Yearly Archives: 2025

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The Role of Cannula Design in Optimizing CPB Flow Dynamics

In the complex world of cardiopulmonary bypass (CPB), where precision, safety, and efficiency govern every aspect of patient care, the significance of flow dynamics cannot be overstated. While the primary..

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How to Maintain Splanchnic Perfusion: A Practical Clinical Guide

Introduction Splanchnic perfusion refers to the blood flow through the splanchnic circulation, which supplies the gastrointestinal organs including the stomach, intestines, liver, pancreas, and spleen. Maintaining adequate splanchnic blood flow..

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Flow Matters: Revisiting Pulsatility in Cardiopulmonary Bypass.

Introduction The heart is nature’s pulsatile pump, delivering rhythmic surges of blood critical not only for oxygen transport but also for maintaining vascular health. Cardiopulmonary bypass, a lifesaving intervention, often..

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Rethinking Blood Pump Safety: The Case for Nonocclusive Pressure-Regulated Pumps

In cardiopulmonary bypass (CPB), roller and centrifugal pumps have been the mainstays for decades, each with unique benefits and challenges. However, these traditional blood pumps come with inherent pressure-related risks..

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Biocompatible and Miniaturized Cardiopulmonary Bypass Circuits: Shaping the Future of Cardiac Surgery

Introduction Cardiopulmonary bypass (CPB) is fundamental to modern cardiac surgery, allowing surgeons to perform complex procedures on a still and bloodless heart. However, traditional CPB systems are associated with complications..

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Procalcitonin as a biomarker for postoperative pneumonia: a study on dynamics following cardiopulmonary bypass in adults

Abstract Objective Postoperative pneumonia (POP) frequently complicates cardiac surgery that involves cardiopulmonary bypass (CPB). This study aimed to assess the diagnostic utility of procalcitonin (PCT) for identifying pneumonia after CPB-assisted..

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Outcomes and Prognostic Markers in Extracorporeal Cardiopulmonary Resuscitation: 10-Year Experience from a Rural Tertiary Care Center

Abstract Background: Extracorporeal cardiopulmonary resuscitation (eCPR) is a method for initiation of cardiopulmonary bypass during resuscitation of a patient with refractory cardiac arrest to support end-organ perfusion. This retrospective study evaluates..

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Platelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines

Abstract Importance  Platelet transfusion is a frequent procedure with benefits and risks. Objective  To provide recommendations in adult and pediatric populations in whom platelet transfusions are commonly performed. Evidence Review  Grading of Recommendations..

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Risk factors for postoperative hypothermia in non-cardiac surgery patients: a systematic review and meta-analysis

Abstract Background Postoperative hypothermia seems to be a common problem in surgical patients but is easily ignored. This study aimed to identify risk factors for postoperative hypothermia in non-cardiac surgery..

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Patient perspectives on surgical handover quality: a mixed-methods survey

Abstract Background In-hospital handover of patient care is an essential but high-risk professional activity that often lacks transparency for patients. The purpose of this survey was to gain insight into..

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Extracorporeal membrane oxygenation support: palliative care integration – patient experience and quality of life

Abstract Objective The pattern and timing of palliative care utilisation and end-of-life characteristics in extracorporeal membrane oxygenation (ECMO)-supported patients remain underused. We wanted to share our centre’s experience. Methods This is an..

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Measurement and interpretation of central venous pressure: a narrative review

Abstract Introduction Central venous pressure has been a key component of haemodynamic monitoring for several decades, but its clinical utility is still debated. While central venous pressure has been used..

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Effect of Deep Hypothermia (18°C) on Dioxygen Metabolism During Pulmonary Thromboendarterectomy Surgery

Abstract Objectives The aim of this physiological pilot study was to investigate the effect of deep hypothermia on oxygen extraction (OE) and consumption (VO2) in normothermic conditions (36-37°C), and at..

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Impact of psycho-educational interventions on patients undergoing Coronary Artery Bypass Grafting Surgery

Abstract Background Postoperative period of Coronary Artery Bypass Grafting can be challenging, with physical and psychological problems and symptoms. We conducted this study to explore the effect of a psycho-educational..

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Leveraging pediatric veno-arterial extra corporeal membrane oxygenation parameters to identify early risk factors for mortality

Abstract Objective Pediatric Veno-Arterial Extra Corporeal Membrane Oxygenation (VA ECMO) can be a lifesaving technology; however, it is associated with high mortality. A successful VA ECMO course requires attention to..

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Knowledge Gain and the Impact of Stress in a Fully Immersive Virtual Reality–Based Medical Emergencies Training With Automated Feedback: Randomized…

Abstract Background: A significant gap exists in the knowledge and procedural skills of medical graduates when it comes to managing emergencies. In response, highly immersive virtual reality (VR)–based learning environments..

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Comparison of two different autotransfusion devices: An ex-vivo study

Abstract Introduction During surgery, blood is recovered from the surgical field and the autotransfusion device separates and washes the red blood cells (RBC’s) after which these can be retransfused to..

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Changing minds, saving lives: how training psychological safety transforms healthcare

Abstract Psychological safety is a crucial component in highly functioning healthcare teams, enabling every member to speak up, take innovative risks and admit mistakes without fear of personal attack or..

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The Role of Venoarterial Ecmo in the Management of Sepsis-Induced Cardiomyopathy and Refractory Shock: An Analytic Review

Abstract Sepsis-induced cardiomyopathy is a severe complication seen in patients with refractory septic shock, characterized by cardiac dysfunction due to an overwhelming inflammatory response secondary to infection. Despite its reversible..

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A Novel Predictive Score Model for Successful Weaning From Mechanical Circulatory Support in Patients With Cardiogenic Shock

Abstract Background Clinical evidence regarding predictors of successful weaning from mechanical circulatory support (MCS) is lacking. This study aimed to create a simple risk score to predict successful weaning from..

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Training and Assessing Teamwork in Interprofessional Virtual Reality–Based Simulation Using the TeamSTEPPS Framework: Protocol for Randomized Pre-Post Intervention Study

Abstract Background: Interprofessional teamwork is essential for patient outcomes in emergency medicine; yet, effective training in this area is scarce. Virtual reality (VR) provides a promising, resource-efficient solution for simulating..

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Effect of Dexmedetomidine on Cerebrovascular Carbon Dioxide Reactivity During Pediatric Cardiac Surgery With Cardiopulmonary Bypass

Abstract Objective To assess the effects of dexmedetomidine (DEX) on cerebrovascular autoregulation in children with congenital heart disease (CHD) using transcranial color-coded duplex sonography (TCCD). Design Randomized controlled trial. Setting..

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Acid–Base Status in Critically Ill Patients: Physicochemical vs. Traditional Approach

Abstract Background/Objectives: Critically ill patients can often present acid–base alterations. The aim of this study was to evaluate the prevalence and the time-course of acid–base alterations on intensive care unit..

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Hemolysis in Extracorporeal Membrane Oxygenation: A Comparative Analysis of Venovenous Versus Venopulmonary Arterial Approaches

Abstract Venopulmonary arterial (VPA) extracorporeal membrane oxygenation (ECMO) is emerging as an alternative to traditional venovenous (VV) ECMO for respiratory failure. This study compares rates of hemolysis and acute kidney..

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Transferring health professionals social and cognitive skills: key findings from a qualitative investigation

Abstract Background Research shows that simulation-based training can increase knowledge and skills among pregraduate healthcare students, that simulation-based training of technical skills places the participants higher on the learning curve..

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Refractory hypoxaemia on extracorporeal CO2R: Case report and literature review

Abstract Extracorporeal carbon dioxide removal (ECCO2R) is increasingly used in clinical practice as a means of facilitating protective mechanical ventilation and reducing the risk of ventilator-induced lung injury (VILI) in patients..

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Association of Oxygenation Targets and Mortality in Critical Care Patients Following Cardiac Surgery: A Retrospective Cohort Study

Abstract Objective To investigate the relationship between arterial oxygen partial pressure (PaO2) and all-cause mortality of post–cardiac surgery patients. Design A retrospective cohort study based on the Medical Information Mart..

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Deep insight into cytokine storm: from pathogenesis to treatment

Abstract Cytokine storm (CS) is a severe systemic inflammatory syndrome characterized by the excessive activation of immune cells and a significant increase in circulating levels of cytokines. This pathological process..

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We’re no longer flying blind—resuscitation in the ECPR era

Abstract As extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly utilized for refractory cardiac arrest in adults, we learn significantly more about resuscitation in ways that were not applicable, or even available..

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Prognostic Value of Perioperative Near-Infrared Spectroscopy Monitoring for Postoperative Acute Kidney Injury in Pediatric Cardiac Surgery: A Systematic Review

Abstract Introduction Postoperative acute kidney injury (AKI) is a common postoperative complication in cardiac surgery, with varying reported incidences and prognostic factors. Renal hypoperfusion is believed to be a key..

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