Perfusfind S.L.
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Joint EAPCI/ACVC expert consensus document on percutaneous ventricular assist devices

Abstract There has been a significant increase in the use of short-term percutaneous ventricular assist devices (pVADs) as acute circulatory support in cardiogenic shock and to provide haemodynamic support during..

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Alternative venous access sites for dual-lumen extracorporeal membrane oxygenation cannulation

Abstract OBJECTIVES Dual-lumen cannulas for veno-venous (VV) extracorporeal membrane oxygenation (ECMO) support are typically inserted in the right internal jugular vein (RIJV); however, some scenarios can make this venous route..

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Beta-blockade for the treatment of refractory hypoxaemia during venovenous extracorporeal membrane oxygenation: An in-silico study

Abstract Introduction Venovenous extracorporeal membrane oxygenation (VV ECMO) is used for refractory hypoxemia, although despite this, in high cardiac output states, hypoxaemia may persist. The administration of beta-blockers has been..

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Features and outcomes of female and male patients requiring postcardiotomy extracorporeal life support

Abstract Objectives Although cardiogenic shock requiring extracorporeal life support after cardiac surgery is associated with high mortality, the impact of sex on outcomes of postcardiotomy extracorporeal life support remains unclear..

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Sex differences in treatments and outcomes of patients with cardiogenic shock: a systematic review and epidemiological meta-analysis

Abstract Background Women are at higher risk of mortality from many acute cardiovascular conditions, but studies have demonstrated differing findings regarding the mortality of cardiogenic shock in women and men...

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The Association of Oxygen Delivery and Transfusion on Cardiopulmonary Bypass with Acute Kidney Injury

Abstract Objectives To estimate whether the association of transfusion and acute kidney injury (AKI) has a threshold of oxygen delivery below which transfusion is beneficial but above which it is..

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Storytelling of Myocarditis

Abstract In 1900, Fiedler first reported autopsy cases with peculiar inflammation of the myocardium, which he named interstitial myocarditis. He postulated an isolated cardiac inflammation of the myocardium in the..

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Impact of a bundle of care (intravenous iron, erythropoietin and transfusion metabolic adjustment) on post-operative transfusion incidence in cardiac surgery:…

Abstract Background Red blood cell (RBC) transfusions are frequent in patients after cardiac surgery. This study assessed whether a bundle of care including pre-operative and post-operative administration of  (EPO) with intravenous..

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A novel configuration for providing continuous renal replacement therapy via the ECMO circuit in VV ECMO without alarm adjustment

Abstract Background It is common for patients on venovenous extracorporeal membrane oxygenation (VV ECMO) to require continuous renal replacement therapy (CRRT). This can be done using separate vascular access for..

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Partial cardiopulmonary bypass through left thoracotomy for coarctation repair in children

Abstract Background A left thoracotomy approach is anatomically appropriate for childhood aortic coarctation; however, the pediatric femoral arteriovenous diameters are too small for cardiopulmonary bypass cannulation. We aimed to determine..

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Delayed cold-stored vs. room temperature stored platelet transfusions in bleeding adult cardiac surgery patients—a randomized multicentre pilot study (PLTS-1)

Abstract Background Platelets stored at 1–6 °C are hypothesized to be more hemostatically active than standard room temperature platelets (RTP) stored at 20–24 °C. Recent studies suggest converting RTP to cold-stored platelets..

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Antithrombin restriction in extracorporeal membrane oxygenation support (ARES): A multidisciplinary approach

Abstract Background:   Antithrombin (AT) replacement is occasionally utilized in the setting of extracorporeal membrane oxygenation (ECMO)-associated heparin resistance. Although past studies emphasized the high costs and limited clinical benefit..

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Criteria for Defining Stages of Cardiogenic Shock Severity

Abstract Background Risk-stratifying patients with  (CS) is a major unmet need. The recently proposed Society for Cardiovascular  and Interventions (SCAI) staging system for CS severity lacks uniform criteria defining each stage. Objectives..

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Analysis of the 2023 European Multidisciplinary Consensus Statement on the Management of Short-term Mechanical Circulatory Support of Cardiogenic Shock in…

Abstract DESPITE MEDICAL ADVANCEMENTS, mortality in cardiogenic shock (CS) remains unacceptably high.The decreased cardiac output resulting in impaired oxygen delivery characteristic of CS triggers a dismal cascade culminating in tissue..

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The prevalence of alloantibodies and ABO RhD blood groups in a cohort of Aboriginal and non-Aboriginal cardiac surgery patients from…

Abstract Introduction Limited evidence exists on the distribution of ABO RhD blood groups and prevalence and specificity of red blood cell (RBC) alloantibodies in Aboriginal and Torres Strait Islander peoples..

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A precise blood transfusion evaluation model for aortic surgery: a single-center retrospective study

Abstract Cardiac aortic surgery is an extremely complicated procedure that often requires large volume blood transfusions during the operation. Currently, it is not possible to accurately estimate the intraoperative blood..

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Treatment of Acute Kidney Injury: A Review of Current Approaches and Emerging Innovations

Abstract Acute kidney injury (AKI) is a complex and life-threatening condition with multifactorial etiologies, ranging from ischemic injury to nephrotoxic exposures. Management is founded on treating the underlying cause of..

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A Deep Learning Framework for Predicting Patient Decannulation on Extracorporeal Membrane Oxygenation Devices: Development and Model Analysis Study

Abstract Background: Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a therapy for patients with refractory respiratory failure. The decision to decannulate someone from extracorporeal membrane oxygenation (ECMO) often involves weaning trials..

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Impact of extracorporeal haemoadsorption during prolonged cardiopulmonary bypass on the incidence of acute kidney injury

Abstract The usage of cardiopulmonary bypass (CPB) in cardiothoracic surgery contributes to the activation of the inflammatory response. In certain cases, the systemic inflammatory response may be immoderate, leading to..

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Factor Eight Inhibitor Bypassing Activity as First-line Therapy for Coagulopathy in Cardiac Surgery

Abstract Objectives To compare the outcomes of factor eight inhibitor bypassing activity (FEIBA) versus fresh frozen plasma (FFP) as the primary treatment for postoperative coagulopathy in patients undergoing cardiac surgery...

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Comparing Outcomes of Post-Cardiotomy Cardiogenic Shock Patients: On-Site Cannulation vs. Retrieval for V-A ECMO Support

Abstract Background:    Post-cardiotomy cardiogenic shock (PCCS) remains a life-threatening complication after cardiac surgery. Extracorporeal membrane oxygenation (ECMO) represents the mainstay of mechanical circulatory support for PCCS; however, its availability..

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Practitioner dashboard feedback improves glycemic but not temperature compliance during cardiac surgery: A single center retrospective analysis

Abstract Study Objective To determine the association of practitioner dashboard feedback of intraoperative  and temperature control on maintenance of  and normothermia. Design Retrospective review. Setting Single  institution. Patients Patients over the age of..

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HEMA-Lysine-Based Cryogels for Highly Selective Heparin Neutralization

Abstract Unfractionated heparin (UFH) and its low-molecular-weight fragments (LMWH) are widely used as anticoagulants for surgical procedures and extracorporeal blood purification therapies such as cardiovascular surgery and dialysis. The anticoagulant..

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An Atraumatic Mock Loop for Realistic Hemocompatibility Assessment of Blood Pumps

Abstract Objective: Conventional mock circulatory loops (MCLs) cannot replicate realistic hemodynamic conditions without inducing blood trauma. This constrains in-vitro hemocompatibility examinations of blood pumps to static test loops that do..

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Anti-Xa-guided Anticoagulation With Unfractionated Heparin and Thrombosis During Extracorporeal Membrane Oxygenation Support: A Systematic Review and Meta-analysis

Abstract Objective The initiation of extracorporeal membrane oxygenation (ECMO) triggers complex coagulation processes necessitating systemic anticoagulation. Therefore, anticoagulation monitoring is crucial to avoid adverse events such as thrombosis and hemorrhage...

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Sex-specific troponin and creatine kinase thresholds after coronary bypass surgery

Abstract BACKGROUND The impact of sex-differences on the release of cardiac biomarkers after coronary artery bypass grafting (CABG) remains unknown. The aim of our study was to (a) investigate the..

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Multifaceted Intervention to Improve Patient Safety Incident Reporting in Intensive Care Units

Abstract Objectives  Patient safety incident reporting in our institution’s intensive care units (ICUs) had fallen 30% below national benchmarks during the COVID-19 pandemic. Underreporting diminishes awareness of risks and precludes..

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Risk prediction strategies using intraoperative physiological data in adults undergoing surgery: a systematic review study protocol

Abstract Postoperative mortality accounts for 7.7% of all global deaths, while postoperative complications increase 1-year mortality by 60%. Risk prediction models for postoperative complications and mortality can facilitate tailored risk..

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Twenty percent human albumin solution fluid bolus administration therapy in patients after cardiac surgery-II: a multicentre randomised controlled trial

Abstract Purpose After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may facilitate less fluid and vasopressor administration than FBT with crystalloids. We aimed to determine whether, after..

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Platelet-Rich Plasma Sequestration in Cardiac Surgery in a Jehovah's Witness

Abstract JEHOVAH'S WITNESSES (JW) refuse allogeneic blood transfusions because of their religious beliefs, a situation that poses significant challenges in the context of cardiac surgery, given that bleeding-related complications may..

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