Abstract Extracorporeal life support (ECLS) is increasingly used to rescue patients with refractory respiratory failure, cardiogenic shock and/or cardiac arrest. Acute brain injury during ECLS is common and associated with..
Read MoreAbstract Background Heparin-induced thrombocytopenia (HIT) in patients who undergo cardiac surgery presents unique diagnostic and management challenges due to universal perioperative heparin exposure, postoperative platelet kinetics, and the high prevalence..
Read MoreAbstract Background Post-cardiotomy cardiogenic shock (PCCS) remains one of the most lethal complications of cardiac surgery, with high in-hospital mortality despite major improvements in operative techniques, and intensive care management...
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) supports patients with end-stage heart and lung disease awaiting transplantation. In pulmonary hypertension, veno-arterial ECMO (VA-ECMO) is common but linked to vascular complications and limited..
Read MoreAbstract Background The study aimed to identify the patient-related and procedure-related factors independently associated with the development of device-associated health care-associated infections (DA-HAIs) in cardiac intensive care unit (CICU), specifically..
Read MoreAbstract Background In adult patients receiving veno-venous Extracorporeal Membrane Oxygenation (VV ECMO), cardiovascular performance plays a critical role in determining oxygen delivery, organ perfusion and safe titration of extracorporeal support...
Read MoreAbstract The respiratory exchange ratio (RER), defined as the ratio of carbon dioxide (CO2) production to oxygen (O2) consumption, may be a non-invasive and continuously measurable alternative to lactate for..
Read MoreAbstract Background Thoracoabdominal aortic aneurysm (TAAA) repair is associated with significant risks of blood loss and organ ischemia. This study evaluates the efficacy of a novel, modified Extracorporeal Circulation (mECC)..
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) is an established life support technique for refractory acute cardiorespiratory failure in children and adult patients. However, ECMO support is provided only by specialized..
Read MoreAbstract Background Traumatic major limb amputations require urgent intervention to prevent irreversible tissue necrosis and life-threatening systemic complications due to warm ischemia. We aim to demonstrate the efficacy of extracorporeal..
Read MoreAbstract Background Prolonged mechanical ventilation (PMV) after major cardiac surgery is associated with increased morbidity, mortality, and healthcare utilization. Objectives To determine independent perioperative predictors of PMV and assess its..
Read MoreAbstract Objectives Cardiopulmonary bypass (CPB) is essential to cardiac surgery but is associated with organ injury from non-physiological perfusion. Goal-directed perfusion (GDP) has emerged as a physiology-based strategy to optimize..
Read MoreAbstract Background Refractory end-stage lung failure may benefit from extracorporeal life support (ECLS) as a bridge to lung transplantation. Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is indicated in patients who..
Read MoreAbstract Objectives Although hyperthermic perfusion (arterial outlet temperature >37°C) during cardiopulmonary bypass (CPB) is associated with acute kidney injury (AKI), the impact of body temperature at the time of separation..
Read MoreAbstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..
Read MoreAbstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..
Read MoreAbstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..
Read MoreAbstract The Extracorporeal Life Support Organization (ELSO) has progressively transformed its guideline framework to meet the increasing clinical, scientific, and operational demands of modern extracorporeal life support. Since its establishment..
Read MoreAbstract Background Takotsubo cardiomyopathy (TTC) is an episode of transient left ventricular (LV) dysfunction affecting 2.1% of patients with suspected acute ST-segment elevation myocardial infarction. Case Summary A 61-year-old woman..
Read MoreAbstract As adult programs of newer anthrombotic agents, such as those directed against FXIa, are underway, there is both a pressing need and a great opportunity to optimize the design,..
Read MoreAbstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...
Read MoreAbstract Background Patients undergoing cardiac surgery are at high risk of severe immediate postoperative complications. Predicting immediate postoperative adverse events remains challenging owing to the complex and nonlinear interplay of..
Read MoreAbstract It seems logical to divide the macrocirculation into systemic and pulmonary circulation, but it is rare in clinical practice to further subdivide microcirculation into systemic and pulmonary microcirculation. Both..
Read MoreAbstract Floating thrombi of the aortic arch constitute rare yet highly consequential lesions with high embolic risk for which optimal management remains debated. Conventional surgical management typically requires deep hypothermic..
Read MoreAbstract Background Lung-protective ventilation in acute respiratory distress syndrome (ARDS) can lead to hypercapnia, an independent risk factor for increased mortality. Extracorporeal CO2 removal (ECCO2R) enables further reduction of ventilator intensity,..
Read MoreAbstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..
Read MoreAbstract Objectives Previous studies have shown that Buckberg microplegia reduces the need for intraoperative blood transfusion by minimizing hemodilution. However, this approach has been largely understudied in the context of..
Read MoreAbstract Objectives Whether patients with kidney failure who undergo cardiac surgery have a survival advantage with previous kidney transplantation is unclear. This study evaluated long-term outcomes after cardiac surgery for..
Read MoreAbstract Background Acute kidney injury (AKI) is frequent in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), largely due to the severity of cardiogenic shock and multiorgan failure. Renal replacement..
Read MoreAbstract Background Nearly 500,000 open-heart operations are performed annually in the United States, with complications such as postcardiotomy cardiogenic shock (PCCS) occurring in 2–9% of cases. Extracorporeal membrane oxygenation (ECMO)..
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