Abstract Background: Extracorporeal membrane oxygenation (ECMO) is a complex procedure affecting both the risk of thrombosis and bleeding. High-quality data to personalize anticoagulation management in ECMO are lacking, resulting in..
Read MoreAbstract OBJECTIVE. Extracorporeal membrane oxygenation (ECMO) is increasingly widely used in pediatric respiratory failure. Despite playing a key part in patient management during ECMO, the role of radiology is not widely..
Read MoreAbstract Rationale and Objectives To evaluate the quality and value of contrast-enhanced (CE) chest- and abdominal computed tomography (CT) and CT angiography in neonates, children, and adults undergoing extracorporeal membrane..
Read MoreAbstract The concept of left ventricular unloading has its foundation in heart physiology. In fact, the left ventricular mechanics and energetics represent the cornerstone of this approach. The novel sophisticated..
Read MoreAbstract OBJECTIVES: To determine the actual cost and drivers of the cost of an extracorporeal cardiopulmonary resuscitation (E-CPR) care cycle. PERSPECTIVE: A time-driven activity-based costing study conducted from a healthcare..
Read MoreAbstract The clinical tolerance of extracorporeal membrane oxygenation (ECMO) membrane changes in acute respiratory distress syndrome (ARDS) patients under veno-venous ECMO (VV-ECMO) has not been reported. The aim of this..
Read MoreAbstract Blood-contact medical devices are indispensable for clinical interventions, yet their susceptibility to thrombosis and bacterial infections poses substantial risks to treatment efficacy and patient well-being. This study introduces a..
Read MoreAbstract The threshold for packed red blood cell (pRBC) transfusion has been an important focus in the management of critically ill patients since the publication of randomized control trials (RCTs)..
Read MoreAbstract Despite technological advances in left ventricular assist device (LVAD) technology, which have made survival competitive with heart transplantation at 2 years, right ventricular failure (RVF), with an incidence of..
Read MoreAbstract Introduction Simulation-based learning has become an essential element in entry-level perfusion education. While the use of simulation has been demonstrated to improve patient outcomes, few institutions possess the budgetary..
Read MoreAbstract Objective: To describe characteristics associated with survival for pediatric patients with an oncologic diagnosis or hematopoietic cell transplant (HCT) supported with extracorporeal membrane oxygenation (ECMO). Design: Multicenter, retrospective study...
Read MoreAbstract Optimal oxygen management during pediatric cardiopulmonary bypass (CPB) is unknown. We previously demonstrated an increase in cortical mitochondrial reactive oxygen species and decreased mitochondrial function after CPB using hyperoxic..
Read MoreAbstract Objectives Heart donation after circulatory death was recently reintroduced in the United States with hopes of increasing donor heart availability. We examined its national use and outcomes. Methods The..
Read MoreAbstract Acute kidney injury is a common complication following cardiac surgery (CSA-AKI). Serum creatinine levels require a minimum of 24–48 h to indicate renal injury. Nevertheless, early diagnosis remains critical..
Read MoreAbstract Aims Patients with symptomatic aortic valve stenosis are efficiently treated by aortic valve replacement (AVR), using a biological or mechanical valve. For some patients with mechanical valves, the metallic..
Read MoreAbstract Acute kidney injury represents a significant threat in cardiac surgery regarding complications and costs. Novel preventive approaches are needed, as the therapeutic modalities are still limited. As experimental studies..
Read MoreAbstract Purpose Oxygen delivery (DO2) and its monitoring are highlighted to aid postoperative goal directed therapy (GDT) to improve perioperative outcomes such as acute kidney injury (AKI) after high-risk cardiac..
Read MoreAbstract Critically ill patients sometimes require tandem application of extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) which is easier and cheaper. We aimed to transform the kidney..
Read MoreAbstract OBJECTIVES Postoperative organ dysfunction is common after cardiac surgery, particularly when cardiopulmonary bypass (CPB) is used. The Sequential Organ Failure Assessment (SOFA) score is validated to predict morbidity and..
Read MoreCerebral Autoregulation: A Target for Improving Neurological Outcomes in Extracorporeal Life Support
Abstract Despite improvements in survival after illnesses requiring extracorporeal life support, cerebral injury continues to hinder successful outcomes. Cerebral autoregulation (CA) is an innate protective mechanism that maintains constant cerebral..
Read MoreAbstract Heart failure with preserved ejection fraction (HFpEF) constitutes approximately 50% of heart failure (HF) cases, and encompasses different phenotypes. Among these, most patients with HFpEF exhibit structural heart changes,..
Read MoreAbstract Unfractionated heparin (UFH) was uncovered in 1916, has been used as an anticoagulant since 1935, and has been listed in the World Health Organization's Model List of Essential Medicines...
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) circuit priming procedures are crucial for removing air bubbles and the albumin in priming solution is thought to create a protective layer against blood exposure..
Read MoreAbstract Right ventricular (RV) assessment has been a long time endeavour but difficult for many reasons, anatomic physiologic and imaging. Recently, new approaches have allowed better understanding of the how-to..
Read MoreAbstract Purpose: The outcomes of immunocompromised patients with cardiogenic shock treated with venoarterial extra‑corporeal membrane oxygenation (VA‑ECMO) are seldom documented, making ECMO candidacy decisions challeng‑ing. This study aims (1) to..
Read MoreAbstract In a recent issue of Intensive Care Medicine, we read with great interest the article by Moyon et al. [1] who retro-spectively studied the outcomes of immunocompromised patients with..
Read MoreAbstract Introduction: Adequate cerebral protection for aortic reoperation is challenging and optimal technique is still controversial. Case Report: We report a hybrid cannulation approach to achieve safe cerebral protection..
Read MoreAbstract Introduction: Cardiac disease is associated with a risk of death, both by the cardiac condition and by comorbidities. The waiting time for surgery begins with the onset of symptoms..
Read MoreAbstract Objective To verify the impact of preoperative levosimendan on patients with severe left ventricular dysfunction (ejection fraction <35%) undergoing isolated coronary artery bypass grafting. Design A meta-analysis. Setting Hospitals...
Read MoreAbstract Objective To evaluate the efficacy and safety of intrapleural perfusion with hyperthermic chemotherapy (IPHC) in treating malignant pleural effusion (MPE). Methods PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure..
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