Yearly Archives: 2026

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Predicting intraoperative transfusion volumes of blood products in cardiovascular surgery: a retrospective study

Abstract Background and Objectives Red blood cells are often overprepared for surgery, leading to waste and increased costs, despite the need for cross-matching tests. This study aimed to develop a..

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Restoring the Morphology and Function of Damaged Red Blood Cells

Abstract Red blood cells (RBCs) play a crucial role in delivering oxygen to tissues with their distinctive shape. However, the mechanisms underlying cellular deformation and rupture due to stress, which..

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Extracorporeal Membrane Oxygenation (ECMO) for Acute Respiratory Distress Syndrome (ARDS) During Pregnancy: A Systematic Review

Abstract Acute respiratory distress syndrome (ARDS) in pregnancy is rare but life-threatening. Extracorporeal membrane oxygenation (ECMO) has been used as rescue therapy in refractory cases, though evidence remains limited. This..

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ECMO patient energy requirements: A descriptive, retrospective cohort study

Abstract Background Indirect calorimetry (IC) in patients receiving extracorporeal membrane oxygenation (ECMO) is complicated. This study presents a novel IC method for this population and compares energy expenditure (EE) from..

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Standard coagulation assays during cardiopulmonary bypass predict post-bypass levels in cardiac surgery

Abstract Background Cardiac surgery with cardiopulmonary bypass (CPB) requires precise hemostasis management to limit postoperative bleeding. Fibrinogen, platelet count, and pro-coagulant factors guide transfusion decisions, yet Clauss fibrinogen measurement during..

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Perioperative tight glucose control regimens for preventing surgical site infections following cardiac surgery-a systematic review and metanalysis of randomized controlled…

Abstract Background Perioperative hyperglycemia is common during cardiac surgery and has been linked to an increased risk of surgical site infections (SSIs). However, the benefits of perioperative tight glucose control..

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ECMO decannulation is associated with dynamic changes in coagulation profiles: an exploratory, nested cohort study

Abstract Background ECMO-associated coagulopathy is a common phenomenon in patients undergoing ECMO therapy. However, data on coagulation trajectories in the post ECMO decannulation period are limited. This study aimed to..

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Marginal Band Collapsing: Structural Insights Into Shear-Induced Platelet Activation Relevant to Circulatory Assist Devices

Abstract Shear-induced platelet activation and receptor shedding in mechanical circulatory support (MCS) paradoxically increase risks of thrombosis and bleeding. Although flow cytometry commonly assesses platelet activation and receptor expression, correlations..

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Comparative Analysis of Pressure Drop (Δp): Hemodynamic Performance of Three Commercial Oxygenators During Cardiopulmonary Bypass

Abstract Background The membrane oxygenator is a critical component of extracorporeal circulation (ECC), whose performance directly depends on its structural architecture. Differences in fiber geometry and winding patterns lead to..

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ECOS-TCS - 23/24 June

The next edition of the International ECOS-TCS Congress is planned on June 23-24, 2026 in Paris, at the Institut du Cerveau, at the Pitié Salpêtrière Hospital. Extracorporeal Organ Support (ECOS)..

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Paris pediatric ecmo course - 15/19 June

Paris pediatric ecmo course June 15-19, 2026 Language will be English. Intensive teaching program: 5 days The program will be interactive, with lectures, case studies and a lot of time devoted to..

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Integrating Continuous Renal Replacement Therapy into Ex-situ Normothermic Liver Machine Perfusion

Abstract Ex situ normothermic machine perfusion (NMP) of the liver has emerged as a dynamic preservation strategy, enabling the maintenance of metabolic activity and assessment of grafts prior to transplantation. Prolonged..

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Outcomes of Abdominal Exploration in ECMO-Supported Patients: A Multicenter ICU Cohort Study

Abstract Objectives Exploratory laparotomy, when required as a treatment for abdominal complications of post–extracorporeal membrane oxygenation (ECMO) initiation, carries a high mortality rate that approaches 80% to 100%. However, studies..

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Temporary mechanical support in fulminant myocarditis: prognostic factors and clinical implications from the FULLMOON study

Abstract Background: Temporary mechanical circulatory support (t‑MCS) is increasingly used in fulminant myocarditis (FM), yet long‑term outcomes and risk factors remain poorly defined.   Methods: From the FULLMOON international cohort..

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Association Between Hospital-Level Volume of Extracorporeal Membrane Oxygenation and Complications: A Clustered, Mixed-Effect Analysis of the Extracorporeal Life Support Organization…

Abstract Objective:  Extracorporeal membrane oxygenation (ECMO) has been used to provide pulmonary and circulatory support in patients with ongoing critical illness. Studies investigating whether an association exists between ECMO center-volume..

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Artificial Intelligence–Driven Monitoring for Early Detection and Management of Harlequin Syndrome During Veno-Arterial ECMO Support

Abstract Background: Harlequin syndrome, also referred to as differential hypoxemia or North South syndrome, is a critical yet underrecognized complication of venoarterial extracorporeal membrane oxygenation and hybrid configurations such as ECpella...

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Bleeding in Patients With Infarct-Related Cardiogenic Shock: A DanGer Shock Substudy

Abstract Background The microaxial flow pump (mAFP) has demonstrated improved outcomes in selected patients with ST-segment elevation acute myocardial infarction and cardiogenic shock (STEMI-CS). However, its use has been associated..

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Biomarkers of multi-organ dysfunction in ECMO: prognostic signposts for palliative transitions

Abstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..

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Correlation of anticoagulation assays with bleeding during extracorporeal membrane oxygenation at a tertiary pediatric hospital

Abstract Introduction Due to anticoagulation during Extracorporeal Membrane Oxygenation (ECMO), patients face a higher risk of bleeding. This study aimed to assess the correlation between anticoagulation assays and hemorrhage in..

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Nationwide outcomes of cardiac surgery in patients with cannabis use disorder

Abstract Objective To characterize in-hospital morbidity and mortality in patients undergoing cardiovascular surgery with and without cannabis use disorder (CUD) using a national database. Methods Between 2016 and 2018, 846,837..

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Impact of surgical non-technical skills on clinical outcomes: systematic review

Abstract Background Deficiencies in non-technical skills (NTS) such as leadership and communication can lead to intraoperative inefficiency and error. However, the relationship between these skills and patient-level outcomes has yet..

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Awake vs. Sedated Cannulation for Extra-Corporeal Membrane Oxygenation in Patients with COVID-19 Induced Acute Respiratory Distress Syndrome

Abstract Background: Veno-venous extra-corporeal membrane oxygenation (ECMO) cannulations are mostly performed while patients are heavily sedated and mechanically ventilated. For patients with acute respiratory distress syndrome (ARDS), cannulating for ECMO while..

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Development and Evaluation of a Multimodal Debriefing Dashboard for Virtual Reality Cardiac Arrest Simulation

Abstract Introduction  Wearable sensing technologies incorporated into virtual reality (VR) headsets can provide a number of unique, previously hidden insights into individual and team learning and performance in complex environments...

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Severe hyperammonemia following coronary artery bypass grafting

Abstract Background Hyperammonemia is a rare but serious cause of encephalopathy, commonly associated with hepatic dysfunction. However, non-hepatic hyperammonemia (NHHA) can arise due to impaired gastrointestinal transit, urease-producing organisms, and..

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Twenty-eight cases of thalassemia: A retrospective study of autologous and allogeneic erythrocyte transfusions during cesarean section

Abstract Aim Erythrocytes from patients with thalassemia might be susceptible to hemolysis during recycling and washing. Therefore, autologous erythrocyte transfusion using erythrocytes from parturient women with thalassemia has been suggested..

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Association of Vitamin C Administration with Postoperative Delirium After Cardiac Surgery with Cardiopulmonary Bypass: A Single-Center Retrospective Exploratory Cohort Study

Abstract Objectives: Oxidative stress after cardiac surgery may disrupt the blood–brain barrier and contribute to postoperative delirium (POD). Although associations between oxidative stress and POD are recognized, whether vitamin C (VC)..

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How I monitor lung function during mechanical ventilation and veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome

Abstract Purpose of review  Mechanical ventilation (MV) is central to the management of acute respiratory distress syndrome (ARDS). In refractory cases, veno-venous extracorporeal membrane oxygenation (VV-ECMO) can provide adequate gas..

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Delirium after cardiac surgery incidence and perioperative risk factors in a prospective cohort

Abstract Background Delirium is an aetiologically nonspecific cerebral syndrome characterised by disturbances in consciousness, attention, perception, cognition, memory, psychomotor activity, emotion, and the sleep–wake cycle. It frequently occurs after cardiac..

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Quantitative Evaluation of Hemolysis Under Excessive Static and Repeated Negative Pressure During Blood Handling

Abstract Background: Hemolysis, defined as the rupture of red blood cells (RBCs) with the release of hemoglobin into plasma, is a common concern during blood collection and extracorporeal circulation. Although..

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The Rate of Platelet Count Decline on Cardiopulmonary Bypass With a Sorin S5 Roller Pump

Abstract To the Editor: I wish to share the results of a retrospective observational correlation study I completed recently. While it is well established that the platelet count is negatively..

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