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Autotransfusion in traumatic haemothorax using the Sinapi chest drain system

Abstract A previously well 23-year-old man presented to the Trauma Department of a large urban Level 1 Trauma Centre in South Africa. The patient sustained a stab wound to the..

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Healthcare professionals’ views on training, standards, and resources for extracorporeal membrane oxygenation: a cross-sectional survey

Abstract Aim To assess health care professionals’ knowledge and opinions regarding extracorporeal membrane oxygenation (ECMO) use, training, standards, and resource availability. Methods This cross-sectional study employed an online self-administered survey..

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Impact of Advanced Cardiac Life Support Medications on Discharge Neurological Function for Survivors of Cardiac Arrest When Using ECPR

Abstract BACKGROUND: While the immediate goal of cardiopulmonary resuscitation is to achieve return of spontaneous circulation, the patient-centered goal is to minimize neurological injury. Several medications used during cardiac arrest..

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Blood Conservation Protocol for Patients Undergoing Left Ventricular Assisted Device Implantation

Abstract Objectives:  This study aims to compare intraoperative blood transfusion and perioperative outcomes for patients undergoing left ventricular assist device (LVAD) implantation before and after the implementation of a blood..

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ABO-incompatible heart transplants in children aged 2-9 years: A new paradigm in transplant?

Abstract Background and Aims Pediatric heart transplantation remains hampered by the limited availability of donor organs. The introduction of ABO-incompatible (ABOi) heart transplantation for infants in the early 2000s expanded..

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Incidence and Risk Factors of Limb Ischaemia in Adult Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis

Abstract Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become an essential life-saving therapy for patients with refractory cardiogenic shock, cardiac arrest, and severe cardiopulmonary failure. Despite its expanding use and..

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Combined Inhaled Pulmonary Vasodilators in Cardiac Surgery: A Scoping Review

Abstract Pulmonary hypertension is a risk factor for increased morbidity and mortality in cardiac surgery. The use of a combination of inhaled vasodilator agents could have an improved effect on..

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Clinical Evaluation of the Hemostatic Efficacy and Safety of a Biodegradable Hemostatic Agent, Hemogram: A Comparative Study with Arista™ AH

Abstract Background Hemogram is a novel biodegradable powdered hemostatic agent developed by binding calcium ions (Ca²+) to carboxymethyl starch (CM-starch) and applying granulation technology to enhance blood absorption and hemostatic..

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Towards an understanding of best practice: The good, the bad and the future of cardiogenic shock teams

Abstract Cardiogenic shock (CS) remains a high-mortality condition that demands rapid diagnosis, coordinated multidisciplinary management, and timely initiation of mechanical circulatory support. As more institutions implement dedicated CS teams, substantial..

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Risk factors for a central-to-peripheral arterial blood pressure gradient in adults: a systematic review

Abstract Purpose Accurate hemodynamic monitoring is essential for personalized care in surgical and intensive care unit (ICU) settings, and radial artery catheters are the gold standard. Nevertheless, central-to-peripheral arterial blood..

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The comparison of circuit lifespan between integration and separation approach in extracorporeal membrane oxygenation patients requiring continuous renal replacement therapy…

Abstract Background: The estimated incidence of acute kidney injury requiring renal replacement therapy (RRT), mainly continuous RRT (CRRT), in patients necessitating extracorporeal membrane oxygenation (ECMO) is approximately 50%. Currently, two..

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First Application of an Eddy-Scale Hemolysis Model to the Food and Drug Administration Nozzle Using Computational Fluid Dynamics

Abstract Computational fluid dynamics (CFD) is increasingly important in biomedical engineering; however, its use in medical device design remains constrained by regulatory requirements for model validation and verification. To address..

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Refractory septic shock: our updatedpragmatic approach

Abstract Despite the refinement in guidelines and improving outcomes, a subset of patients with septic shock fails to respond to treatment and progresses into refractory septic shock with an associated..

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Impaired endotoxin inactivation, rather than gut translocation, is associated with organ injury in cardiac surgery with cardiopulmonary bypass

Abstract BACKGROUNDS  In patients with cardiac surgery under cardiopulmonary bypass (CPB), postoperative inflammation is a driver of adverse outcomes. Endotoxaemia is one of the factors thought to trigger this inflammatory..

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Lucian Leape’s legacy for patient safety

Abstract In losing Lucian Leape to heart failure last 30 June, at the age of 94 years, we lost a rare physician whose insights fundamentally changed how clinicians and the..

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Hydrogen Gas via Extracorporeal Membrane Oxygenation and Its Effects on Oxidative Stress, Coagulation, and Inflammation: An Ex Vivo Model

Abstract Hydrogen has emerged as a therapeutic agent in inflammatory critical illnesses due to its potential to modulate inflammation and oxidative stress. However, its role in extracorporeal membrane oxygenation (ECMO),..

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Peripheral Nerve Injuries in Patients Undergoing Congenital Cardiac Surgery and Cardiac Catheterization

Abstract Objectives Peripheral nerve injury (PNI) is a clinically significant but frequently under-recognized complication after cardiac surgery and catheterization, contributing to postoperative morbidity. While PNI has been well characterized in..

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Breaking the Rhythm: Extracorporeal Membrane Oxygenation (ECMO) as a Life Saver in a Case of Resistant Arrhythmia and Cardiac Arrest

Abstract Refractory ventricular arrhythmias and cardiac arrest in younger patients are rare, life-threatening events, particularly when standard resuscitation fails. Extracorporeal membrane oxygenation (ECMO) provides temporary circulatory support, enabling hemodynamic stabilization,..

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Viscoelastic Testing to Guide Anticoagulation During Extracorporeal Membrane Oxygenation in Lung Transplantation

Abstract Extracorporeal membrane oxygenation (ECMO) represents an established modality of intraoperative circulatory and respiratory support during lung transplantation (LTx). Systemic anticoagulation with unfractionated heparin (UFH) remains essential to prevent circuit..

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Development and validation of a machine learning-based prediction model for thrombocytopenia following cardiopulmonary bypass

Abstract Postoperative thrombocytopenia (TP) is a serious complication of cardiopulmonary bypass (CPB). An accurate prediction model is crucial for the early identification of high-risk patients. This study aimed to develop..

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Outcomes in Patients Requiring VENO-Venous Extracorporeal Membrane Oxygenation After Cardiac Surgery: An Analysis From the PELS-1 Study

Abstract Background Acute respiratory failure after cardiac surgery is an uncommon complication, affecting morbidity and mortality. In these patients, respiratory extracorporeal membrane oxygenation (ECMO) support may be beneficial, as it..

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Hemoglobin Optimization and Transfusion Reduction Through Anemia and Iron Deficiency Correction: A Post Hoc Prospective Study in Cardiac Surgery

Abstract Objectives To assess whether systematic perioperative correction of anemia and/or iron deficiency (ID) improves hemoglobin (Hb) levels and reduces transfusion requirements in elective cardiac surgery. Design Post hoc analysis..

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Implementation of emergency extracorporeal membrane oxygenation in a hospital without on-site cardiothoracic surgery support

Abstract Introduction Extracorporeal cardiopulmonary resuscitation (ECPR) using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a treatment option for refractory cardiac arrest patients, but it has mostly been restricted to hospitals with..

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Extracorporeal Membrane Oxygenation Related Axillary Artery Cannulation and Aortic Hemodynamics: Insights From Computational Fluid Dynamics

Abstract Axillary and subclavian artery cannulation for veno-arterial extracorporeal membrane oxygenation (V-A ECMO) offers clinical advantages but introduces complex flow dynamics within the aortic arch. This study employed patient-specific computational..

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Damage-Associated Molecular Patterns in Perioperative Anesthesia Care: A Clinical Perspective

Abstract Damage-associated molecular patterns (DAMPs) are endogenous molecules released during cellular stress or injury that trigger sterile inflammation. In perioperative settings, common triggers include surgical trauma, ischemia–reperfusion injury, cardiopulmonary bypass,..

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Custodial-HTK Cardioplegia in Conventional Cardiac Surgery: A Retrospective Analysis From UiTM

Abstract Myocardial protection remains one of the most critical determinants of success in cardiac surgery, particularly during prolonged ischemic periods associated with cardiopulmonary bypass and aortic cross-clamping. The article Custodial-HTK..

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Extracorporeal Membrane Oxygenation Discontinuation Due to Resource Limitations

Abstract To examine the global epidemiology of extracorporeal membrane oxygenation discontinuation due to resource limitation (EDRL), assessing differences across geographic regions and between pre- and post-coronavirus disease 2019 (COVID-19) periods...

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Challenges of ECMO use for severe trauma: a narrative review

Abstract Background Patients with severe trauma are at high risk of developing life-threatening complications, including acute respiratory failure and circulatory collapse. Extracorporeal membrane oxygenation (ECMO) offers critical support when conventional..

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Ultrasound in Extracorporeal Membrane Oxygenation: An ELSO State-of-the-Art Review

Abstract Ultrasound has become indispensable in the management of patients supported with extracorporeal membrane oxygenation (ECMO), enabling rapid diagnosis, procedural guidance, physiologic monitoring, and informed decision-making across the entire ECMO..

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Predictive Power of the Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion Score for Cardiac Surgery–Associated Acute Kidney Injury:…

Abstract Objectives The Association of Cardiothoracic Anesthetists Perioperative Risk of Blood Transfusion (ACTA-PORT) score was originally developed to predict the need for transfusion in cardiac surgery patients. Given the inter-relationship..

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