Abstract Objectives Minimally invasive mitral valve surgery (MIV-MVS) continues to evolve through refinements in surgical technique and perioperative management. This study evaluated the association between arterial cannulation strategy and perioperative..
Read MoreAbstract Objectives We investigated the effects of the combined use of preoperatively separated autologous red blood cells, plasma, and fibrin sealant on reducing allogeneic blood transfusion during valve-sparing root replacement..
Read MoreAbstract Acute limb ischemia (ALI) remains one of the most common complications of peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Across heterogeneous cohorts, reported ALI rates vary widely (≈8–30% and..
Read MoreAbstract Peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) and minimally invasive cardiac surgery often require femoral arterial cannulation, wherein lower limb ischemia remains a major complication. Although introducer sheaths with side..
Read MoreAbstract Background Cerebral hemodynamic disturbances are common in neonates receiving extracorporeal membrane oxygenation (ECMO), yet systematic data describing changes in cerebral hemodynamics during ECMO support remain limited. This study was..
Read MoreAbstract Introduction Direct thrombin inhibitors (DTIs) are an alternative to unfractionated heparin during pediatric ECMO. We aimed to describe their use and limitations across Europe. Methods Fifty-two pediatric EuroELSO centers..
Read MoreAbstract Cardiac surgery-associated acute kidney injury (CS-AKI) is reported in 20–30% of patients undergoing cardiac surgery, leading to poor outcomes and increased healthcare costs. Because the pathophysiology of CS-AKI remains..
Read MoreAbstract In the accompanying article in this issue, we reported the survival of a 4 month old infant with severe necrotizing pneumonia due to respiratory syncytial virus (RSV) and methicillin-resistant Staphylococcus..
Read MoreAbstract Background We aimed to clarify the changes in sevoflurane blood concentrations in cardiovascular surgeries with cardiopulmonary bypass (CPB) under mild to moderate hypothermia. Methods In this single-center, prospective observational..
Read MoreAbstract Electrophysiological signals are fundamental to elucidating the functional states and pathological mechanisms of the cardiac and nervous system. Yet, conventional techniques are constrained by inherent trade-offs between high-throughput capabilities,..
Read MoreAbstract Perioperative neurocognitive disorders (PNDs) are frequent and severe complications in older surgical patients, encompassing postoperative delirium, delayed neurocognitive recovery, postoperative neurocognitive disorder, and long-term cognitive impairment. These complications lead..
Read MoreAbstract Background ECMO is indicated for respiratory or cardiopulmonary failure despite high oxygen levels, advanced ventilation, and patient optimization, when persistent hypoxemia/hypercapnia threatens life. Aim Compare characteristics and outcomes of..
Read MoreAbstract Clot-fibrinolysis waveform analysis (CFWA) enables the simultaneous assessment of coagulation and fibrinolytic functions within a short timeframe. We evaluated the effects of commonly used anticoagulants on coagulation–fibrinolysis balance using..
Read MoreAbstract Background While Cell Saver technology effectively reduces red blood cell transfusion in the perioperative setting, its impact on the need for pro-hemostatic factors remains unclear. The use of Cell..
Read MoreAbstract Objectives: Pediatric in-hospital cardiac arrest (IHCA) events leading to extracorporeal cardiopulmonary resuscitation (E-CPR) most often occur in the ICU in cardiac patients. Since there is little information about using..
Read MoreAbstract Carbon monoxide (CO) poisoning is a leading cause of toxic exposure-related morbidity and mortality worldwide. Although hyperbaric oxygen therapy increases CO elimination, its clinical use is limited by accessibility,..
Read MoreAbstract Intraoperative hypotension (IOH) has traditionally been regarded as a transient and largely reversible physiological disturbance inherent to the administration of general and regional anaesthesia. However, contemporary perioperative outcomes research..
Read MoreAbstract Objectives: To evaluate the cost-effectiveness of implementing an extracorporeal cardiopulmonary resuscitation (ECPR) strategy for refractory out-of-hospital cardiac arrest (OHCA) compared with current practice in Singapore, where it is not..
Read MoreAbstract The oXiris membrane represents a notable advance in continuous renal replacement therapy for critically ill patients with severe infection, sepsis, and other conditions characterized by immune dysregulation. Built on..
Read MoreAbstract Postoperative pathophysiology and impact from cardiopulmonary bypass The PCS population is unique due to patients’ exposure to cardiopulmonary bypass (CPB) and temporary cardiac arrest, which are associated with cytokine..
Read MoreAbstract Maintenance of tissue oxygenation in patients having surgery is important as tissue hypoxia is a major determinant of organ failure. Tissue oxygenation follows a stepwise physiological pathway involving the..
Read MoreAbstract For pregnant patients with severe coronavirus disease 2019 (COVID-19) requiring veno-venous (V-V) extracorporeal membrane oxygenation (ECMO), the ideal timing of delivery is uncertain, particularly when complicated by cardiogenic shock...
Read MoreAbstract Neurological injury remains a major contributor to morbidity, mortality, and long-term cognitive decline in patients undergoing cardiac surgery, despite significant advancements in surgical techniques and cardiopulmonary bypass (CPB) technology...
Read MoreAbstract Clinical Criteria and Assessment (Hypotension, Hypoperfusion, Rising Lactate, and Escalating Vasopressors) Profound hypotension, ongoing CS despite optimal medical treatment, escalating vasopressor requirements, rapidly deteriorating cardiac function, worsening lactic acidosis,..
Read MoreAbstract Background: The aim of this study was to investigate the efficacy and safety of cell salvage (CS) use in cardiac reoperations and to conduct a cost analysis considering the Turkish..
Read MoreAbstract Introduction Critically ill ECMO patients face high bleeding risks from anticoagulation and other factors. Although viscoelastic tests, like ROTEM, are widely used to assess hemostasis, evidence for their superiority..
Read MoreAbstract Background Cardiac arrest in the intensive care unit (ICU-CA) is distinct from other in-hospital cardiac arrests, involving critically ill patients in monitored settings. Its prevalence and outcomes remain unclear...
Read MoreAbstract Purpose The minimal invasive extracorporeal circulation (MiECC) was developed as abiocompatible alternative to conventional cardiopulmonary bypass (cCPB), intending to mitigate haemodilution, lessen the systemic inflammatory response, and enhance organ..
Read MoreAbstract Neonatal fluid management in extracorporeal life support (ECLS) is complex, with the goal of improving outcomes while preventing complications. This study evaluates the impact of early continuous renal replacement..
Read MoreAbstract Postoperative delirium (POD) is a common neurocognitive complication after cardiac surgery in elderly patients and is associated with adverse clinical outcomes. Impaired cerebral autoregulation and reduced cerebrovascular reserve may..
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