Yearly Archives: 2024

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20-Year follow-up and comparison of valved conduits used for right ventricular outflow tract reconstruction: single-centre, propensity score match analysis

Abstract OBJECTIVES Surgical repair of complex congenital heart defects with hypoplasia or atresia of the right ventricular outflow tract (RVOT) may require pulmonary valve implantation or replacement during the primary..

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Temperature and Neurologic Outcomes in Neonates Undergoing Cardiac Surgery: A Society of Thoracic Surgeons Study

Abstract Background There is significant variability in postoperative neurological injury rates in patients with , with early injuries impacting long-term neurodevelopmental outcomes; therefore, there is an urgent need for identifying effective..

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Neurosurgical Procedures in Patients Requiring Extracorporeal Membrane Oxygenation

Abstract OBJECTIVES:  Extracorporeal membrane oxygenation (ECMO) is often withheld in patients with significant neurologic injury or recent neurosurgical intervention due to perceived futility. Studies of neurosurgical interventions before or during..

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Outcomes of Multiorgan Heart Transplant Between Donation After Circulatory Death and Brain Death

Abstract There is insufficient data on the outcomes of donation after circulatory death (DCD) multiorgan transplant that includes heart. The primary objective of this study is to compare the overall..

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HeartMate 3 Ventricular Assist Device in a Single-Ventricle and Single-Lung Patient Palliated With a Bidirectional Glenn

Abstract We describe a 15 year old patient with failing second-stage single-ventricle palliation and left pulmonary artery thrombosis successfully supported with HeartMate 3 ventricular assist device and a Fontan completion..

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Central Venous Oxygen Saturation for Estimating Mixed Venous Oxygen Saturation and Cardiac Index in the ICU: A Systematic Review and…

Abstract OBJECTIVES:  The objectives of our systematic review and meta-analyses were to determine the diagnostic accuracy of central venous oxygen saturation (Scvo2) in estimating mixed venous oxygen saturation (Svo2) and..

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Artificial intelligence: The future of cardiothoracic surgery

Abstract John McCarthy first used the term artificial intelligence (AI) in a conference at Dartmouth College in 1956. He discussed “the science and engineering of making intelligent machines.” This paved..

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Extracorporeal Membrane Oxygenation Support in Adult Patients with Calcium Channel Blocker Toxicity - An ELSO Registry Analysis

Abstract Background: Calcium channel blocker (CCB) toxicity presents a significant mortality risk, highlighting the need for effective treatment strategies such as ECMO. This study analyzes ELSO registry data to determine the..

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Functional and Social Recovery and Outcomes After Extracorporeal Membrane Oxygenation Support in COVID-19 Patients

Abstract With the COVID pandemic, veno-venous (VV) extracorporeal membrane oxygenation (ECMO) was implanted in many patients around the world. Data regarding follow-up and recovery of patients who are placed on..

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Awake insertion of transplant-bridging veno-arterial extracorporeal membrane oxygenation in a shocked patient with severe thrombocytopenia: a case report.

Abstract Background: Extracorporeal membrane oxygenation is an effective life support technology in treating patients with cardiorespiratory failure. It could be used as a bridge to recovery, potentially improving patient outcomes due..

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Multiple Pediatric Extracorporeal Membrane Oxygenation Runs and Futility. What Are the Limits?

Abstract Despite high mortality rates, pediatric extracorporeal membrane oxygenation (ECMO) redeployments are frequently discussed in everyday clinical care. We aim to investigate predictors of mortality in those patients. Clinical data..

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Ten Hour Donor Heart Ischemic Time with 10ºC Static Storage

Abstract Utilization of 10ºC static storage safely extended both ischemic time and travel radius in heart transplantation. A 57-year-old man with ischemic cardiomyopathy, a left ventricular assist device (LVAD), and..

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A novel miniaturized roller pump circuit for simulation of extracorporeal circulation

Abstract OBJECTIVES Extracorporeal circulation induces pronounced effects on haemostasis and rheology. To study these, an ex vivo simulation model is an attractive alternative but often requires large amounts of blood. We sought..

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SQUIRE-SIM (Standards for Quality Improvement Reporting Excellence for SIMulation)

Abstract Introduction  With increased incorporation of simulation-based methodologies into quality improvement activities, standards for reporting on simulation-specific elements in healthcare improvement research are needed. Methods  We followed established consensus process..

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Operating Room Extubation for Patients Undergoing Cardiac Surgery: A National Society of Thoracic Surgeons Database Analysis

Abstract Background The utility of operating room extubation (ORE) after cardiac surgery over fast-track extubation (FTE) within 6 hours remains contested. We hypothesized ORE would be associated with equivalent rates..

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An endothelium membrane mimetic antithrombotic coating enables safer and longer extracorporeal membrane oxygenation application

Abstract Thrombosis and plasma leakage are two of the most frequent dysfunctions of polypropylene (PP) hollow fiber membrane (PPM) used in extracorporeal membrane oxygenation (ECMO) therapy. In this study, a..

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VA-ECMO as a support therapy in massive acute pulmonary embolism treated with catheter-directed thrombolysis

Abstract Introduction: Acute pulmonary embolism (PE) leads to increased pulmonary vascular resistance and right ventricular afterload, resulting in right ventricular dysfunction (RVD). Stratification is crucial to early identify patients with elevated..

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Survival After Extracorporeal Cardiopulmonary Resuscitation Based on In-Hospital Cardiac Arrest and Cannulation Location: An Analysis of the Extracorporeal Life Support…

Abstract Objectives:  Explore whether extracorporeal cardiopulmonary resuscitation (ECPR) mortality differs by in-hospital cardiac arrest location and whether moving patients for cannulation impacts outcome. Design:  Retrospective cohort study. Setting:  ECPR hospitals..

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Hydrogel-coated and active clearance chest drains in cardiac surgery: real-world results of a single-center study

Abstract Purpose Cardiac surgery patients require chest drains for postoperative fluid drainage. Innovations in this field include chemical drain coating and manual clot extraction systems, aiming to provide reduced clotting..

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Acquired antithrombin deficiency in adult patients with postcardiotomy extracorporeal membrane oxygenation

Abstract Introduction This study aimed to investigate the relationship between acquired antithrombin deficiency in patients undergoing postcardiotomy extracorporeal membrane oxygenation (PC-ECMO) and thromboembolic or haemorrhagic events such as bleeding, peripheral..

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Risk factors for allogeneic red blood cell transfusion in adult spinal deformity surgery

Abstract Study Design Retrospective study. Purpose To investigate the risk factors for allogeneic red blood cell (RBC) transfusion in adult spinal deformity (ASD) surgery. Overview of Literature Studies have not..

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Complement system activation: bridging physiology, pathophysiology, and therapy

Abstract The complement system is a set of over 50 proteins that constitutes an essential part of the innate immune system. Complement system activation involves an organized proteolytic cascade. Overactivation..

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Early endothelial injury in cardiogenic shock patients on venoarterial ECMO

Abstract Endothelial injury is usually considered as a major com-ponent of the systemic inflammatory response observed during veno-arterial extracorporeal membrane oxygena-tion (VA-ECMO) support. Yet, few data are avail-able to support..

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2023 ISHLT Guidelines for Mechanical Circulatory Support

Abstract THE 2023 International Society for Heart and Lung Transplantation (ISHLT) guidelines for mechanical circulatory support (MCS) supersede the 2013 guidelines published a decade ago, incorporating substantial developments in device technology and..

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The Role of Veno-Arterial Extracorporeal Membrane Oxygenation in Amniotic Fluid Embolism: A Case Report

Abstract Introduction: Amniotic fluid embolism (AFE) is a catastrophic complication of pregnancy with high mortality rate. It is an inflammatory response leading to cardiovascular collapse. We present a case of successful..

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Relation between antithrombin-III activity and activated clotting time for cardiopulmonary bypass

Abstract Heparin resistance (HR) is observed before cardiopulmonary bypass (CPB), despite with normal antithrombin III (AT-III) levels. The relationships between preoperative AT-III activity and activated clotting time (ACT) after the..

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Hemodynamic Effects and Clinical Outcomes of Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation (LAVA-ECMO) in Cardiogenic Shock

Abstract Background: Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) is a novel mechanical cardiocirculatory support strategy that provides robust cardiocirculatory support and simultaneous left and right atrial venting via a multi-fenestrated..

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Hemodynamic Support in Sepsis

Abstract Sepsis is a dysregulated host response to infection responsible for life-threatening organ dysfunction.1  Along with early antimicrobial administration and source control, correction of hemodynamic derangements is a crucial aspect of..

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FISIOLOGIA DO SANGUE - AULA 79

Prof. Elio Carvalho é Biomédico, Microbiologista e Perfusionista pela Unicamp, CLAP e SBCEC. É perfusionista do Hospital de Clínicas da Unicamp e Coordenador do Curso da Unicamp de Perfusionistas. É..

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