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Preventing Stroke in Aortic Arch Operations

Abstract Progress in aortic arch surgery has paralleled advances in cerebral protection. Since DeBakey’s first successful arch repair, neurologic complications have remained a major determinant of outcomes. The evolution of..

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Long-term quality of life and functional outcomes in extracorporeal membrane oxygenation survivors

Abstract Extracorporeal membrane oxygenation (ECMO) has become an increasingly vital intervention for patients with severe cardiac and respiratory failure, significantly improving short-term survival rates. However, there is growing recognition of..

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ELSO-score: A practical pre-ECMO risk model for predicting in-hospital mortality in patients receiving VA-ECMO

Abstract Background Despite advancements in management strategies, patients with refractory cardiogenic shock (CS) have high mortality. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly utilized as temporary mechanical support in these..

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Artificial Intelligence in Adult Cardiovascular Medicine and Surgery: Real-World Deployments and Outcomes

Abstract Artificial intelligence (AI) is rapidly reshaping adult cardiac surgery, enabling more accurate diagnostics, personalized risk assessment, advanced surgical planning, and proactive postoperative care. Preoperatively, deep-learning interpretation of ECGs, automated..

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Hemofilters versus hemodialyzers: impacts on cytokine removal during cardiopulmonary bypass in pediatric cardiac surgery: a randomized controlled trial

Abstract Background Congenital heart disease (CHD) remains a leading cause of pediatric morbidity and mortality worldwide. Cardiopulmonary bypass (CPB) is crucial for surgical repair but is associated with systemic inflammation..

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Prophylactic temporary mechanical circulatory support: The new paradigm in cardiac surgery

Abstract Background Post-cardiotomy cardiogenic shock (PCCS) remains one of the most lethal complications of cardiac surgery, with high in-hospital mortality despite major improvements in operative techniques, and intensive care management...

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A Novel Trans-Septal Cannula for Wearable Extracorporeal Membrane Oxygenation: In Vitro Hemodynamic Evaluation and Placement Feasibility

Abstract Extracorporeal membrane oxygenation (ECMO) supports patients with end-stage heart and lung disease awaiting transplantation. In pulmonary hypertension, veno-arterial ECMO (VA-ECMO) is common but linked to vascular complications and limited..

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Factors associated with device-associated health care-associated infections after cardiac surgery: a matched cohort study

Abstract Background The study aimed to identify the patient-related and procedure-related factors independently associated with the development of device-associated health care-associated infections (DA-HAIs) in cardiac intensive care unit (CICU), specifically..

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Hemodynamic monitoring during veno-venous extracorporeal membrane oxygenation: A scoping review

Abstract Background In adult patients receiving veno-venous Extracorporeal Membrane Oxygenation (VV ECMO), cardiovascular performance plays a critical role in determining oxygen delivery, organ perfusion and safe titration of extracorporeal support...

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Intraoperative respiratory exchange ratio to predict complications after cardiopulmonary bypass surgery: a retrospective cohort study

Abstract The respiratory exchange ratio (RER), defined as the ratio of carbon dioxide (CO2) production to oxygen (O2) consumption, may be a non-invasive and continuously measurable alternative to lactate for..

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Modified Extracorporeal Circulation (mECC) for enhanced blood conservation in thoracoabdominal aortic surgery: A single-center experience

Abstract Background Thoracoabdominal aortic aneurysm (TAAA) repair is associated with significant risks of blood loss and organ ischemia. This study evaluates the efficacy of a novel, modified Extracorporeal Circulation (mECC)..

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ECMO transports perspectives on organization and patient management: A narrative review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is an established life support technique for refractory acute cardiorespiratory failure in children and adult patients. However, ECMO support is provided only by specialized..

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Use of extracorporeal circulation in multidisciplinary approach and replantation strategies for traumatic limb amputations: A case report

Abstract Background Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal..

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Predictors and clinical outcomes associated with prolonged mechanical ventilation following major cardiac surgery

Abstract Background Prolonged mechanical ventilation (PMV) after major cardiac surgery is associated with increased morbidity, mortality, and healthcare utilization. Objectives To determine independent perioperative predictors of PMV and assess its..

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Goal-directed perfusion during cardiopulmonary bypass: Physiological rationale, clinical evidence, and critical appraisal

Abstract Objectives Cardiopulmonary bypass (CPB) is essential to cardiac surgery but is associated with organ injury from non-physiological perfusion. Goal-directed perfusion (GDP) has emerged as a physiology-based strategy to optimize..

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Extracorporeal life support in lung transplantation with dual-lumen cannulas: A systematic review

Abstract Background Refractory end-stage lung failure may benefit from extracorporeal life support (ECLS) as a bridge to lung transplantation. Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is indicated in patients who..

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Association Between Core Body Temperature at the Time of Separation From Cardiopulmonary Bypass and Postoperative Acute Kidney Injury: A Retrospective…

Abstract Objectives Although hyperthermic perfusion (arterial outlet temperature >37°C) during cardiopulmonary bypass (CPB) is associated with acute kidney injury (AKI), the impact of body temperature at the time of separation..

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Changes in hemodynamics, cardiac energetics, and cell signaling pathways induced by veno-arterial extracorporeal membrane oxygenation with or without left ventricular…

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..

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Impact of eosinophil levels on postoperative clinical outcomes in patients undergoing extracorporeal circulation: a retrospective cohort study

Abstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..

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Development of a Plasma Free Hemoglobin-Adsorbing Device for Extracorporeal Therapies

Abstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..

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ELSO guidelines development: A roadmap

Abstract The Extracorporeal Life Support Organization (ELSO) has progressively transformed its guideline framework to meet the increasing clinical, scientific, and operational demands of modern extracorporeal life support. Since its establishment..

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Takotsubo Cardiomyopathy After Cardiac Surgery: A Hidden Menace

Abstract Background Takotsubo cardiomyopathy (TTC) is an episode of transient left ventricular (LV) dysfunction affecting 2.1% of patients with suspected acute ST-segment elevation myocardial infarction. Case Summary A 61-year-old woman..

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Development of new antithrombotic drugs for children (part 1): guidance from the ISTH SSC Subcommittee on Pediatric and Neonatal Thrombosis…

Abstract As adult programs of newer anthrombotic agents, such as those directed against FXIa, are underway, there is both a pressing need and a great opportunity to optimize the design,..

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Preoperative Platelet Count Predicts In-Hospital Mortality in Patients Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Cohort Study

Abstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...

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Development and external validation of a machine learning model for predicting severe immediate postoperative complications in adults undergoing cardiac surgery

Abstract Background Patients undergoing cardiac surgery are at high risk of severe immediate postoperative complications. Predicting immediate postoperative adverse events remains challenging owing to the complex and nonlinear interplay of..

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Systemic and Pulmonary Microcirculation, Double Microcirculation: From Basic Concepts to Treatment Key Points

Abstract It seems logical to divide the macrocirculation into systemic and pulmonary circulation, but it is rare in clinical practice to further subdivide microcirculation into systemic and pulmonary microcirculation. Both..

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Beating Heart Removal of an Aortic Arch Thrombus Under Total Body Perfusion

Abstract Floating thrombi of the aortic arch constitute rare yet highly consequential lesions with high embolic risk for which optimal management remains debated. Conventional surgical management typically requires deep hypothermic..

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Minimally invasive extracorporeal CO2 removal in hypercapnic respiratory failure: a prospective observational study

Abstract Background Lung-protective ventilation in acute respiratory distress syndrome (ARDS) can lead to hypercapnia, an independent risk factor for increased mortality. Extracorporeal CO2 removal (ECCO2R) enables further reduction of ventilator intensity,..

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Impact of combined ECMO - CRRT support on patient outcomes and risk factors: a multicenter retrospective study

Abstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..

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Modified Del Nido “microplegia” reduces intraoperative, postoperative, and total blood products

Abstract Objectives Previous studies have shown that Buckberg microplegia reduces the need for intraoperative blood transfusion by minimizing hemodilution. However, this approach has been largely understudied in the context of..

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