Monthly Archives: marzo 2026

Perfusfind S.L.

Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis..

Perfusfind S.L.

Abstract The global rise in anticoagulant use has increased the number of major bleeding events that warrant timely and effective pharmacologic reversal. Reversal strategies should be informed by the pharmacodynamic..

Perfusfind S.L.

Abstract Importance  Neurodevelopmental impairments are common in children with congenital heart disease. Objectives  To compare neurodevelopmental outcomes by cardiac diagnosis and identify associations between medical and social factors and early neurodevelopmental outcomes..

Perfusfind S.L.

Abstract Cardiopulmonary bypass (CPB) activates a well-characterised systemic inflammatory response that contributes substantially to postoperative morbidity and mortality, particularly in high-risk patient subgroups. CytoSorb® (CytoSorbents Corporation, Princeton, NJ) is a..

Perfusfind S.L.

Abstract Open-heart surgery with cardiopulmonary bypass (CPB) is a high-risk procedure with significant morbidity and mortality. CPB, tissue injury, blood loss, endotoxemia and ischemia–reperfusion injury induce a pronounced systemic inflammatory..

Perfusfind S.L.

Abstract Introduction Intensive care units (ICUs) represent high-risk environments for adverse events (AEs). Preventing these events requires a solid understanding of their epidemiology based on standardized and validated methodologies. The..

Perfusfind S.L.

Abstract Background: Invasive ventilation saves lives but carries major risks, including ventilation-associated lung damage and long-term functional impairment. Data from recent studies compel reassessment of the evidence for every step of..

Perfusfind S.L.

Abstract Extracorporeal life support (ECLS) components designed to reduce clot formation have been developed, but thrombosis remains a significant challenge, requiring systemic anticoagulation. To address this, we evaluated a nitric..

Perfusfind S.L.

Abstract Objective To assess the non-inferiority of topical intrapericardial tranexamic acid (TXA) versus intravenous TXA for efficacy and safety in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods In..

Perfusfind S.L.

Abstract Transfusions are one of the most common procedures performed in the hospital setting, but the frequency of adverse events is often not recognized. These transfusion adverse events include transfusion..

Perfusfind S.L.

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) provides crucial circulatory and respiratory support in refractory cardiogenic shock and cardiac arrest. However, peripheral VA-ECMO increases left ventricular (LV) afterload through retrograde..

Perfusfind S.L.

Abstract Purpose of review The use of life-support therapies like extracorporeal membrane oxygenation (ECMO), mechanical circulatory systems (MCS), and continuous renal replacement therapy (CRRT) creates a complex and dynamic metabolic..

Perfusfind S.L.

Abstract Intestinal ischemia/reperfusion (I/R) injury is a critical clinical syndrome precipitated by the restoration of blood flow following intestinal ischemia, a common occurrence in perioperative settings such as abdominal aortic..

Perfusfind S.L.

Abstract Background Despite recent advancements in cardiopulmonary resuscitation (CPR), the prognosis of out-of-hospital cardiac arrest (OHCA) remains poor. Extracorporeal cardiopulmonary resuscitation (ECPR) offers potential benefits to improve outcomes of patients..

Perfusfind S.L.

Abstract Patient Blood Management (PBM) has evolved from a transfusion-centered practice to a structured, patient-focused perioperative strategy aimed at improving surgical outcomes while preserving blood resources. In the operating room,..

Perfusfind S.L.

Abstract Objective Prolonged ischemic time remains a major barrier to donor use and is strongly associated with primary graft dysfunction in heart transplantation. We evaluated whether intraoperative recipient metabolic adequacy,..

Perfusfind S.L.

Abstract Background Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lymphocytes in the spleen..

Perfusfind S.L.

Abstract Background Discovered in 1938, haptoglobin is a liver-produced α2-glycoprotein that binds free hemoglobin, mitigating its toxic effects, and serves as a biomarker for hemolysis. The current study, under the..

Perfusfind S.L.

Abstract Background: Heparin-induced thrombocytopenia (HIT) in patients who undergo cardiac surgery presents unique diagnostic and management challenges due to universal perioperative heparin exposure, postoperative platelet kinetics, and the high prevalence..

Perfusfind S.L.

    Surgical Procurement of a Donor Heart with Complex Congenital and Venous Anomalies: PLSVC, Coronary Sinus Dilation, RA Aneurysm, and Patent Ductus Arteriosus (PDA) In thoracic organ transplantation, discovering..

Perfusfind S.L.

    Partial Heart and Lung Transplantation: Maximizing Donor Organ Utilization Through Two-Recipient Transplantation Partial heart and lung transplantation is an innovative organ utilization strategy that allows transplantation of thoracic..

Perfusfind S.L.

      Managing aortic and pulmonary root enlargement in donor organs requires a meticulous, proactive strategy to ensure structural stability before implantation into an emergency recipient. Utilizing a double..

Perfusfind S.L.

Abstract Background Jehova′s Witnesses refuse the administration of allogenic blood products for religious reasons. This stance represents a special challenge for the perioperative management and requires individualized ethically sensitive and..

Perfusfind S.L.

Abstract Background Congenital heart disease surgery includes intricate structures that are perhaps hard to completely understand by traditional two-dimensional shapes. Individualised, centre-based three-dimensional (3D) heart models may enhance structural imaging and..

Perfusfind S.L.

Abstract Rationale Circadian rhythms affect cardiovascular function, and the timing and severity of stroke and myocardial infarction (commonly known as a heart attack). Afternoon cardiac surgery may improve outcomes by..

Perfusfind S.L.

Abstract Background Oxygenator failure during cardiopulmonary bypass (CPB) is a rare but potentially catastrophic intraoperative event that can result in sudden hypoxemia and neurological injury if not promptly recognized and..

Perfusfind S.L.

Abstract Background Cardiac index (CI) and mean arterial pressure (MAP) are concurrent determinants of renal perfusion. Hypotension is associated with acute kidney injury (AKI), but clinical trials focused solely on..

Perfusfind S.L.

Abstract We describe a case of establishing cardiopulmonary bypass (CPB) before general anesthesia in a person who has an obstructive right atrial myxoma protruding into the right ventricle (RV). A..

Perfusfind S.L.

Abstract Background Thromboelastometry is often used to guide coagulation management, but validation outside cardiac surgery is limited. We evaluated correlations between thromboelastometry parameters and conventional laboratory tests in noncardiac patients..

Perfusfind S.L.

Abstract Purpose This study aimed to evaluate the clinical effects of sodium bicarbonate Ringer’s solution(BRS) as a priming fluid for cardiopulmonary bypass (CPB). Methods A total of 159 patients undergoing..