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Outcomes after neonatal cardiac surgery: The impact of a dedicated neonatal cardiac program

Abstract Objectives Prematurity is a risk factor for in-hospital mortality after cardiac surgery. The structure of  models designed to deliver optimal care to neonates including those born preterm with critical  is unknown...

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The use of artificial intelligence for automating or semi-automating biomedical literature analyses: A scoping review

Abstract Objective Evidence-based medicine (EBM) is a decision-making process based on the conscious and judicious use of the best available scientific evidence. However, the exponential increase in the amount of..

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A nomogram to predict postoperative pulmonary complications after cardiothoracic surgery

Abstract Objective The objective was to develop a novel scoring system that would be predictive of postoperative pulmonary complications in critically ill  after cardiac and major . Methods A total of 17,433..

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Lung ultrasound in acute and chronic heart failure. A Clinical Consensus Statement of the European Association of Cardiovascular Imaging (EACVI)

Lung ultrasound in acute and chronic heart failure. A Clinical Consensus Statement of the European Association of Cardiovascular Imaging (EACVI)

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Effect of flow rate ratio and positioning on a lighthouse tip ECMO return cannula

Abstract Extracorporeal membrane oxygenation is a life-saving support therapy in the case of cardiopulmonary refractory failure. Its use is associated to complications due to the presence of artificial surfaces and..

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Nonischemic Donor Heart Preservation: New Milestone in Heart Transplantation History

Abstract Heart transplantation is considered the gold standard for the treatment of advanced end-stage heart failure. However, standard donors after brain death are decreasing, whereas patients on the heart transplant waitlist are..

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Technical considerations for percutaneous pulmonary artery cannulation for mechanical circulatory support

Abstract Objectives Percutaneous pulmonary artery cannulas, used as inflow for left ventricular venting or as outflow for right ventricular mechanical circulatory support, are easily and rapidly deployable with transesophageal and..

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Exogenous nitric oxide delivery protects against cardiopulmonary bypass–associated acute kidney injury: Histologic and serologic evidence from an ovine model

Abstract Objective Several human studies have associated nitric oxide administration via the cardiopulmonary bypass circuit with decreased incidence of cardiopulmonary bypass–associated acute kidney injury, but histopathologic and serologic evidence of..

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Veno-Arterial Extracorporeal Membrane Oxygenation for Amniotic Fluid Embolism: A Report From the Extracorporeal Life Support Organization Registry

Abstract Amniotic fluid embolism (AFE) is a potentially lethal complication of pregnancy that results from disruption of the maternal–fetal interface and occurs as frequently as one in every 8,000 deliveries. When AFE..

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Percutaneous decannulation of venoarterial extracorporeal membrane oxygenation using the Manta vascular closure device: A systematic review and meta-analysis

Abstract Objectives To perform a systematic review and meta-analysis of the techniques and outcomes associated with percutaneous decannulation of venoarterial extracorporeal membrane oxygenation (VA–ECMO) using the Manta vascular closure device...

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Detecting the Change in Total Circulatory Flow with a Wireless, Wearable Doppler Ultrasound Patch: A Pilot Study

Abstract OBJECTIVE:  Measuring fluid responsiveness is important in the management of critically ill patients, with a 10–15% change in cardiac output typically being used to indicate “fluid responsiveness.” Ideally, these changes would..

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Hereditary angioedema in cardiac surgery: Perioperative management considerations for a rare disease

Abstract Introduction Hereditary Angioedema is a rare disease caused by C1 esterase inhibitor deficiency leading to diffuse and potentially life-threatening oedema formation. Preventing attacks is critical, particularly for patients undergoing..

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Continuous Contactless Measurement of Blood Volume Inside Venous Reservoirs for Cardiopulmonary Bypass

Abstract During a cardiopulmonary bypass (CPB) procedure using a heart-lung machine, the volume of blood inside the venous reservoir is a crucial piece of information for the perfusionist to make..

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Poorly controlled hypertension is associated with increased coronary myogenic tone in patients undergoing cardiac surgery with cardiopulmonary bypass

Abstract Objective  and  dysregulate coronary  tone, which can be further affected by common   undergoing cardiac surgery. This study investigates differences in coronary myogenic tone and  to  before and after cardioplegia and  based on hypertension history. Methods..

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Hydromorphone mitigates cardiopulmonary bypass-induced acute lung injury by repressing pyroptosis of alveolar macrophages

Abstract Introduction  Acute lung injury (ALI) is a devastating pulmonary illness with diffuse inflammatory responses. Hydromorphone (Hyd) is an opioid agonist used for relieving moderate-to-severe pain. The present work investigated the..

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Prolonged cardiovascular pharmacological support and fluid management after cardiac surgery

Abstract Objective To identify potentially modifiable risk factors related to prolonged cardiovascular pharmacological support after weaning from cardiopulmonary bypass (CPB). Methods This is a secondary analysis of two prospective cohort..

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Point-of-Care Viscoelastic Hemostatic Assays in Cardiac Surgery Patients: Comparison of Thromboelastography 6S, Thromboelastometry Sigma, and Quantra

Abstract Objectives Viscoelastic tests allow a reduction in blood product transfusion. Three modern devices are currently available (rotational  [ROTEM] sigma,  [TEG] 6S, and Quantra). No study has compared the performances of these..

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Combined Extracorporeal Lung and Kidney Support in Fluid Overload

Abstract During artificial organ support, kidney injury is multifactorial and related to the high severity of patients treated with extracorporeal membrane oxygenation (ECMO). The successful delivery of continuous renal replacement..

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Modified Ultrafiltration Should Not Be Routinely Used in Adult Cardiac Surgery

Abstract Pediatric Literature As the practice of ultrafiltration arose from pediatric cardiac surgery, much of the evidence to support MUF is from low-powered pediatric studies. Some early, single-center literature, as..

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Modified Ultrafiltration Is Beneficial for Adults Undergoing Cardiac Surgery

Abstract Hemodilution and Volume Overload The use of CPB necessitates priming of the CPB circuit, which is typically accomplished using 1-to-2 liters of a crystalloid solution. In addition, 1-to-3 liters..

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Cost-Effectiveness of Cell Salvage in Trauma Blood Transfusions

Abstract Introduction Despite the increasing amount of evidence supporting its use, cell salvage (CS) remains an underutilized resource in operative trauma care in many hospitals. We aim to evaluate the..

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Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries: a public health…

Abstract The global burden of paediatric and congenital heart disease (PCHD) is substantial. We propose a novel public health framework with recommendations for developing effective and safe PCHD services in low-income..

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Sounding the Alarm: What Clinicians Need to Know about Physical, Emotional and Cognitive Recovery After Venoarterial Extracorporeal Membrane Oxygenation

Abstract Objective:  We summarize the existing data on the occurrence of physical, emotional, and cognitive dysfunction associated with postintensive care syndrome (PICS) in adult survivors of venoarterial extracorporeal membrane oxygenation..

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The Use of Cardioprotective Devices and Strategies in Patients Undergoing Percutaneous Procedures and Cardiac Surgery

Abstract In the United States, about one million people are seen to visit the operating theater for cardiac surgery annually. However, nearly half of these visits result in complications such..

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How do we forecast tomorrows’ transfusion: Non-transfusional hemotherapy

Abstract Hemotherapy is the treatment of diseases by the use of blood or blood products from blood donation (by others of for oneself). It is clear that blood components transfusion..

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Supplemental fibrinogen restores thrombus formation in cardiopulmonary bypass-induced platelet dysfunction ex vivo

Abstract Background Major cardiac surgery related blood loss is associated with increased postoperative morbidity and mortality. Platelet dysfunction is believed to contribute to post-cardiopulmonary bypass (CPB)-induced microvascular bleeding. We hypothesised..

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Gene Expression of Inflammatory Cytokines in Major Organs by Extracorporeal Circulation

Abstract Background: Extracorporeal circulation (ECC) is indispensable for cardiac surgery. Despite the fact that ECC causes non-physiological damage to blood components, its pathophysiology has not been fully elucidated. In our..

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Application of 1,000 fps High-Speed Angiography to In-Vitro Hemodynamic Evaluation of Left Ventricular Assist Device Outflow Graft Configurations

Abstract Left ventricular assist device (LVAD)–induced hemodynamics are characterized by fast-moving flow with large variations in velocity, making quantitative assessments difficult with existing imaging methods. This study demonstrates the ability of..

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Contemporary practice and perception of autologous blood salvage in hepato-pancreatico-biliary operations: an international survey

Abstract Background This study aimed to assess contemporary knowledge, attitudes and behaviors around transfusion of intraoperative salvaged blood (sRBCt) during hepato-pancreatico-biliary (HPB) operations. Findings are meant to inform the design..

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