Yearly Archives: 2025

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Chlorhexidine-alcohol compared with povidone-iodine-alcohol skin antisepsis protocols in major cardiac surgery: a randomized clinical trial

Abstract Purpose Whether skin disinfection of the surgical site using chlorhexidine-alcohol is superior to povidone-iodine-alcohol in reducing reoperation and surgical site infection rates after major cardiac surgery remains unclear. Methods..

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Crossing borders to meet cardiac surgical needs: A scoping review on patients seeking cardiac surgery abroad

Abstract Background Over 100 countries do not have a local cardiac surgeon, whereas capacity, coverage, or cultural constrains may limit access to cardiac surgical care in-country. This scoping review aims..

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Pre-operative transcranial Doppler ultrasound assessment of cerebral collateral circulation in children undergoing veno-arterial extracorporeal membrane oxygenation or cardiac surgery

Abstract Children requiring veno-arterial extracorporeal membrane oxygenation (VA ECMO) or cardiac surgery often undergo cervical cannulation or carotid artery clamping, which can interrupt cerebral circulation. Inadequate collateral flow through the..

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Inferior vena cava thrombosis in patients undergoing extracorporeal membrane oxygenation: a case series and literature review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is mainly used for support of patients with cardiopulmonary collapse. The increasing use of ECMO has shown promising outcomes; however, it still carries the..

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Extracorporeal membrane oxygenation: unmet needs and perspectives

Abstract Extracorporeal Membrane Oxygenation (ECMO) has become an essential lifesaving intervention for individuals with severe cardiovascular and respiratory failure. Its application is expanding across several therapeutic contexts, surpassing conventional indications...

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Extracorporeal-CPR Versus Conventional-CPR for Adult Patients in Out of Hospital Cardiac Arrest– Systematic Review and Meta-Analysis

Abstract Objective Extracorporeal cardiopulmonary resuscitation (ECPR) utilizes veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in cardiac arrest patients to reduce the risk of mortality and multiorgan dysfunction from systemic hypoperfusion. We aimed..

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The effects of blood cell salvage on transfusion requirements after decannulation from veno-venous extracorporeal membrane oxygenation: an emulated trial analysis

Abstract Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is an established supportive therapy for severe and potentially reversible acute respiratory distress syndrome (ARDS) [, ]. Despite improving patient outcomes, including reducing mortality, VV-ECMO..

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Normothermic cardiopulmonary bypass and beating heart surgery for renal cell cancer with tumor thrombus extension into inferior vena cava and…

Abstract Purpose Management of renal cell carcinoma (RCC) with inferior vena cava (IVC) extension is one of the greatest challenges in urology. The gold standard treatment includes extracorporeal circulation and..

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Transcatheter aortic‐valve implantation with or without on‐site cardiac surgery: The TRACS trial

Abstract Background Transcatheter aortic valve implantation (TAVI) has emerged as an effective and safe treatment for patients with symptomatic aortic stenosis. The indication to TAVI should be agreed upon by..

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Cerebral Protection in Pediatric Cardiac Surgery

Abstract Cardiac surgery, both adult and pediatric, has developed very rapidly and impressively over the past 7 decades. Pediatric cardiac surgery, in particular, has revolutionized the management of babies born..

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Percutaneous Femoral Venous Cannulation—How to Do It

Percutaneous femoral venous cannulation is a vital skill for cardiac surgeons, especially in complex procedures such as redo sternotomy and ECMO.  This video demonstrates the key technical steps for insertion..

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Anticoagulation management during veno-venous ECMO support because of ARDS: Single-center experience

Abstract Background Patients with severe acute respiratory distress syndrome (ARDS) show a high mortality rate of up to 60 %. In such cases, extracorporeal membrane oxygenation (ECMO) support is often required,..

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Anticoagulation in Extracorporeal Membrane Oxygenation for Trauma: Striking a Balance

Abstract Extracorporeal membrane oxygenation in a venovenous configuration (VV-ECMO) is increasingly recognized as an important therapeutic option for patients with severe acute respiratory distress syndrome (ARDS). Accumulating scientific evidence as well..

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A Guide to Contrast-Enhanced Computed Tomography in Adult Patients Supported With Extracorporeal Membrane Oxygenation

Abstract Veno-arterial extracorporeal membrane oxygenation (VA ECMO) fundamentally alters patient physiology and blood flow relevant to contrast delivery for computed tomography (CT) imaging. Here, we present a comprehensive guide to..

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Minimizing Acute Kidney Injury in Pediatric Cardiac Surgery: Incidence, Early Detection, and Preemptive Measures

Abstract Background Acute kidney injury (AKI) poses a significant challenge in pediatric cardiac surgery, having a profound impact on patient morbidity and mortality. This study aims to determine the incidence..

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Thrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery

Abstract Thrombin generation (TG) is reduced after cardiac surgery using cardiopulmonary bypass (CPB), contributing to coagulopathy and bleeding. Plasma transfusion or four-factor prothrombin complex concentrate (PCC) are commonly used to..

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MiECC reloaded

Abstract The concept of mini cardiopulmonary bypass (mini-CPB) has been introduced in clinical practice from early 2000 for advancing perfusion technology aiming to improve cardiac surgical results. The diversity of custom-made..

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Impact of macrohemodynamic manipulations during cardiopulmonary bypass on finger microcirculation assessed by photoplethysmography signal components

Abstract Objective.  Continuous monitoring of the hemodynamic coherence between macro and microcirculation is difficult at the bedside. We tested the role of photoplethysmography (PPG) to real-time assessment of microcirculation during..

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A model for predicting AKI after cardiopulmonary bypass surgery in Chinese patients with normal preoperative renal function

Abstract Objective To develop and validate a predictive model for acute kidney injury (AKI) after cardiopulmonary bypass (CPB) surgery in Chinese patients with normal preoperative renal function. Method From January..

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The association between changes in cerebral hemodynamics and cerebrovascular complications during ECMO treatment in neonates

Abstract Objective To investigate whether changes in cerebrovascular hemodynamic parameters during extracorporeal membrane oxygenation (ECMO) treatment in neonates are associated with the occurrence of cerebrovascular complications. Methods This study selected..

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The early decline in platelet count is associated with increased adverse outcomes in non heparin-induced thrombocytopenia pediatric patients undergoing VA-ECMO

Abstract Introduction The impact of non heparin-induced thrombocytopenia on the clinical outcomes for pediatric cardiac surgery patients who required veno-arterial extracorporeal membrane support (VA-ECMO) for failure to wean from cardiopulmonary..

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Hemostatic Outcome Definitions in Pediatric Extracorporeal Membrane Oxygenation: Challenges in Cohorts From Rotterdam (2019–2023) and Melbourne (2016–2022)

Abstract Objectives:  To determine if a priori standardization of outcome hemostatic definitions alone was adequate to enable useful comparison between two cohorts of pediatric extracorporeal membrane oxygenation (ECMO) patients, managed..

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Platelet-sparing properties of aprotinin

Abstract BACKGROUND  Cardiac surgery involving cardiopulmonary bypass (CPB) is associated with the risk of acquired coagulopathy, including dysregulated fibrinolysis, which can result in life-threatening bleeding complications. Aprotinin, an antifibrinolytic agent,..

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Use of extracorporeal blood purification therapies in sepsis: the current paradigm, available evidence, and future perspectives

Abstract Background Sepsis is the result of a dysregulated immune response to infection and is associated with acute organdysfunction. The syndrome’s complexity is contingent upon the underlying pathology and individual..

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Current status of routine use of veno-arterial extracorporeal membrane oxygenation during lung transplantation

Abstract Introduction Recently, there has been growing experience with utilizing a veno-arterial extracorporeal membrane oxygenator (VA ECMO) routinely during lung transplantation procedures. Yet, there is a lack of consensus on..

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Early extracorporeal membranous oxygenation and burn excision in severe burn and inhalation injury

Abstract Introduction Extracorporeal membranous oxygenation (ECMO) as a salvage therapy for patients with severe acute respiratory distress syndrome (ARDS) has been described but experience is limited in burn cases. Few..

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ECMO-weaning facilitated by neurally adjusted ventilatory assist (NAVA): a case for principal clarification

Abstract The use of veno-venous extracorporeal membrane oxygenation (VV-ECMO) has become increasingly prevalent, particularly in respiratory disease pandemics such as H1N1-influenza and SARS-CoV-2. This surge has emphasized the importance of..

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Total reversal of the pulmonary circulation (RPC) induced by peripheral cannulation for veno-arterial ECMO in a patient with aortic and…

Abstract This case report details a rare instance of total reversal of the pulmonary circulation (RPC) in a 56-year-old male patient on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) during emergency..

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Pulse Pressure During VA-ECMO Support and Neurologic Outcomes: Worth Getting Pumped Up About?

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for the management of refractory cardiogenic shock. Although VA-ECMO can stabilize hemodynamics and improve systemic flow, morbidity, and mortality on support..

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