Perfusfind S.L.

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a commonly used in refractory cardiogenic shock (CS) but may exacerbate left ventricular (LV) loading conditions and impair cardiac energetics. Adjunctive LV..

Perfusfind S.L.

Abstract Background Extracorporeal circulation (ECC) is an essential operation in many cardiac surgeries, but contact between blood and connecting tubes can activate inflammatory factors and adversely affect complement. Previous studies..

Perfusfind S.L.

Abstract In extracorporeal therapies such as cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO), the transport of blood through artificial circulation frequently results in the rupture of erythrocytes, releasing hemoglobin..

Perfusfind S.L.

Abstract The Extracorporeal Life Support Organization (ELSO) has progressively transformed its guideline framework to meet the increasing clinical, scientific, and operational demands of modern extracorporeal life support. Since its establishment..

Perfusfind S.L.

Abstract Background Takotsubo cardiomyopathy (TTC) is an episode of transient left ventricular (LV) dysfunction affecting 2.1% of patients with suspected acute ST-segment elevation myocardial infarction. Case Summary A 61-year-old woman..

Perfusfind S.L.

Abstract As adult programs of newer anthrombotic agents, such as those directed against FXIa, are underway, there is both a pressing need and a great opportunity to optimize the design,..

Perfusfind S.L.

Abstract Objectives To determine whether preoperative platelet (PLT) count independently predicts in-hospital mortality in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO). Design Secondary analysis of a prospectively maintained institutional registry...

Perfusfind S.L.

Abstract Background Patients undergoing cardiac surgery are at high risk of severe immediate postoperative complications. Predicting immediate postoperative adverse events remains challenging owing to the complex and nonlinear interplay of..

Perfusfind S.L.

Abstract It seems logical to divide the macrocirculation into systemic and pulmonary circulation, but it is rare in clinical practice to further subdivide microcirculation into systemic and pulmonary microcirculation. Both..

Perfusfind S.L.

Abstract Floating thrombi of the aortic arch constitute rare yet highly consequential lesions with high embolic risk for which optimal management remains debated. Conventional surgical management typically requires deep hypothermic..

Perfusfind S.L.

Abstract Background Lung-protective ventilation in acute respiratory distress syndrome (ARDS) can lead to hypercapnia, an independent risk factor for increased mortality. Extracorporeal CO2 removal (ECCO2R) enables further reduction of ventilator intensity,..

Perfusfind S.L.

Abstract Objective This study aimed to investigate the association of continuous renal replacement therapy (CRRT) use with the prognosis of patients undergoing extracorporeal membrane oxygenation (ECMO) and to explore its..

Perfusfind S.L.

Abstract Objectives Previous studies have shown that Buckberg microplegia reduces the need for intraoperative blood transfusion by minimizing hemodilution. However, this approach has been largely understudied in the context of..

Perfusfind S.L.

Abstract Objectives Whether patients with kidney failure who undergo cardiac surgery have a survival advantage with previous kidney transplantation is unclear. This study evaluated long-term outcomes after cardiac surgery for..

Perfusfind S.L.

Abstract Background Acute kidney injury (AKI) is frequent in patients supported with venoarterial extracorporeal membrane oxygenation (VA-ECMO), largely due to the severity of cardiogenic shock and multiorgan failure. Renal replacement..

Perfusfind S.L.

Abstract Background Nearly 500,000 open-heart operations are performed annually in the United States, with complications such as postcardiotomy cardiogenic shock (PCCS) occurring in 2–9% of cases. Extracorporeal membrane oxygenation (ECMO)..

Perfusfind S.L.

Abstract Background:  Static or averaged electroencephalography (EEG) metrics may fail to capture dynamic cerebral changes during surgery. We assessed the EEG features during aortic arch surgery with cardiopulmonary bypass (CPB)..

Perfusfind S.L.

Abstract Objective Postoperative days alive and out of hospital within 30 days (DAH-30) is a validated, patient-centered metric reflecting the quality of care and recovery after surgery. This study aimed..

Perfusfind S.L.

Abstract Background Cardiogenic shock (CS) is a severe complication of ST-elevation myocardial infarction (STEMI) with high mortality despite advancements in treatment. Mechanical circulatory support (MCS) devices, such as extracorporeal membrane..

Perfusfind S.L.

Abstract Lactate has traditionally been framed as a by-product of anaerobic metabolism and a surrogate for tissue hypoxia. Contemporary physiology recasts lactate as a central fuel, shuttle, and signaling molecule,..

Perfusfind S.L.

Abstract Blood clots are pivotal for haemostasis and regeneration, but they are mechanically weak and form slowly, posing risks for life-threatening haemorrhage and limiting broader applications,,. These limitations are attributed..

Perfusfind S.L.

Abstract Objective Vasoplegia and endothelial dysfunction are well-known complications of cardioplegia and cardiopulmonary bypass (CP/CPB). Our lab has previously shown that endothelial adherens junction impairment is driven by vascular endothelial..

Perfusfind S.L.

Abstract BACKGROUND:  Penetrating cardiac injuries caused by firearms are associated with extremely high prehospital and early in-hospital mortality. During wartime, civilian cardiac surgery centers are increasingly involved in the management..

Perfusfind S.L.

Abstract Background Patients supported with extracorporeal membrane oxygenation (ECMO) are susceptible to healthcare-associated infections (HAIs), which may worsen outcomes. However, epidemiological data from Latin American centres remain scarce. Methods We..

Perfusfind S.L.

Abstract In cardiogenic shock (CS), blood lactate concentration is routinely used to assess shock severity and guide clinical decisions. However, lactate interpretation is often oversimplified, leading to confusion between disease..

Perfusfind S.L.

Abstract Congenital heart disease often requires early surgical intervention. Cardiopulmonary bypass (CPB) is a standard procedure, but infants undergoing CPB show an increased risk of postoperative white matter injury. These..

Perfusfind S.L.

Abstract Although extracorporeal membrane oxygenation (ECMO) has emerged as a pivotal temporary extracorporeal life support in critically ill patients, it is associated with a high risk of mortality. Establishing a..

Perfusfind S.L.

Abstract Objective To characterize relationships between social determinants of health (SDoH) and mortality among infants receiving extracorporeal membrane oxygenation (ECMO). Study design Retrospectively, we identified infants born >34weeks gestation and..

Perfusfind S.L.

Abstract We present the first characterization of multiple organ dysfunction (OD) patterns and their associations with in-hospital mortality for children on extracorporeal membrane oxygenation (ECMO). We retrospectively assessed OD for..

Perfusfind S.L.

Abstract Acute kidney injury (AKI) and fluid accumulation (FA) are common during extracorporeal membrane oxygenation (ECMO) support and are associated with increased morbidity and mortality. Despite their clinical importance, contemporary..