Perfusfind S.L.
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On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death

Abstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant..

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Assisted artificial intelligence in medical writing: a primer for humans

Abstract Assisted artificial intelligence (A-AI) has rapidly become a gold standard approach for conducting data analysis and medical writing []. From executing complex statistical tasks to extracting relevant information and..

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Technique of Intra-Aortic Balloon Pump Insertion Through Axillary Artery Over a Chimney Graft

Abstract Intra-aortic balloon pump (IABP), which augments coronary blood flow and reduces cardiac afterload, is the most widely used temporary mechanical circulatory support (TMCS) device. It has been used in..

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Is hyperoxia in early pediatric veno-veno extracorporeal life support associated with mortality?

Abstract Background: Data is limited regarding the effects of supraphysiologic blood oxygen tension (hyperoxia) in patients requiring extracorporeal life support (ECLS). We sought to evaluate the association between hyperoxia and..

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Time-dose response of oxygen delivery during cardiopulmonary bypass in mitral valve surgery: does surgical approach matter?

Abstract Introduction Increased time-dose-response (TDR) of suboptimal oxygen delivery (DO2) during cardiopulmonary bypass (CPB) has been associated with increased postoperative complications. The impact of surgical approach - minimally invasive vs...

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Randomized Trials in Cardiac Surgery: Why and How

Abstract OBJECTIVES Randomized clinical trials (RCTs) are the gold standard for comparative effectiveness. However, they face unique challenges in cardiac surgery. The objective of this work is to summarize the..

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Efficacy of hemadsorption combining with cardiopulmonary bypass used in patients with acute type A aortic dissection

Abstract Background It is hypothesized that combining HA380 with cardiopulmonary bypass (CPB) in acute type A aortic dissection (ATAAD) surgery could reduce the inflammatory response induced by CPB and subsequently..

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Unilateral Versus Bilateral Antegrade Cerebral Perfusion in Aortic Arch Surgery: Systematic Review and Meta-Analysis of Randomised Controlled Trials and Propensity-Matched…

Abstract Background Selective antegrade cerebral perfusion, via unilateral antegrade cerebral perfusion (uACP) or bilateral antegrade cerebral perfusion (bACP) approaches, is used in aortic arch surgery to protect the brain during..

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Work in Europe: schools and Board

We are getting a lot of questions about working in Europe as a Perfusionist. Each country has its own regulations, its perfusion qualification, but we always say that a great..

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Mitochondrial Dysfunction in Cardiac Surgery

Abstract The human heart has one of highest metabolic requirements in the body: even in a resting physiologic state it must work to circulate approximately 5 L/min to 8 L/min..

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Activated Clotting Time Measured by Hemochron Signature Elite in Adult Cardiac Surgery: Implications for Clinical Practice

Abstract Objectives To assess concordance between Hemochron Response (ACTr) and the three-activator device Hemochron Signature Elite (ACTe) in adult cardiac surgery patients. To evaluate the correlation between ACTe and anti-Xa..

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Mortality and Complications in Hybrid Extracorporeal Membrane Oxygenation: A Meta-Analysis of Initial Use Versus Transition

Abstract Hybrid extracorporeal membrane oxygenation (ECMO), containing additional ECMO cannulations in addition to conventional ECMO, is increasingly used for the treatment of serious cardiopulmonary conditions. Patients initiating non-hybrid ECMO may..

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Pulsatile Physiological Control of Blood Pump-Cardiovascular System Based on Feedforward Compensation

Abstract Rotary Blood Pump (RBP) is a commonly used ventricular assist device. However, the constant speed operation of the blood pump leads to a reduction of blood flow pulsatility, which..

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Crisis management in the operating room: A systematic review of simulation training to develop non-technical skills

Abstract Aims Crises in the operating room, often resulting from human factors, endangers patient safety. Simulation-based training to develop non-technical skills shows promise in managing these crises. This review examines..

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Critical hematological parameters in bleeding during extracorporeal membrane oxygenation support

Abstract Bleeding complications are frequently observed in patients undergoing extracorporeal membrane oxygenation and are associated with increased mortality. Due to the complex mechanisms, managing bleeding during ECMO remains a challenge...

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Comprehensive secondary analysis of thrombotic events in pediatric patients receiving extracorporeal membrane oxygenation: A prospective cohort study

Abstract Introduction This study aims to describe laboratory and clinical factors associated with thrombotic events during prolonged pediatric extracorporeal membrane oxygenation. Methods A secondary analysis of a multi-center prospective study..

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Veno-Arterial Extracorporeal Membrane Oxygenation in Cardiotoxic Drug-Induced Cardiogenic Shock: A Systematic Narrative Review

Abstract Background: Severe poisoning can lead to catastrophic cardiovascular collapse, often progressing to multiorgan failure and death. While intensive supportive care and pharmacological intervention remain the cornerstone of management, cases of..

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Transcutaneous Monitoring of Carbon Dioxide to Optimize Ventilator Weaning in At-Risk Adults After Cardiopulmonary Bypass

Abstract Background  Cardiopulmonary bypass use during surgery disrupts microcirculation, which can contribute to lung injury, particularly in patients with pulmonary comorbidities. Continuous transcutaneous carbon dioxide (CO2) monitoring assists clinicians to..

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Multidisciplinary, evidence-based, patient-centred perioperative patient safety recommendations: a European consensus study

Abstract Background Surgery-related adverse events are among the most common adverse events in-hospital. However, no comprehensive, multidisciplinary perioperative guidelines exist at the European level. The aim of this study is..

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Cycle ergometers in extracorporeal membrane oxygenation patient rehabilitation: A scoping review

Abstract Introduction The aim of this scoping review was to determine what evidence is available regarding the use of the cycle ergometer in the rehabilitation of adult patients undergoing extracorporeal..

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Circulating amino acid levels in infants undergoing congenital heart disease surgery: near global decrease following cardiopulmonary bypass and impact of…

Abstract Introduction Amino acids (AAs) serve diverse roles, and insufficient delivery is associated with worse outcomes in ill patients. In the case of congenital heart disease (CHD) surgery with cardiopulmonary..

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Human judgment error in the intensive care unit: a perspective on bias and noise

Abstract Background In the Intensive Care Unit (ICU), clinicians frequently make complex, high-stakes judgments, where inaccuracies can profoundly affect patient outcomes. This perspective examines human judgment error in ICU settings,..

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Near-Infrared Spectroscopy for Preventing Limb Ischemia in Extracorporeal Membrane Oxygenation

Abstract Background Limb ischemia is a serious complication of venoarterial (VA) extracorporeal membrane oxygenation (ECMO), potentially resulting in amputation, rhabdomyolysis, or death. This study aimed to evaluate the effectiveness of..

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Intravenous amino acids for renal protection in patients receiving temporary mechanical circulatory support: a secondary subgroup analysis of the PROTECTION…

Abstract OBJECTIVES In cardiac surgery patients, acute kidney injury (AKI) frequently occurs in the setting of haemodynamic instability and treatment with temporary mechanical circulatory support (tMCS). Recent evidence suggests amino..

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Total thyroidectomy performed under general anesthesia with venovenous extracorporeal membrane oxygenation during a thyroid storm: a case report

Abstract Thyroid storm (TS) is an endocrine emergency requiring aggressive medical management. In severe cases, hemodynamic instability may necessitate extracorporeal membrane oxygenation (ECMO) support as a bridge to definitive surgical..

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Additional Carbon Dioxide Removal by Oxygenated Dialysis Fluid: Insights for the Development of a Novel Lung and Kidney Assist Device

Abstract RenOx, a novel artificial lung and kidney assist device, combines gas exchange and dialysis fibers for integrated respiratory and renal support, with dialysis fibers intended for toxin clearance and..

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Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off

Abstract Extracorporeal membrane oxygenation (ECMO) is widely recognized as a life-saving measure. The use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) is on the rise, serving as an effective mechanical..

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The predictive power of hemodynamic data on postoperative neurocognitive impairment: a logistic regression and random forest approach

Abstract This study assesses hemodynamic data and parameter combinations in predicting neurocognitive impairment post-cardiopulmonary bypass graft (CABG) using logistic regression and random forest algorithms. 28 patients underwent the Montreal Cognitive..

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The Effect of Sevoflurane Versus Total Intravenous Anesthesia on Intraocular Pressure in Patients Undergoing Coronary Artery Bypass Graft Surgery with…

Abstract Background and Objectives: The aim of this study was to compare the effects of sevoflurane-based anesthesia and propofol-based total intravenous anesthesia (TIVA) on intraocular pressure (IOP) during coronary artery..

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Visualizing Flow Dynamics in a Human Aorta During Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Treatment Through Particle Image Velocimetry Study

Abstract Purpose To build a mock circulatory loop to simulate veno-arterial extracorporeal membrane oxygenation (V-A ECMO) haemodynamics using a patient-specific silicone aortic phantom and compare the flow dynamics for continuous..

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