Yearly Archives: 2023

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Heart transplant patients from socioeconomically distressed communities face higher mortality, organ failure risk

Abstract People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared..

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Outcomes of a modified, low-cost, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) for elective, periprocedural support of high-risk percutaneous cardiac interventions:…

Abstract Introduction High-risk procedures in interventional cardiology include a wide spectrum of clinical and anatomical scenarios related to a higher periprocedural morbidity and mortality. The prophylactic use of short-term mechanical..

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Pilot Testing of a Lightweight, Pulmonary Assist System in an Ambulatory Sheep Model of Destination Therapy Respiratory Support

Abstract A new, lightweight (2.3 kg), ambulatory pulmonary assist system (PAS) underwent preliminary evaluation in ambulatory sheep. The PAS was purposefully designed for long-term extracorporeal respiratory support for chronic lung..

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A Simple Formula for Predicting Ventricular Distension With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Left ventricular (LV) distention is a known complication of venoarterial extracorporeal membrane oxygenation (VA-ECMO) due to increased afterload stress. The consequences of LV distension include elevated pulmonary venous pressures leading to pulmonary edema and increased wall..

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Accelerated Hemocompatibility Testing of Rotary Blood Pumps

Abstract Ex vivo hemocompatibility testing is a vital element of preclinical assessment for blood-contacting medical devices. Current approaches are resource intensive; thus, we investigated the feasibility of accelerating hemocompatibility testing by standardizing..

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A Paradigm Shift in Heart Preservation: Improved Post-transplant Outcomes in Recipients of Donor Hearts Preserved with the SherpaPak System

Abstract Traditional ice storage has been the historic standard for preserving donor’s hearts. However, this approach provides variability in cooling, increasing risks of freezing injury. To date, no preservation technology..

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Long-Term Outcome and Prognosis of Noninfectious Thoracic Aortitis

Abstract Background  is a group of disorders characterized by the inflammation of the aorta. The large-vessel  are the most common causes of aortitis.  long-term outcomes are not well known. Objectives The purpose..

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Bridging the gap: safety and outcomes of intensivist-led ECMO retrievals

Abstract Purpose: Most extracorporeal membrane oxygenation (ECMO) cannulations are performed by cardiothoracic surgeons (CTS). Due to an increase in utilization of ECMO and limited availability of CTS, there is a mismatch..

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Widening care gap in VAD therapy

Abstract Background The removal of the HeartWare ventricular assist device (HVAD) due to pump malfunctions and inferior outcomes compared to HeartMate 3 (HM3) in adults has created a care gap..

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Transfusion of red blood cells in venoarterial extracorporeal membrane oxygenation: A multicenter retrospective observational cohort study

Abstract Background Evidence-based recommendations for transfusion in patients with venoarterial extracorporeal membrane oxygenation (VA ECMO) are scarce. The current literature is limited to single-center studies with small sample sizes, therefore..

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Bilateral Femoral Cannulation Is Associated With Reduced Severe Limb Ischemia-Related Complications Compared With Unilateral Femoral Cannulation in Adult Peripheral Venoarterial…

Abstract Objectives:  Peripheral venoarterial extracorporeal membrane oxygenation (ECMO) with femoral access is obtained through unilateral or bilateral groin cannulation. Whether one cannulation strategy is associated with a lower risk for limb ischemia remains unknown...

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Standard calculations guide

(Thanks to Navin Kumar for letting us share) Preface: Working as a perfusionist is a highly challenging and rewardingcareer path. The educational standards are high, and theprofession appeals to those..

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O melhor caminho para chegar na Perfusão - Aulao 67

  Prof. Elio Carvalho é Biomédico, Microbiologista e Perfusionista pela Unicamp, CLAP e SBCEC. É perfusionista do Hospital de Clínicas da Unicamp e Coordenador do Curso da Unicamp de Perfusionistas...

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A PERFUSÃO EM OUTRO PATAMAR - Aulao 66

  Prof. Elio Carvalho é Biomédico, Microbiologista e Perfusionista pela Unicamp, CLAP e SBCEC. É perfusionista do Hospital de Clínicas da Unicamp e Coordenador do Curso da Unicamp de Perfusionistas...

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Use of Perioperative Extracorporeal Membranous Oxygenation in Pulmonary Endarterectomy Cases: A Systematic Review and Meta-Analysis

Abstract Introduction Pulmonary endarterectomy (PEA) is known to be a curative intervention for chronic thromboembolic pulmonary hypertension (CTEPH). Its complications include endobronchial bleeding, persistent pulmonary arterial hypertension, right ventricular failure,..

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Naming and Unnaming in the Extracorporeal Membrane Oxygenation Literature

Abstract We are grateful for the readers’ interest and suggestions relevant to our original contribution entitled “Pulmonary Artery Dual-Lumen Cannulation Versus Two Cannula Percutaneous Extracorporeal Membrane Oxygenation Configuration in Right..

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The Obesity Paradox in Patients in Need of ECMO

Abstract  The Obesity Paradox in Patients in Need of ECMO

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3D printed biomedical devices and their applications: A review on state-of-the-art technologies, existing challenges, and future perspectives

Abstract , also known as Additive manufacturing (AM), has emerged as a transformative technology with applications across various industries, including the medical sector. This review paper provides an overview of..

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A multicentre, propensity score matched analysis comparing a valve-sparing approach to valve replacement in aortic root aneurysm: Insight from the…

Abstract OBJECTIVES Our goal was to evaluate the outcome of valve-sparing root replacement (VSRR) and to compare the outcomes to those of patients having composite valve–graft conduit aortic root replacement..

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Increasing obesity is associated with lower postoperative bleeding in coronary bypass patients

Abstract Objective Despite inherent comorbidities, obese cardiac surgical patients paradoxically had shown lower morbidity and mortality, although the nature of this association is still unclear. Thus, the authors intended in..

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A quality improvement initiative to increase adult ECMO decision-making abilities in a perfusion education program: The use of 3D ECMO…

Abstract Introduction Adult and pediatric ECMO procedures have been increasingly established as conventional life-saving modalities in critical care services across the world. Since 2017, a multidisciplinary team of program advisors..

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A formula for survival in surgery

Abstract Surgeons continuously work to ensure that their patients receive safe, timely and high-quality care, often in challenging circumstances. The strive for excellence may often manifest itself in the surgeons’..

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Rotational Thromboelastometry–Guided Use of Synthetic Blood Products in Cardiac Transplant Patients: A Retrospective Before-After Study

Abstract Objectives Viscoelastic  assays, such as rotational  (ROTEM), are used increasingly in cardiac surgery to guide transfusion decisions. After separation from  (CPB), achieving  rapidly is the main goal before chest closure. The authors hypothesized..

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The Introduction of an MR-Conditional Prototype for Cardiopulmonary Bypass Support: Technical Aspects and System Requirements

Abstract Introduction: The use of cardiopulmonary bypass (CBP; also known as a heart-lung machine) in newborns with complex congenital heart defects may result in brain damage. Magnetic resonance imaging (MRI) assessments..

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Anticoagulation for cardiopulmonary bypass, Part 2: alternatives and pathological states

Abstract Pathophysiology There are two types of HIT, depending on the absence or presence of an immune mediation. Type 1 is a non-immune-mediated direct activation of platelets by heparin that..

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Validity and Utility of Early Parameters in TEG6s Platelet Mapping to Assess the Coagulation Status During Cardiovascular Surgery With Cardiopulmonary…

Abstract Background The aim of this retrospective observational study was to explore the early predictive parameters for maximum amplitude in the kaolin with heparinase (HKH) assay (MAHKH) of TEG6s Platelet Mapping..

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Clinical characteristics and outcome of Mycobacterium chimaera infections after cardiac surgery: systematic review and meta-analysis of 180 heater-cooler unit-associated cases

Abstract Objectives Since 2013, heater-cooler unit (HCU) associated  infections linked to a global outbreak have been described. These infections were characterised by high morbidity and mortality due to delayed diagnosis, as..

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Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications

Abstract Cardiac surgery is one of the highest-risk procedures, usually involving cardiopulmonary bypass and commonly inducing endothelial injury that contributes to the development of perioperative and postoperative organ dysfunction. Substantial..

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Efficacy of CytoSorb®: a systematic review and meta-analysis

Abstract Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac surgery or recovery after cardiac arrest. The aim of..

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Adverse renal effects associated with cardiopulmonary bypass

Abstract Cardiac surgery on cardiopulmonary bypass (CPB) is associated with postoperative renal dysfunction, one of the most common complications of this surgical cohort. Acute kidney injury (AKI) is associated with..

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