Archives

Perfusfind S.L.

Abstract Introduction Atrial fibrillation (AF) is the most common arrhythmia following cardiac surgery. Although many risk factors have been studied, none has emerged as a dominant and widely applicable prophylactic measure. Aim..

Perfusfind S.L.

Abstract Objective: Whole blood oxygen saturation and hemoglobin concentration are key markers of health across a variety of clinical contexts. Extracorporeal systems (dialysis, cardiopulmonary bypass, ECMO, etc.) require close monitoring..

Perfusfind S.L.

Abstract Background For patients presenting with cardiogenic shock due to acute myocardial ischaemia, veno-arterial extracorporeal membrane oxygenation (ECMO) is often the only potential lifesaving intervention remaining when revascularisation does not..

Perfusfind S.L.

Abstract Introduction Lysine analog antifibrinolytics (LAAF) like tranexamic acid (TXA) and aminocaproic acid (EACA) reduce intraoperative blood loss, especially in cardiac surgery where bleeding risks are high. These LAAFs inhibit..

Perfusfind S.L.

Abstract Time is critical in the diagnosis and treatment of cardiogenic shock, even more so than in septic shock. Early identification enables prompt circulatory support and restoration of tissue oxygenation. Baseline..

Perfusfind S.L.

Abstract Normothermic regional perfusion (NRP) has emerged as one of the most consequential innovations in modern liver transplantation, particularly in the context of controlled donation after circulatory death (cDCD). Historically,..

Perfusfind S.L.

Abstract Objective:  Postoperative pneumonia (POP) is a frequent complication after cardiac surgery, which significantly worsens prognosis. This study aimed to identify preoperative and intraoperative factors independently associated with POP in..

Perfusfind S.L.

Abstract Background Cardiac operations with cardiopulmonary bypass (CPB) trigger a systemic inflammatory response. To understand the underlying mechanisms behind the biological reactions during CPB, rat models that mimic clinical CPB..

Perfusfind S.L.

Abstract Introduction: Red blood cell (RBC) transfusions are frequent in cardiac surgery and are associated with higher morbidity, mortality, prolonged hospitalization, and increased healthcare costs. Several patient- and procedure-related factors have..

Perfusfind S.L.

Abstract Objectives To test the hypotheses that intraoperative hyperlactatemia is independently associated with increased postoperative infection risk in cardiac surgery with cardiopulmonary bypass (CPB). Methods This study involved 4970 cardiac..

Perfusfind S.L.

Abstract Wound healing after myocardial infarction (MI) is a dynamic and multifaceted process that links the molecular alterations induced by or in response to prolonged ischemia with structural and physiological..

Perfusfind S.L.

Abstract Background Audiovisual recording technology, referred to as the Operating Room Black Box (ORBB), is increasingly adopted in operating rooms (ORs) across several countries. It is described as beneficial, with..

Perfusfind S.L.

Abstract Since the use of heparin reversed by protamine is the gold standard for anticoagulation during cardiopulmonary bypass (CPB), a documented allergy to protamine represents a serious challenge for cardiac..

Perfusfind S.L.

Abstract Background: Andexanet alfa, a Gla-domainless mutant factor Xa (GDXa), reverses oral FXa inhibitors but can cause severe heparin resistance during cardiopulmonary bypass (CPB). Antithrombin (AT) supplementation may mitigate this..

Perfusfind S.L.

Abstract SEVERE HEMOPTYSIS REMAINS A significant medical emergency, often requiring a multidisciplinary approach to identify the bleeding source and implement effective treatment. Airway obstruction due to clots secondary to massive..

Perfusfind S.L.

Abstract Background Extracorporeal membrane oxygenation (ECMO) has emerged as a crucial modality in managing severe cardiac and respiratory failure; however, nosocomial infections and complex antimicrobial prescribing challenges may accompany its..

Perfusfind S.L.

Abstract Background Protamine is administered to reverse unfractionated heparin (UFH) after cardiopulmonary bypass (CPB), but dosing strategies—typically based on protamine-to-heparin (P:H) ratios—vary, and the minimal effective dose remains unclear. Reversal..

Perfusfind S.L.

Abstract Despite significant advancements in critical care practice and extracorporeal technology, refractory hypoxia remains a persistent clinical challenge during extracorporeal membrane oxygenation (ECMO). To demonstrate a systematic, algorithmic pathway for..

Perfusfind S.L.

Abstract Objectives To evaluate the efficacy of intraoperative hemoadsorption (HA) during cardiopulmonary bypass (CPB) in reducing acute kidney injury (AKI) and other major postoperative complications in patients undergoing cardiac surgery...

Perfusfind S.L.

Abstract Background After chemotherapy, a small subset of mediastinal non-seminomatous germ cell tumors evolves into growing benign teratoma masses despite normalized tumor markers. This condition is termed the growing teratoma..

Perfusfind S.L.

Abstract Objective(s) To evaluate survival outcomes and identify candidate profiles for venoarterial extracorporeal membrane oxygenation in adult patients with sepsis-induced cardiomyopathy. Design The authors systematically searched PubMed, Embase, and Google..

Perfusfind S.L.

Abstract Background Drawing on more than 30 years of valuable expertise in in-vitro, in-vivo, and clinical trials, we report the key findings of our institutional research on pulsatile cardiopulmonary bypass..

Perfusfind S.L.

Abstract Previously, limited cumulative experience has been linked to poor transplantation outcomes following ex vivo lung perfusion (EVLP). We sought to determine if EVLP performed at external perfusion centers (EPC) could mitigate..

Perfusfind S.L.

Abstract Background The COVID-19 pandemic has exacerbated the backlog of elective surgeries across the National Health Service (NHS). This is particularly critical for patients awaiting cardiac surgery, where even short delays..

Perfusfind S.L.

Abstract Background While the use of pre-hospital extracorporeal cardiopulmonary resuscitation for refractory out of hospital cardiac arrest is increasing, there is little data on whether it is cost-effective. This study..

Perfusfind S.L.

Abstract Background: Veno-arterial ExtraCorporeal Membrane Oxygenation (V-A ECMO) as a bridge to recovery or long-term assist devices in severe cardiocirculatory failure typically lasts 5-7 days. There is scarce guidance on..

Perfusfind S.L.

Abstract Purpose Cardiopulmonary bypass (CPB) is a well-established procedure that uses cannulae during cardiac surgery to drain and return blood. In challenging cases (e.g. aortic dissection, reoperation), peripheral cannulation in..

Perfusfind S.L.

Abstract Background Heparin is commonly administered to prevent thrombosis during cardiopulmonary bypass (CPB). However, the development of intracardiac thrombi under CPB has still been reported. Case summary A 79-year-old man..

Perfusfind S.L.

Abstract Fast-track extubation has emerged as a vital component of Enhanced Recovery After Surgery pathways, designed to optimize recovery and resource utilization after cardiac surgery, contrasting with traditional prolonged ventilation...

Perfusfind S.L.

Abstract Objective Cardiopulmonary bypass (CPB), which induces pulmonary injury, significantly impacts the quality of life in patients undergoing cardiac surgery. Preventing and treating pulmonary complications has become a critical clinical..