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Contributions of Systolic and Diastolic Blood Pressures to Cardiovascular Outcomes in the ALLHAT Study

Abstract Background SBP and DBP have important associations with cardiovascular events, but are seldom considered simultaneously. Objectives This study sought to simultaneously analyze systolic blood pressure (SBP) and diastolic blood..

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Automated and cost-efficient early detection of hemolysis in patients with extracorporeal life support: Use of the hemolysis-index of routine clinical…

Abstract Purpose Patients with  (ECLS) are at risk for hemolysis-related complications. Therefore, monitoring of free hemoglobin (fHb) levels is indicated. Conventional methods for fHb are laborious and not always available. Here..

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No extra COVID-19 risk for ECMO transport teams, reports ASAIO Journal

Abstract Newswise — November 22, 2021 –  – with no increased risk of transmitting COVID-19 transmission to ECMO transport team members following standard precautions, reports a study in the , official journal of..

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Glycemic control is not associated with neurocognitive decline after cardiac surgery

Abstract Background Whether perioperative glycemic control is associated with neurocognitive decline (NCD) after cardiac surgery was examined. Methods Thirty patients undergoing cardiac surgery utilizing cardiopulmonary bypass (CPB) were screened for..

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Nonfinancial conflict of interest in peer-review: Some notes for discussion

Abstract Strong beliefs can influence the way we deal with emotionally charged topics. Researchers, editors, and reviewers are not an exception. Declaring such nonfinancial conflict of interest when handling or..

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Extracorporeal Membrane Oxygenation and Continuous Kidney Replacement Therapy: Technology and Outcomes – A Narrative Review

Abstract The number of patients using critical care is increasing as our populations live longer thanks to advances in medical therapies. This is reflected by an increase in both usage..

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Prognostic value of SARS-CoV-2 on patients undergoing cardiac surgery

Abstract Objective To analyze Italian Cardiac Surgery experience during the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) identifying risk factors for overall mortality according to coronavirus disease 2019..

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Kidney Replacement Therapy for Patients Requiring Cardiopulmonary Bypass Support during Cardiac Surgery

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article..

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Sonoclot Signature Analysis: A New Point-of-Care Testing Method for Defining Heat Stroke-Induced Coagulopathy

Abstract Purpose: Data regarding the incidence of a coagulable state following heat stroke as assessed by Sonoclot signature analysis are limited. Our purpose was to appraise coagulopathy using a dynamic test..

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Early mobilisation algorithm for the critical patient. Expert recommendations

Abstract Introduction  (ICU)-acquired weakness is developed by 40%–46% of patients admitted to ICU. Different studies have shown that Early Mobilisation (EM) is safe, feasible, cost-effective and improves patient outcomes in..

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Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Single-Blind,…

Abstract Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the rescue treatment proposed to patients with refractory cardiogenic shock. The VA-ECMO implantation promotes inflammation and ischemia-reperfusion injuries through the VA-ECMO flow, causing..

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Flow Monitoring of ECMO circuit for detecting Oxygenator Obstructions

Abstract Oxygenator thrombosis during extracorporeal membrane oxygenation (ECMO), is a complication that necessitates component replacement. ECMO centers monitor clot burden by intermittent measurement of pressure drop across the oxygenator. An..

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Adenosine Triphosphate - Sensitive Potassium Channel Opener Diazoxide Reduces Myocardial Stunning in a Porcine Lad Occlusion Model

Abstract Introduction: Adenosine triphosphate - sensitive potassium (KATP) channels provide endogenous myocardial protection by coupling cell membrane potential to metabolism, as they are inhibited by ATP and open during times of..

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Aortic Valve Replacement versus Conservative Treatment in Asymptomatic Severe Aortic Stenosis: The AVATAR Trial

Abstract Background: Surgical aortic valve replacement (SAVR) represents a class I indication in symptomatic patients with severe aortic stenosis (AS). However, indications for early SAVR in asymptomatic patients with severe AS..

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Flow displacement and decreased wall shear stress might be associated with the growth rate of an ascending aortic dilatation

Abstract     OBJECTIVES Our goal was to evaluate whether four-dimensional (4D) flow magnetic resonance imaging (MRI) can predict the growth rate of dilatation of the ascending aorta (AA) in..

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Reinterventions and new aortic events after aortic surgery in Marfan syndrome

Abstract     OBJECTIVES Pre-emptive strategies to manage the aortic complications of Marfan syndrome have resulted in improved life expectancy yet, secondary to the variation of phenotypic expression, anticipating the..

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Postcardiotomy Extracorporeal Membrane Oxygenation: Narrative Review Navigating the Ethical Issues

Abstract Postcardiotomy shock (PCS) is an uncommon and life-threatening .  (ECMO) is the first line of mechanical  for treating PCS when medical therapies are insufficient. Reaching a “therapeutic ceiling” or a “bridge to..

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Effect of body mass index on the clinical outcomes of adult patients treated with venoarterial ECMO for cardiogenic shock

Abstract Objective Current guidelines consider obesity to be a relative contraindication to veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock. The authors investigated the effect of body mass index..

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Factors for Acute Kidney Injury Following Total Arch Replacement and Association with Temperature Management During Cardiopulmonary Bypass: A Single-center Retrospective…

Abstract Many patients develop acute kidney injury (AKI) after vascular surgery. In this retrospective observational study, we investigated the risk factors for AKI defined using the Kidney Disease Improving Global..

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An ex vivo comparison of partial thromboplastin time and activated clotting time for heparin anticoagulation in an ovine model

Abstract Background Sheep are a primary model of mechanical circulatory support (MCS) with heparin anticoagulation therapy frequently being monitored by activated clotting time (ACT) due to ease and cost. In..

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Pregnant/Peripartum Women with COVID-19 High Survival with ECMO: An ELSO Registry Analysis

Abstract In the US, 131,512 pregnant/peripartum women have been affected by Coronavirus Disease 2019 (COVID-19), with 200 associated deaths (0.15%) [1]. The hormonal, physiological, and immunomodulatory changes during pregnancy increase..

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Prediction Scores for Any-Stage and Stage-3 Acute Kidney Injury After Adult Cardiac Surgery in a Chinese Population

Abstract Objectives This study was performed to internally derive and then validate risk score systems using preoperative and intraoperative variables to predict the occurrence of any-stage (stage 1, 2, 3)..

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A Retrospective Study of Infection in Patients Requiring Extracorporeal Membrane Oxygenation Support

Abstract Background Healthcare-associated infections (HAIs) in critically ill patients are a serious public health problem. Extracorporeal membrane oxygenation (ECMO) has been used increasingly for patients with severe cardiac or respiratory..

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Neurocognitive decline in cardiac surgery—Distraction rather than destruction?

Abstract Background A neurocognitive decline is an undesirable event that can be observed in patients after cardiac surgery. It has been related to the use of cardiopulmonary bypass (CPB). Minor..

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Percutaneous cannulation for cardiopulmonary bypass in robotic mitral valve surgery with zero groin complications

Abstract Introduction Robotic valve surgery utilizes the femoral vessels to set up cardiopulmonary bypass (CPB) which translates to groin wound and lower extremity vascular complications. A less invasive technique is..

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Pharmacokinetics of Antibiotics in Pediatric Intensive Care: Fostering Variability to Attain Precision Medicine

Abstract Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors...

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Ex Vivo Allograft Perfusion for Complex Pediatric Heart Transplant Recipients

Abstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..

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Effect of Perioperative Lipid Status on Clinical Outcomes after Cardiac Surgery

Abstract Patients undergoing cardiac surgery are at increased cardiovascular risk, which includes altered lipid status. However, data on the effect of cardiac surgery and cardiopulmonary bypass (CPB) on plasma levels..

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Comparison of del Nido Cardioplegia vs blood cardioplegia in adult aortic surgery is the single-dose cardioplegia technique really advantageous?

Abstract Background Objective: The aim of the present study was to compare the operative and early postoperative results of the use of del Nido  solution (dNCS) with traditional blood cardioplegia..

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