Perfusfind S.L.

Abstract Background Antegrade cerebral perfusion (ACP) is widely used during congenital aortic arch reconstruction; however, variability persists regarding cannulation strategies. Direct innominate artery cannulation may simplify arterial access while maintaining..

Perfusfind S.L.

Abstract Background While minimally invasive techniques for simple septal defects have demonstrated comparable safety and efficacy to median sternotomy, clinical outcomes following minimally invasive repair of Tetralogy of Fallot (TOF)..

Perfusfind S.L.

Abstract Temporary mechanical circulatory support (tMCS) has evolved as a first-line treatment of cardiogenic shock refractory to medical therapy. In recent years, tMCS has been applied to bridge and precondition..

Perfusfind S.L.

Abstract Objectives To evaluate the feasibility of continuous bilateral lower-limb near-infrared spectroscopy (NIRS) monitoring as an adjunct to standard hourly neurovascular assessment (NVA) in patients receiving intra-aortic balloon pump (IABP)..

Perfusfind S.L.

Abstract Cardiac surgery-associated acute kidney injury (CS-AKI) increases short- and long-term mortality, progression to chronic kidney disease (CKD), and healthcare costs. Its pathogenesis is multifactorial—combining renal hypoperfusion, impaired oxygen delivery,..

Perfusfind S.L.

Abstract Objective To clarify how centrifugal blood pump-induced non-physiological shear stress affects platelet adhesion and aggregation, explaining the coexistence of thrombosis and bleeding during centrifugal pump support. Methods Blood samples..

Perfusfind S.L.

Abstract Background: Preoperative anaemia and perioperative transfusion are associated with adverse outcomes after cardiac surgery with cardiopulmonary bypass (CPB). Coronavirus disease 2019 (COVID-19) may induce persistent haematological and endothelial alterations...

Perfusfind S.L.

Abstract Background The incidence and risk factors of cardiac surgery–associated acute kidney injury (CS-AKI) are variable. We describe the incidence of severe postoperative CS-AKI (i.e., stage 2 or 3 AKI)..

Perfusfind S.L.

Abstract Background Perfusionists manage critical physiological parameters of cardiac surgery patients during cardiopulmonary bypass (CPB), requiring rapid, high-stakes decision-making under uncertainty. While artificial intelligence (AI) has the potential to enhance..

Perfusfind S.L.

Abstract Background: Dosing albumin to normalize colloid osmotic pressure is an underutilized strategy within the application of cardiopulmonary bypass. The negative sequelae of third-spacing and edema post-bypass are well known..

Perfusfind S.L.

Abstract Objective: To evaluate inflammatory biomarkers and lipidomic profiles in tracheal aspirates (TA) of infants with congenital heart disease (CHD), by pulmonary blood flow (Qp) high/low grouping at the time..

Perfusfind S.L.

Abstract Background: Hemofiltration during pediatric cardiopulmonary bypass (CPB) is essential to mitigate hemodilution, inflammatory responses, and postoperative complications. Conventional ultrafiltration (CUF) is widely practiced, but novel methods such as subzero..

Perfusfind S.L.

Abstract Introduction del Nido cardioplegia had not been commercially available in the United Kingdom prior to the DESTINY trial, a multi-centre individually randomised controlled trial to evaluate whether del Nido..

Perfusfind S.L.

Abstract Introduction: The global prevalence of morbid obesity is increasing, presenting challenges in cardiac surgery. Morbid obesity (body mass index ≥40 kg/m2) is associated with a high burden of cardiometabolic comorbidities..

Perfusfind S.L.

Abstract Objectives To identify a critical cardiopulmonary bypass (CPB) duration threshold predictive of a complicated postoperative course after elective cardiac surgery in the absence of technical complications and to find..

Perfusfind S.L.

Abstract Background: Allogenic blood product transfusion has well-documented risks and adverse outcomes. To limit perioperative transfusions for neonates and infants undergoing cardiac surgery, our institution launched a blood conservation program..

Perfusfind S.L.

Abstract Introduction Vasoplegic syndrome (VS) is a severe complication after cardiac surgery with cardiopulmonary bypass (CPB), characterised by vasodilation, hypotension and vasopressor dependence. Endothelial dysfunction, dysregulated nitric oxide signalling, inflammation..

Perfusfind S.L.

Abstract Objective We aimed to compare postoperative clinical outcomes between minimally invasive extracorporeal circulation (MiECC) and conventional extracorporeal circulation (CECC) in patients undergoing cardiac surgery. Methods We performed a meta-analysis..

Perfusfind S.L.

Abstract Profound, transient hypotension refractory to α1-agonists and increased bypass flow during cardioplegia administration (intermittent vasoplegia) is a well-recognized yet unexplained phenomenon in cardiac surgery. Retrograde cardioplegia has been shown..

Perfusfind S.L.

Abstract Objectives To evaluate the association between selective antegrade cerebral perfusion (SACP) flow ranges and early clinical outcomes in a large cohort of patients undergoing aortic arch surgery. Methods We..

Perfusfind S.L.

Abstract Up to 40% of cardiac surgery patients present with preoperative anemia, which is associated with significant risks and management challenges. This review highlights the increased perioperative risk attributable to..

Perfusfind S.L.

Abstract Introduction Cardiopulmonary bypass (CPB) provokes a systemic inflammatory response with important consequences for infants and children undergoing repair of congenital heart disease [, , ]. Inflammation engages overlapping coagulation..

Perfusfind S.L.

Abstract Myocardial protection during cardiopulmonary bypass relies on intermittent administrations of cardioplegia without continuous, tissue‑level feedback on myocardial oxygen supply and mitochondrial metabolic status. Extended near‑infrared spectroscopy (eNIRS) can enable..

Perfusfind S.L.

Abstract The gut microbiome has emerged as an important regulator of cardiovascular physiology through interconnected metabolic, immune, inflammatory, and endocrine pathways. Although the gut–heart axis has been extensively investigated in..

Perfusfind S.L.

Abstract Background We conducted a technical feasibility and safety study of intraureteric renal negative pressure treatment (rNPT) in patients with chronic kidney disease undergoing elective cardiac surgery with cardiopulmonary bypass..

Perfusfind S.L.

Abstract Background and Objectives Acute normovolemic hemodilution (ANH) is an established patient blood management strategy in cardiac surgery, but its effects on postoperative inflammatory biomarkers remain unclear. In this study,..

Perfusfind S.L.

Abstract Background Venoarterial (VA) extracorporeal membrane oxygenation (ECMO) is used to support refractory cardiogenic shock (CS) but may increase peripheral afterload. Invasive hemodynamic measurement and cardiopulmonary congestion during VA ECMO..

Perfusfind S.L.

Abstract Background Patients who undergo tandem extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) have a high risk of metabolic disturbances, malnutrition, and fluid imbalances. ECMO/CRRT tandem therapy..

Perfusfind S.L.

Abstract Purpose Tolvaptan sodium phosphate (TSP; Samtas®, Otsuka Pharmaceutical, Tokyo, Japan) is a novel intravenous aquaretic diuretic; however, evidence for its use in patients after cardiac surgery is limited. We..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is standard for cardiogenic shock, but outcomes remain limited. The BreathMo adult ECMO system with a maglev pump and a low-pressure drop oxygenator was developed...