abstract Objectives This study aimed at investigating the effects of an extracorporeal membrane oxygenation (ECMO) service, on Burnout syndrome (BOS) development in the intensive care unit (ICU). Design We conducted..

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Longitudinal Trends in Bleeding Complications on Extracorporeal Life Support Over the Past Two Decades—Extracorporeal Life Support Organization Registry Analysis

Abstract Objectives:  Data about inhospital outcomes in bleeding complications during extracorporeal life support (ECLS) have been poorly investigated. Design:  Retrospective observational study. Setting:  Patients reported in Extracorporeal Life Support Organization..

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Association of urine output during cardiopulmonary bypass and postoperative acute kidney injury in patients undergoing coronary artery bypass graft

Abstract Introduction Acute kidney injury (AKI) is a common complication in patients undergoing coronary artery bypass graft (CABG) surgery and is associated with significant morbidity and mortality. We investigated the..

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Outcomes by Cannulation Methods for Venovenous Extracorporeal Membrane Oxygenation during COVID-19: A Multicenter Retrospective Study

Abstract Purpose To determine if a cannulation method for venovenous extracorporeal membrane oxygenation (V-V ECMO) is related to patient outcome. Methods A retrospective, multi-center study of adult patients (≥18 years..

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Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital…

Abstract Importance  Out-of-hospital cardiac arrest (OHCA) has poor outcome. Whether intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and immediate invasive assessment and treatment (invasive strategy) is beneficial in this setting remains uncertain...

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Coagulation activation during extracorporeal membrane oxygenation (ECMO)

Abstract Introduction  (ECMO) can be life-saving, but suffers from  in the circuit with associated risks of  occlusion,  and . The formation of thrombin is the key step to thrombus formation and two factors are..

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Impella Management for the Cardiac Intensivist

Abstract The Impella mechanical circulatory support (MCS) system is a catheter-based continuous flow cardiac assist device that is widely used in the treatment of cardiogenic shock in medical and surgical cardiac intensive..

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A review of ECMO for cardiac arrest

Abstract Cardiac arrest is an important public health concern, affecting an estimated 356,500 people in the out-of-hospital setting and 209,000 people in the in-hospital setting each year. The causes of..

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Impact of comorbidities on older patients undergoing open heart surgery

Abstract Background  The number of elderly patients undergoing cardiac surgery is increasing. Age greater than 80 years has been identified as a strong independent risk factor for short- and long-term..

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ECMO in Cardiac Arrest: A Narrative Review of the Literature

Abstract Cardiac arrest (CA) is a frequent cause of death and a major public health issue. To date, conventional cardiopulmonary resuscitation (CPR) is the only efficient method of resuscitation available..

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Combining Heparin and a FX/Xa Aptamer to Reduce Thrombin Generation in Cardiopulmonary Bypass and COVID-19

Abstract Known limitations of unfractionated heparin (UFH) have encouraged the evaluation of anticoagulant aptamers as alternatives to UFH in highly procoagulant settings such as cardiopulmonary bypass (CPB). Despite progress, these..

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High-resolution perioperative cerebral blood flow autoregulation measurement: a practical and feasible approach for widespread clinical monitoring

Abstract A growing body of evidence demonstrates that excursions of BP below or above the limits of cerebral blood flow autoregulation are associated with complications in patients with neurological injury..

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Evaluating the Impact of Cardiopulmonary Bypass Priming Fluids on Bleeding After Pediatric Cardiac Surgery: A Systematic Review and Meta-Analysis

Abstract Objectives Cardiopulmonary bypass (CPB) predisposes young children to coagulopathy. The authors evaluated possible effects of CPB priming fluids on perioperative bleeding in pediatric cardiac surgery. Design Meta-analysis and systematic..

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S100B in cardiac surgery brain monitoring: friend or foe?

Abstract Recent advances in perioperative management of adult and pediatric patients requiring open heart surgery (OHS) and cardiopulmonary bypass (CPB) for cardiac and/or congenital heart diseases repair allowed a significant..

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Morbidity and mortality in patients managed with high compared with low blood pressure targets during on-pump cardiac surgery: a systematic…

Abstract Purpose Many believe that blood pressure management during cardiac surgery is associated with postoperative outcomes. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to determine..

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Reliability of Bioreactance and Pulse-Power Analysis in Measuring Cardiac Index in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objectives Less-invasive and continuous cardiac output monitors recently have been developed to monitor patient hemodynamics. The aim of this study was to compare the accuracy, precision, and trending ability..

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Blood Protection Method: Retrograde Autologous Prime

Blood Protection Method: Retrograde Autologous Prime   In order to carry out open heart surgery, the functions of the heart and lungs must be stopped and the blood inside the..

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Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

Abstract BACKGROUND Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS In an open-label trial with blinded assessment of outcomes,..

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In Vivo Suction Pressures of Venous Cannulas During Veno-venous Extracorporeal Membrane Oxygenation

Abstract Extracorporeal lung support includes the risk of hemolysis due to suction pressures. Manufacturers measure the negative suction pressure across drainage cannulas for their products in vitro using water. Clinical experience suggests..

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Echocardiography in Weaning Right Ventricular Mechanical Circulatory Support: Are We Measuring the Right Stuff?

Abstract Although acute right ventricular (RV) failure is uncommon, it is associated with a poor prognosis and high mortality. A range of devices now exist to provide temporary mechanical circulatory..

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Veno-venous extracorporeal membrane oxygenation (vv-ECMO) for severe respiratory failure in adult cancer patients: a retrospective multicenter analysis

Abstract Purpose: The question of whether cancer patients with severe respiratory failure beneft from veno-venous extracorporeal membrane oxygenation (vv-ECMO) remains unanswered. We, therefore, analyzed clinical characteristics and outcomes of a..

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