Perfusfind S.L.
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A Risky Proposition: Blood Transfusion and the Risk of Surgical Site Infections

Abstract In our perpetually evolving pursuit to optimize the risk-benefit profile of perioperative interventions, the decision to administer allogeneic blood products is fraught with extraordinarily conflicting goals. This infographic summarizes..

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Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery

Abstract BACKGROUND:  Declining platelet counts may reveal platelet activation and aggregation in a postoperative prothrombotic state. Therefore, we hypothesized that nadir platelet counts after on-pump coronary artery bypass grafting (CABG)..

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Cardiopulmonary Resuscitation in Adults and Children With Mechanical Circulatory Support: A Scientific Statement From the American Heart Association

Abstract Cardiac arrest in patients on mechanical support is a new phenomenon brought about by the increased use of this therapy in patients with end-stage heart failure. This American Heart..

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Effect of Levosimendan on Low Cardiac Output Syndrome in Patients With Low Ejection Fraction Undergoing Coronary Artery Bypass Grafting With…

Abstract Importance   Low cardiac output syndrome after cardiac surgery is associated with high morbidity and mortality in patients with impaired left ventricular function. Objective   To assess the ability of preoperative..

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Right atrial pressure and venous return during cardiopulmonary bypass

Abstract The relevance of right atrial pressure (RAP) as the backpressure for venous return (QVR) and mean systemic filling pressure as upstream pressure is controversial during dynamic changes of circulation...

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Insidious Risk of Severe Mycobacterium chimaera Infection in Cardiac Surgery Patients

Abstract Background. An urgent UK investigation was launched to assess risk of invasive Mycobacterium chimaera infection in cardiothoracic surgery and a possible association with cardiopulmonary bypass heater-cooler units following alerts in Switzerland..

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Renal haemodynamics and oxygenation during and after cardiac surgery and cardiopulmonary bypass

Abstract Acute kidney injury (AKI) is a common complication following cardiac surgery performed on cardiopulmonary bypass (CPB) and has important implications for prognosis. The aetiology of cardiac surgery‐associated AKI is..

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Novel Rotational Speed Modulation System Used With Venoarterial Extracorporeal Membrane Oxygenation

Abstract Background Femoral venoarterial  (VA-ECMO) is widely used to maintain blood flow in patients with . However, retrograde blood flow increases left ventricular (LV) afterload during femoral VA-ECMO. Additional support by means..

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Predictable capability control scheme for oxygen-exchange blood flow regulation in an extracorporeal membrane oxygenation system

Abstract Extracorporeal membrane oxygenation system is used for rescue treatment strategies for temporary cardiopulmonary function support to facilitate adequately oxygenated blood to return into the systemic and pulmonary circulation systems...

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Bleeding and thrombosis associated with ventricular assist device therapy

Abstract Over the past decade, continuous-flow rotary pumps have dramatically improved survival for patients with advanced . Bleeding and thrombosis, however, continue to be the Achilles heel of  (LVAD) therapy. There is..

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2016 survey about temperature management during extracorporeal circulation in China

Abstract Objective: In order to assess the current status of temperature management during cardiopulmonary bypass (CPB) in China and, thereby, implement standardized management protocols, the authors carried out a national..

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New Technology Mimics Physiologic Pulsatile Flow During Cardiopulmonary Bypass

Abstract The VentriFlo True Pulse Pump (Design Mentor, Inc., Pelham, NH, USA) is the first blood pump designed to mimic human arterial waveforms in a standard oxygenation circuit. Our aim was..

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Cerebral Microhemorrhage: A Frequent Magnetic Resonance Imaging Finding in Pediatric Patients after Cardiopulmonary Bypass

Abstract Objectives: This study was undertaken to estimate the incidence and burden of cerebral microhemorrhage (CM) in patients with heart disease who underwent cardiopulmonary bypass (CPB), as detected on susceptibility-weighted..

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Risk factors for delirium after cardiac surgery: a historical cohort study outlining the influence of cardiopulmonary bypass

Abstract Purpose Cardiopulmonary bypass (CPB) induces a significant inflammatory response that may increase the risk for delirium. We hypothesized that exposure to CPB during coronary artery bypass grafting (CABG) surgery..

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A retrospective comparison of inhaled milrinone and iloprost in post-bypass pulmonary hypertension

Abstract During cardiac operations, weaning from cardiopulmonary bypass (CPB) may prove challenging as a result of superimposed acute right ventricular dysfunction in the setting of elevated pulmonary vascular resistance (PVR)...

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Prophylactic Fibrinogen Decreases Postoperative Bleeding but Not Acute Kidney Injury in Patients Undergoing Heart Transplantation

Abstract The present study is the premier clinical attempt to scrutinize the practicability of prophylactic fibrinogen infusion in patients undergoing heart transplantation (HT). A total of 67 consecutive patients who..

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Haem is associated with thrombosis in neonates and infants undergoing cardiac surgery for congenital heart disease

Abstract Background Haem levels are associated with thrombosis in a variety of diseases, as well as being a contributing cause of thrombotic events in animal models. Materials and Methods We..

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Assessing the depth of isoflurane anaesthesia during cardiopulmonary bypass

Abstract Introduction: Bispectral index (BIS) and monitoring of end-tidal concentration may be associated with a reduction in the incidence of awareness during volatile-based general anaesthesia. An analogue of end-tidal concentration..

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Influence of high-flow modified ultrafiltration on brain oxygenation and perfusion during surgery for children with ventricular septal defects: a pilot…

Abstract Background: Modified ultrafiltration (MUF) can be performed in infants with ventricular septal defects (VSDs) after cardiopulmonary bypass (CPB) to reduce haemodilution and its potential adverse effects. High-flow MUF might..

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Prevalence and Overtesting of True Heparin-Induced Thrombocytopenia in a 591-Bed Tertiary Care, Teaching Hospital

Abstract Heparin-induced thrombocytopenia type II (HIT) is a rare but potentially fatal antibody-mediated reaction to all forms of heparin (unfractionated heparin, low-molecular weight heparin, heparin flushes, and heparin-coated catheters), which..

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Normothermic Cardiopulmonary Bypass in Patient With Waldenström’s Macroglobulinemia and Cryoglobulinemia: A Case Report

Abstract Waldenström’s macroglobulinemia (WM) manifests as hyperviscosity syndrome. Cryoglobulinemia, which may increase blood viscosity or induce thrombosis in association with decreased body temperature, can occur in combination with WM. We..

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Brain-Dead Donors on Extracorporeal Membrane Oxygenation

Abstract Objectives:  To describe donors after brain death with ongoing extracorporeal membrane oxygenation and to analyze the outcome of organs transplanted from these donors. Design:  Retrospective analysis of the national..

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Pediatric Extracorporeal Membrane Oxygenation

Extracorporeal life support (ECLS), commonly referred to as extracorporeal membrane oxygenation (ECMO), is a modified form of cardiopulmonary bypass. Venous blood is drained from the patient and advanced to a..

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Empirical Vancomycin Dosing in Pediatric Patients with Congenital Heart Disease and the Impact of Cardiopulmonary Bypass on Trough Concentrations

Abstract Objectives To determine the optimal vancomycin dosing regimen to achieve empirical goal trough concentrations in pediatric patients with congenital heart disease and to examine the impact of cardiopulmonary bypass..

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Practice meta-environment of the cardiovascular perfusionist

Abstract Though historically the development of cardiovascular perfusion grew out of the need for cardiopulmonary bypass, the application of technologies of extracorporeal support has more recently expanded beyond the traditional..

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Differentiating between cold agglutinins and rouleaux: a case series of seven patients

Abstract We present a case series of seven patients with suspected cold agglutinin antibodies, discovered after initiation of bypass. Laboratory analysis of blood samples intraoperatively determined the cause of the..

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Operative strategies to reduce cerebral embolic events during on- and off-pump coronary artery bypass surgery: A stratified, prospective randomized trial

Abstract Objective To determine the impact of different  strategies on the incidence of cerebral embolic events during  (CABG). Methods Between 2012 and 2015, 142 patients with low-grade  (epiaortic ultrasound grade I/II) undergoing primary..

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The neurologic protection of unilateral versus bilateral antegrade cerebral perfusion in aortic arch surgery with deep hypothermic circulatory arrest: A…

Abstract Backgroud Unilateral and bilateral antegrade  (ACP) are recognized methods of cerebral protection in . However, the adequacy of cerebral protection in aortic arch surgery with  is controversial. In this study, we compared..

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