Yearly Archives: 2025

Perfusfind S.L.

Abstract Background Children who undergo cardiac surgery may require postcardiotomy extracorporeal membrane oxygenation (ECMO). Although morbidities are considerable, our understanding of outcome determinants is limited. We evaluated associations between patient..

Perfusfind S.L.

Abstract Background Excessive perioperative bleeding is associated with major complications in cardiac surgery, resulting in increased morbidity, mortality, and cost. Methods An international expert panel was convened to develop consensus..

Perfusfind S.L.

Abstract The blood vessel network transfers gas and nutrients throughout the body. In addition, vascular cells contribute to essential functions such as coagulation, immune regulation, angiogenesis and tissue repair, and..

Perfusfind S.L.

Abstract Around one-quarter of all patients undergoing cardiac procedures, particularly those on cardiopulmonary bypass, develop cardiac surgery-associated acute kidney injury (CSA-AKI). This complication increases the risk of several serious morbidities..

Perfusfind S.L.

Abstract Background Postcardiotomy cardiogenic shock (PCCS) in cardiac surgery is associated with a high rate of morbidity and mortality. Beside other therapeutic measures (e.g. intraaortic balloon pump (IABP)), extracorporeal life..

Perfusfind S.L.

Abstract Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is associated with fewer neurological complications and decreased mortality compared to veno-arterial (VA) ECMO in neonatal respiratory failure. The Crescent right atrial (RA)..

Perfusfind S.L.

Abstract Mortality remains elevated during venoarterial extracorporeal membrane oxygenation support (VA-ECMO) for cardiogenic shock and the role of inflammation is uncertain. By using the neutrophil-to-lymphocyte ratio (NLR), we investigated inflammatory..

Perfusfind S.L.

Abstract Background Near-infrared spectroscopy (NIRS) enables a non-invasive measurement of tissue oxygen saturation (StO2) in regions illuminated by near-infrared lights. Vascular occlusion test (VOT) serves as a model to artificially..

Perfusfind S.L.

Abstract Objective Wide interhospital variation exists in cardiac surgical postoperative transfusion rates. We aimed to compare transfusion rates at 2 hospitals and identify the institutional practice factors, unrelated to patient..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) can support patients with severe cardiorespiratory failure presenting with hypoxia who would otherwise have not survived. Patient selection for ECMO is challenging and relies on..

Perfusfind S.L.

Abstract Background It has long been held that the safe duration of hypothermic circulatory arrest (HCA) is at least 25 to 30 minutes. However, this belief is based primarily on..

Perfusfind S.L.

Abstract Objective To systematically evaluate the impact of the Trendelenburg position on hemodynamic parameters in adult patients. Design Systematic literature review and meta-analysis using PubMed and Medline. Setting All prospective..

Perfusfind S.L.

Abstract Hypothermic oxygenated perfusion (HOPE) is an emerging technique for donor heart preservation that is currently being studied in multiple clinical trials with promising results. When compared to HOPE for..

Perfusfind S.L.

Abstract Background Survival for cardiac arrest remains poor, and the use of extracorporeal cardiopulmonary resuscitation (ECPR) has been suggested as a potential therapy to improve outcomes. Harefield Hospital has been performing..

Perfusfind S.L.

Abstract Background Acute lung injury and acute respiratory failure are frequent complications of cardiogenic shock and are associated with increased morbidity and mortality. Even with increased use of temporary mechanical..

Perfusfind S.L.

Abstract Background Systemic hypothermia with bilateral antegrade selective cerebral perfusion (ASCP) is the preferred cerebral protective strategy for type A aortic dissection surgery. The optimal ASCP flow rate remains uncertain..

Perfusfind S.L.

Abstract Background Today, with wars raging in Ukraine and the Middle East, the demand for blood is high. Despite this, few companies produce the necessary equipment to draw, store, and..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) is a common, heterogeneous, multifactorial condition, which is part of the overarching syndrome of acute kidney diseases and disorders. This condition's incidence highest in low-income..

Perfusfind S.L.

Abstract Severe accidental hypothermia can lead to cardiac arrest. The most efficient method of resuscitating and warming is by ECMO (Extracorporeal Membrane Oxygenation). While the convention is to use VA..

Perfusfind S.L.

Abstract Epinephrine, the standard treatment for anaphylaxis, is a lifesaving medication that can cause detrimental complications due to wrong-dose or wrong-route errors. Although the known toxicities of epinephrine such as..

Perfusfind S.L.

Abstract Background.  The global shortage of solid organs for transplantation is exacerbated by high demand, resulting in organ deficits and steadily growing waiting lists. Diverse strategies have been established to..

Perfusfind S.L.

Abstract Introduction: The factors contributing to blood loss during hemodialysis (HD) procedures remain underexplored. This study aimed to quantify blood loss during HD and identify the potential factors associated with it. ..

Perfusfind S.L.

Abstract Over the past two decades, extracorporeal membrane oxygenation (ECMO) has been increasingly used to support critical patients with cardiac and respiratory failure who fail to respond to conventional management...

Perfusfind S.L.

Since 1991, the ‘European Board of Cardiovascular Perfusion (EBCP)’ has played a vital role in the European healthcare system by overseeing and promoting the field of cardiovascular clinical perfusion. Through..

Perfusfind S.L.

Abstract The systemic inflammatory response after cardiopulmonary bypass has been widely studied. However, there is a paucity of studies that focus on the local inflammatory changes that occur in the..

Perfusfind S.L.

Abstract BACKGROUND: Andexanet alfa (andexanet) is the only Food and Drug Administration–approved antidote for direct FXa (factor Xa) inhibitors but has been reported to cause resistance to unfractionated heparin (UFH)...

Perfusfind S.L.

Abstract Cardiac surgery patients are potentially exposed to an acute inflammatory host response with a huge release of both pro- and anti-inflammatory cytokines both through intrinsic (e.g., tissue damage, endothelial..

Perfusfind S.L.

Abstract Background The study objective was to determine the impact of cardiopulmonary bypass perfusion modalities on cerebral hemodynamics and clinical outcomes in congenital cardiac surgery patients stratified by acyanotic versus..

Perfusfind S.L.

Abstract Background Reliable myocardial protection is essential for a good outcome after arterial switch operation. Patients and Methods We evaluated 56 neonates with arterial switch operation in this retrospective study...

Perfusfind S.L.

Abstract Background While the number of cardiac surgery programs in sub-Saharan Africa are increasing, it is still insufficient. With only 0.08 pediatric cardiac surgeons per million people, few cardiac centers..