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The burden of peri-operative work at night as perceived by anaesthesiologists

Abstract BACKGROUND  No international data are available on the night working conditions and workload of anaesthesiologists and their opinions about associated risks. OBJECTIVE  The aim of this international survey was..

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Patient Blood Management in Pregnancy

Abstract Background: Patient blood management (PBM) is a multidisciplinary and patient-centered treatment approach, comprising the detection and treatment of anemia, the minimization of blood loss, and the rational use of allogeneic..

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Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Abstract BACKGROUND: Right ventricular failure (RVF) is a leading driver of morbidity and mortality after major cardiac surgery for advanced heart failure, including orthotopic heart transplantation and left ventricular assist..

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Risk factors for postoperative myocardial injury-related cardiogenic shock in patients undergoing cardiac surgery

Abstract Background Myocardial injury-related cardiogenic shock (MICS) is significantly associated with poor outcomes in patients after cardiac surgery. Herein, we aimed to investigate the risk factor for postoperative MICS. Methods..

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The association between intraoperative cardiopulmonary bypass power and complications after cardiac surgery

Abstract Background Low cardiac power (product of flow and pressure) has been shown to be associated with mortality in patients with cardiogenic shock after acute myocardial infarction, but has not..

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The heart-lung machine in major limb replantation: Report of two cases

Abstract Replantation of amputated limbs after long ischemic hours almost always comes with reperfusion syndrome and poor outcomes. An ischemic time of greater than 6 h is often considered unsuitable for..

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Expression and Significance of KIM-1, NGAL, and HO-1 in Patients with Acute Kidney Injury After Cardiac Valve Replacement

Abstract Objective: To investigate the changes and significance of perioperative expression levels of kidney injury molecule-1 (KIM-1), neutrophil gelatinase-related lipocalin (NGAL), and heme oxygenase-1 (HO-1) in patients with acute kidney injury..

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Standardized approach for extubation during extracorporeal membrane oxygenation in severe acute respiratory distress syndrome: a prospective observational study

Abstract Background Extubation during extracorporeal oxygenation (ECMO) in severe acute respiratory distress syndrome(ARDS) has not been well studied. Despite the potential benefits of this strategy, weaning from ECMO before libera‑tion..

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Groundbreaking NIH Study Reveals: ECMO More Effective for Obese Patients than Previously Thought!

Abstract The escalating concern of obesity in the United States isn’t merely a statistic; it’s a palpable crisis. As of 2017-2018, the CDC noted that . The ramifications of this startling..

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Dynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO

Dynamic longitudinal increase in D-dimers: an early predictor of bleeding complications in ECMO

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Pathophysiology of COVID-19 pneumonia and respiratory treatment

Abstract COVID-19 pandemic has seen an unprecedented number of patients presenting with acute respiratory distress syndrome to the intensive care units all over the world. Between August and November 2022,..

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Use of Technology to Improve the Adherence to Surgical Safety Checklists in the Operating Room

Abstract Background Although checklists can improve safety in the operating room (OR), compliance with their use is variable. Use of a forcing function, a principle of human factors engineering, has..

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Effect of cardiopulmonary bypass on plasma and erythrocytes oxylipins

Abstract Background Oxylipins, the oxidative metabolites of polyunsaturated fatty acids (PUFAs), serve as key mediators of oxidative stress, inflammatory responses, and vasoactive reactions in vivo. Our previous work has established..

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Extracorporeal Blood Purification with CytoSorb in 359 Critically Ill Patients

Abstract Introduction: Critically ill patients with inflammatory dysregulation and organ disfunction may benefit from blood purification, although the use of this technique has not been described in large case series. We..

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Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials

Abstract Background Venoarterial  (VA-ECMO) is increasingly used  with  despite the lack of evidence from adequately powered . Three trials reported so far were underpowered to detect a survival benefit; we therefore conducted an individual..

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Intraaortic Balloon Pump Counterpulsation, Part I: History, Technical Aspects, Physiologic Effects, Contraindications, Medical Applications/Outcomes

Abstract Intraaortic balloon pump counterpulsation is the most common form of mechanical circulatory support used in patients with myocardial ischemia and cardiogenic shock. The physiologic principles of counterpulsation include diastolic..

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CytoSorb with Ex Vivo Organ Perfusion: Transforming the Future of Solid Organ Transplantation

Abstract PRINCETON, N.J., Sept. 11, 2023 (GLOBE NEWSWIRE) --   (NASDAQ: CTSO), a leader in the treatment of life-threatening conditions in intensive care and cardiac surgery using blood purification via its..

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Antithrombin III supplementation during neonatal and pediatric extracorporeal membrane oxygenation

Abstract Background Bleeding and thrombosis are common extracorporeal membrane oxygenation (ECMO) complications associated with increased mortality. Heparin is the most commonly used ECMO anticoagulant, employed in 94% of cases. Reduced..

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Mortality in Patients with Obesity and ARDS Receiving ECMO: The Multicenter ECMObesity Study

Abstract Rationale: Patients with obesity are at increased risk for developing acute respiratory distress syndrome (ARDS). Some centers consider obesity a relative contraindication to receiving extracorporeal membrane oxygenation (ECMO) support,..

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Routine ECMO in AMICS Patients Not Protective: ECLS-SHOCK

Abstract In patients with acute MI complicated by cardiogenic shock (AMICS) who are slated to undergo early revascularization, routine use of extracorporeal membrane oxygenation (ECMO) doesn’t reduce 30-day mortality. The..

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Detecting Oxygenator Thrombosis in ECMO: A Review of Current Techniques and an Exploration of Future Directions

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-support technique used to treat cardiac and pulmonary failure, including severe cases of COVID-19 (coronavirus disease 2019) involving acute respiratory distress syndrome. Blood..

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Children who suffer cardiac arrest more likely to survive at ECMO capable hospitals

Abstract Children who experience cardiac arrest are one and a half times more likely to survive at a hospital capable of providing the life support system called ECMO, research suggests...

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Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials

Abstract Background Venoarterial  (VA-ECMO) is increasingly used  with  despite the lack of evidence from adequately powered . Three trials reported so far were underpowered to detect a survival benefit; we therefore conducted an individual..

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Micellar Encapsulation of Propofol Reduces its Adsorption on Extracorporeal Membrane Oxygenator (ECMO) Circuit

Abstract Extracorporeal membrane oxygenation (ECMO) is a life-saving cardiopulmonary bypass device used on critically ill patients with refractory heart and lung failure. Patients supported with ECMO receive numerous drugs to..

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Association Between Postoperative Delirium and Long-Term Subjective Cognitive Decline in Older Patients Undergoing Cardiac Surgery: A Secondary Analysis of the…

Abstract Objectives This study aimed to evaluate whether a measure of subjective cognitive decline (SCD), the Patient-Reported Outcomes Measurement Information System (PROMIS) Applied Cognition-Abilities questionnaire, was associated with postoperative delirium...

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Heart transplant patients from socioeconomically distressed communities face higher mortality, organ failure risk

Abstract People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared..

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Outcomes of a modified, low-cost, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) for elective, periprocedural support of high-risk percutaneous cardiac interventions:…

Abstract Introduction High-risk procedures in interventional cardiology include a wide spectrum of clinical and anatomical scenarios related to a higher periprocedural morbidity and mortality. The prophylactic use of short-term mechanical..

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Pilot Testing of a Lightweight, Pulmonary Assist System in an Ambulatory Sheep Model of Destination Therapy Respiratory Support

Abstract A new, lightweight (2.3 kg), ambulatory pulmonary assist system (PAS) underwent preliminary evaluation in ambulatory sheep. The PAS was purposefully designed for long-term extracorporeal respiratory support for chronic lung..

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A Simple Formula for Predicting Ventricular Distension With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Left ventricular (LV) distention is a known complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO) due to increased afterload stress. The consequences of LV distension include elevated pulmonary venous pressures leading to pulmonary edema and increased wall..

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Accelerated Hemocompatibility Testing of Rotary Blood Pumps

Abstract Ex vivo hemocompatibility testing is a vital element of preclinical assessment for blood-contacting medical devices. Current approaches are resource intensive; thus, we investigated the feasibility of accelerating hemocompatibility testing by standardizing..

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