Archives

thumbnail
0 comment

Bleeding in Patients With Infarct-Related Cardiogenic Shock: A DanGer Shock Substudy

Abstract Background The microaxial flow pump (mAFP) has demonstrated improved outcomes in selected patients with ST-segment elevation acute myocardial infarction and cardiogenic shock (STEMI-CS). However, its use has been associated..

Read More
thumbnail
0 comment

Biomarkers of multi-organ dysfunction in ECMO: prognostic signposts for palliative transitions

Abstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..

Read More
thumbnail
0 comment

Correlation of anticoagulation assays with bleeding during extracorporeal membrane oxygenation at a tertiary pediatric hospital

Abstract Introduction Due to anticoagulation during Extracorporeal Membrane Oxygenation (ECMO), patients face a higher risk of bleeding. This study aimed to assess the correlation between anticoagulation assays and hemorrhage in..

Read More
thumbnail
0 comment

Nationwide outcomes of cardiac surgery in patients with cannabis use disorder

Abstract Objective To characterize in-hospital morbidity and mortality in patients undergoing cardiovascular surgery with and without cannabis use disorder (CUD) using a national database. Methods Between 2016 and 2018, 846,837..

Read More
thumbnail
0 comment

Impact of surgical non-technical skills on clinical outcomes: systematic review

Abstract Background Deficiencies in non-technical skills (NTS) such as leadership and communication can lead to intraoperative inefficiency and error. However, the relationship between these skills and patient-level outcomes has yet..

Read More
thumbnail
0 comment

Awake vs. Sedated Cannulation for Extra-Corporeal Membrane Oxygenation in Patients with COVID-19 Induced Acute Respiratory Distress Syndrome

Abstract Background: Veno-venous extra-corporeal membrane oxygenation (ECMO) cannulations are mostly performed while patients are heavily sedated and mechanically ventilated. For patients with acute respiratory distress syndrome (ARDS), cannulating for ECMO while..

Read More
thumbnail
0 comment

Development and Evaluation of a Multimodal Debriefing Dashboard for Virtual Reality Cardiac Arrest Simulation

Abstract Introduction  Wearable sensing technologies incorporated into virtual reality (VR) headsets can provide a number of unique, previously hidden insights into individual and team learning and performance in complex environments...

Read More
thumbnail
0 comment

Severe hyperammonemia following coronary artery bypass grafting

Abstract Background Hyperammonemia is a rare but serious cause of encephalopathy, commonly associated with hepatic dysfunction. However, non-hepatic hyperammonemia (NHHA) can arise due to impaired gastrointestinal transit, urease-producing organisms, and..

Read More
thumbnail
0 comment

Twenty-eight cases of thalassemia: A retrospective study of autologous and allogeneic erythrocyte transfusions during cesarean section

Abstract Aim Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested..

Read More
thumbnail
0 comment

Association of Vitamin C Administration with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Single-Center Retrospective Exploratory Cohort Study

Abstract Objectives: Oxidative stress after cardiac surgery may disrupt the blood–brain barrier and contribute to postoperative delirium (POD). Although associations between oxidative stress and POD are recognized, whether vitamin C (VC)..

Read More
thumbnail
0 comment

How I monitor lung function during mechanical ventilation and veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome

Abstract Purpose of review  Mechanical ventilation (MV) is central to the management of acute respiratory distress syndrome (ARDS). In refractory cases, veno-venous extracorporeal membrane oxygenation (VV-ECMO) can provide adequate gas..

Read More
thumbnail
0 comment

Delirium after cardiac surgery incidence and perioperative risk factors in a prospective cohort

Abstract Background Delirium is an aetiologically nonspecific cerebral syndrome characterised by disturbances in consciousness, attention, perception, cognition, memory, psychomotor activity, emotion, and the sleep–wake cycle. It frequently occurs after cardiac..

Read More
thumbnail
0 comment

Quantitative Evaluation of Hemolysis Under Excessive Static and Repeated Negative Pressure During Blood Handling

Abstract Background: Hemolysis, defined as the rupture of red blood cells (RBCs) with the release of hemoglobin into plasma, is a common concern during blood collection and extracorporeal circulation. Although..

Read More
thumbnail
0 comment

The Rate of Platelet Count Decline on Cardiopulmonary Bypass With a Sorin S5 Roller Pump

Abstract To the Editor: I wish to share the results of a retrospective observational correlation study I completed recently. While it is well established that the platelet count is negatively..

Read More
thumbnail
0 comment

Securing data management systems in perfusion: A narrative review on cybersecurity and clinical risk

Abstract Background The increasing digitization of perfusion practice has led to the integration of advanced data management systems (DMS) that record and analyze intraoperative variables in real time. While these..

Read More
thumbnail
0 comment

Unfractionated Heparin Dosing in Pediatric Venoarterial Extracorporeal Membrane Oxygenation: Single-Center Retrospective Study, 2015–2021

Abstract Objective:  Unfractionated heparin (UFH) is the most widely used anticoagulant during extracorporeal membrane oxygenation (ECMO). Optimal dosing of UFH for children undergoing ECMO is unknown, leading to suboptimal exposure...

Read More
thumbnail
0 comment

Characterization of PEG-Modified Composite Membranes for Microfluidic Oxygenator Applications

Abstract Microfluidic oxygenators promise to advance extracorporeal membrane oxygenation (ECMO) devices with enhanced hemodynamics and low prime volume. We are developing a silicon-based membrane oxygenator that will offer improved gas..

Read More
thumbnail
0 comment

Risk of Developing Lower Limb Ischemia in Patients With Extracorporeal Cardiopulmonary Resuscitation: A Secondary Analysis of the Study of Advanced…

Abstract Objectives:  While potential risks for limb ischemia have been explored in studies of venoarterial extracorporeal membrane oxygenation (ECMO), they remain inadequately defined for patients undergoing extracorporeal cardiopulmonary resuscitation (ECPR)...

Read More
thumbnail
0 comment

Automated Thromboelastometry for Semiquantitative Assessment of High Heparin Concentrations: A Feasibility Study in Healthy Volunteers

Abstract Background and Aims To date, thromboelastometry has not been investigated as an assay to monitor profound heparin anticoagulation, such as is required for a safe cardiopulmonary bypass (CPB). The..

Read More
thumbnail
0 comment

Role of Venoarterial Extracorporeal Membrane Oxygenation as a Procedural Support Tool in Cardiovascular Instability: A Case Series

Abstract The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasing worldwide. Patients with cardiogenic shock were the first indication for VA-ECMO according to the Extracorporeal Life Support Organization (ELSO)..

Read More
thumbnail
0 comment

Venopulmonary extracorporeal life support: An Extracorporeal Life Support Organization registry analysis

Abstract Background There is a paucity of data informing on the current use, adverse events, outcomes, and prognostic drivers for patients receiving venopulmonary extracorporeal life support (VP ECLS). We aimed..

Read More
thumbnail
0 comment

Postoperative reduction in thrombin generation induced by elevated levels of tissue factor pathway inhibitor in cardiac surgery: a prospective observational…

Abstract Purpose Tissue factor pathway inhibitor (TFPI) is an intrinsic anticoagulant factor, and its plasma concentration is elevated by heparin administration. Because several hours are required to return to normal..

Read More
thumbnail
0 comment

Gender Disparity in Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest

Abstract Objectives:  Establishing an effective “chain of survival” for out-of-hospital cardiac arrest (OHCA) requires addressing gender disparities, which have been reported in both prehospital and in-hospital treatments. However, evidence of..

Read More
thumbnail
0 comment

Flow benefits of pediatric arterial cannulae versus introducer sheaths as distal perfusion catheters in venoarterial extracorporeal membrane oxygenation

Abstract Objective We test the hypothesis that pediatric arterial (“peds art”) cannulae as distal perfusion catheters (DPCs) for venoarterial extracorporeal membrane oxygenation provide more favorable distal limb hemodynamics than introducer..

Read More
thumbnail
0 comment

The Contemporary Landscape of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation

Abstract SINCE THE FIRST lung transplant in 1963 and the introduction of extracorporeal membrane oxygenation (ECMO) as a bridge to transplant (BTT) in 1977, both have advanced remarkably. Lung transplantation is now..

Read More
thumbnail
0 comment

Astrocyte Activation in the Hippocampus Following Cardiopulmonary Bypass in a Rat Model: A Pilot Study

Abstract Background: Delirium after cardiac surgery is associated with poor outcomes. Cardiopulmonary bypass (CPB) increases blood-brain barrier (BBB) permeability and neuroinflammation, contributing to delirium. While microglial activation after CPB has..

Read More
thumbnail
0 comment

Impact of different blood flow modes on hemodynamic environment, thrombosis risk and oxygen transport of oxygenators: A numerical simulation study

Abstract Background and Objective Pulsatile blood flow is considered more potential for delivering hemodynamic energy and enhancing microcirculatory perfusion in patients compared to non-pulsatile flow in ECMO. This study aims..

Read More
thumbnail
0 comment

Outcomes after postcardiotomy venoarterial extracorporeal membrane oxygenation in young patients: An individual patient data meta-analysis

Abstract Objective We aimed to evaluate the early and midterm mortality of young patients treated for cardiogenic shock with venoarterial extracorporeal membrane oxygenation (VA-ECMO) after adult cardiac surgery. Methods Studies..

Read More
thumbnail
0 comment

Platelet Transfusion Thresholds for Children Supported by Extracorporeal Membrane Oxygenation: The Extracorporeal Membrane Oxygenation Hemostatic Transfusions in Children (ECSTATIC) Feasibility…

Abstract Objectives:  To evaluate the feasibility of randomizing children on extracorporeal membrane oxygenation (ECMO) to one of two prophylactic platelet transfusion thresholds. Design:  Randomized controlled trial. Setting:  Ten ECMO centers..

Read More
thumbnail
0 comment

Role of Non-catecholamines Vasopressors in the Management of Vasoplegic Syndrome after Cardiopulmonary Bypass: A Scoping Review

Abstract Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II, and ascorbic acid...

Read More