Perfusfind S.L.
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Most Deaths in Low-Risk Cardiac Surgery Could Be Avoidable

Abstract It is observed that death rates in cardiac surgery has decreased, however, root causes that behave like triggers of potentially avoidable deaths (AD), especially in low-risk patients (less bias)..

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Endothelial Function in Patients With von Willebrand Disease

Abstract In patients with von Willebrand disease (vWD) the interest in age-related comorbidities has grown, because the life expectancy of these patients has increased. The research question of this study..

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Mycobacterium Chimaera in Heater-Cooler Devices: An Experience in A Tertiary Hospital in Spain

Abstract The aim of the study was to describe the Mycobacterium chimaera contamination in heater–cooler devices after the application of a protocol of cleaning and disinfection in a tertiary hospital. It was..

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The Minnesota mobile extracorporeal cardiopulmonary resuscitation consortium for treatment of out-of-hospital refractory ventricular fibrillation: Program description, performance, and outcomes

Abstract Background We describe implementation, evaluate performance, and report outcomes from the first program serving an entire metropolitan area designed to rapidly deliver extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation to patients..

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Practical Clinical Application of an Extracorporeal Carbon Dioxide Removal System in Acute Respiratory Distress Syndrome and Acute on Chronic Respiratory…

Abstract We retrospectively reviewed the medical records of 11 patients supported with a veno-venous low-flow extracorporeal carbon dioxide (CO2) removal (ECCO2R) device featuring a large gas exchange surface membrane lung..

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Hematologic Evaluation of Intraoperative Autologous Blood Collection and Allogeneic Transfusion in Cardiac Surgery

Abstract Background Acute normovolemic hemodilution is recommended as a technique to reduce allogeneic red blood cell (RBC) transfusions in cardiac surgery, but its efficacy to reduce non‐RBC transfusion has not..

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In vitro head-to-head comparison of anticoagulation properties of two heparin brands in a human blood miniature mock loop

Abstract OBJECTIVES The first aim was the development of a human blood miniature mock-loop system consisting of 2 identical extracorporeal circuits, which enable systematic head-to-head comparisons of test substances. In..

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Left Ventricular Unloading During Veno-Arterial ECMO: A Simulation Study

Abstract Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is widely used in cardiogenic shock. It provides systemic perfusion, but left ventricular (LV) unloading is suboptimal. Using a closed-loop, real-time computer model..

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Impaired right ventricular ejection fraction after cardiac surgery is associated with a complicated ICU stay

Abstract Background Right ventricular (RV) dysfunction is a known risk factor for increased mortality in cardiac surgery. However, the association between RV performance and ICU morbidity is largely unknown. Methods..

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People, systems and safety: resilience and excellence in healthcare practice

Abstract This article outlines recent developments in safety science. It describes the progression of three ‘ages’ of safety, namely the ‘age of technology’, the ‘age of human factors’ and the..

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The cardiopulmonary bypass and cancer dissemination puzzle

Abstract Early cancer diagnosis, new therapies that increased survival of patients, besides the increasingly elderly population are some factors would be associated with possible cancer dissemination in patients under cardiopulmonary..

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Incidence and risk factors for potentially suboptimal serum concentrations of vancomycin during cardiac surgery

Abstract AIM To investigate the incidence and risk factors for vancomycin concentrations less than 10 mg/L during cardiac surgery. METHODS In this prospective study, patients undergoing cardiac surgery received a..

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Q-PULS, a new quasi-physiological pulsatile extracorporeal model to simulate heart function

Abstract OBJECTIVES The invention of new surgical procedures requires testing at different stages including animal models. To facilitate this process, we have developed a computer-controlled extracorporeal circulation system for testing..

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Comparison of temporary ventricular assist devices and extracorporeal life support in post-cardiotomy cardiogenic shock

Abstract OBJECTIVES Post-cardiotomy cardiogenic shock (PCCS) results in substantial morbidity and mortality, whereas refractory cases require mechanical circulatory support (MCS). The aim of the study was to compare extracorporeal membrane..

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Novel method for estimating the total blood volume: the importance of adjustment using the ideal body weight and age for…

Abstract OBJECTIVES Although total blood volume (TBV) is central to the estimation of the haemodilution rate during cardiopulmonary bypass (CPB), conventional formulas lack sufficient accuracy. The aim of this study..

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Transient acute kidney injury after cardiac surgery does not independently affect postoperative outcomes

Abstract Background The objective of this study was to assess the incidence of in‐hospital acute kidney injury (AKI) after cardiac surgery by comparing preoperative baseline renal function with renal function..

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Protecting the Value of Medical Science in the Age of Social Media and “Fake News”

Abstract New threats to effective scientific communication make it more difficult to separate science from science fiction. Patients can be harmed by misinformation or by misplaced trust; for example, patients..

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Anaphylaxis to intravenous gelatin‐based solutions: a case series examining clinical features and severity

Abstract The proportion of patients receiving intravenous gelatin‐based colloids has increased in the last decade due to safety concerns about starch‐based products. Recent research suggests hypersensitivity reactions to intravenous gelatin‐based..

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Workplace bullying and workplace violence as risk factors for cardiovascular disease: a multi-cohort study

Abstract Aims To assess the associations between bullying and violence at work and cardiovascular disease (CVD). Methods and results Participants were 79 201 working men and women, aged 18–65 years and free..

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Audit of transfusion of blood products in paediatric congenital heart surgery on cardiopulmonary bypass

Abstract Background: Cardiac surgery is associated with peri-operative bleeding, which may result in the need for blood transfusion, particularly in paediatric congenital cardiac surgery on cardiopulmonary bypass (CPB). There is..

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Effects of cardiopulmonary bypass on the disposition of cefazolin in patients undergoing cardiothoracic surgery

Abstract The aim of the study was to evaluate the disposition of plasma unbound cefazolin in patients undergoing cardiothoracic surgery with cardiopulmonary bypass (CPB). Adult patients undergoing cardiothoracic surgery with..

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Anything Goes? High Time for Smart Blood Volume Monitors

Abstract In this issue of the ASAIO Journal, Keane et al. present the results of their exploratory study on the combined use of whole body bioimpedance (WBB) and relative blood volume (RBV) monitoring..

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Fish Oil and Perioperative Bleeding

Abstract Background Fish oil is among the most common natural supplements for treatment of hypertriglyceridemia or prevention of cardiovascular disease. However, concerns about theoretical bleeding risk have led to recommendations..

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Importance of safety climate, teamwork climate and demographics: understanding nurses, allied health professionals and clerical staff perceptions of patient safety

Abstract Background  There is growing evidence regarding the importance of contextual factors for patient/staff outcomes and the likelihood of successfully implementing safety improvement interventions such as checklists; however, certain literature..

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Scientific Misconduct and Medical Journals

According to the US Department of Health and Human Services, “Research misconduct means fabrication, falsification, or plagiarism in proposing, performing, or reviewing research, or in reporting research results.” Other important irregularities..

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Positive impact of retrograde autologous priming in adult patients undergoing cardiac surgery: a randomized clinical trial

Abstract Background Adult cardiac surgery with extracorporeal circulation is known to be associated with increased risk of blood transfusion leading to adverse outcomes. Procedures like retrograde autologous priming (RAP) may..

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Is the Cardiopulmonary Bypass Systemic Inflammatory Response Overestimated?

Abstract According to a survey by the University of Ottawa in 2009, we have surpassed the 50 million mark over the total number of scientific articles published since 1665, and..

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Selective visceral perfusion improves renal flow and hepatic function in neonatal aortic arch repair

Abstract OBJECTIVES The aortic arch repair in the neonatal period is a complex procedure with significant morbidity. We define a useful double-perfusion technique and its effect on the function of..

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Does minimally invasive coronary artery bypass improve outcomes compared to off-pump coronary bypass via sternotomy in patients undergoing coronary artery…

Abstract A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was ‘In patients undergoing off-pump coronary artery bypass grafting, for single or..

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Risk Factors for Prolonged Intensive Care Unit Stay After Open Heart Surgery in Adults

Abstract Objective Prolonged intensive care unit (ICU) stay prevents the use of ICU equipment by other patients and increases hospital cost. This retrospective study aimed to investigate the risk factors..

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