Perfusfind S.L.
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Heart Recovery Techniques

Heart Recovery Techniques A. Donor Types 1. DBD (Donation after Brain Death) •Traditional and most common •Heart remains perfused until cross-clamp •Predictable ischemic time 2. DCD (Donation after Circulatory Death)..

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Inflammatory Cytokines as Early Predictors of Weaning Failure From Extracorporeal Life Support

Abstract Background Weaning from extracorporeal life support (ECLS) in patients with refractory shock still remains a complex decision. Despite considerable advances in ECLS management, reliable biomarkers to predict weaning success..

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Ketamine in Cardiac Surgery: A Systematic Review and Meta-Analysis of Effects on Inflammatory Markers and Clinical Outcomes

Abstract Cardiac surgery triggers a systemic inflammatory response, especially when cardiopulmonary bypass (CPB) is used, which may contribute to postoperative complications. Ketamine, an NMDA receptor antagonist, has shown anti-inflammatory potential..

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Evaluation of non-invasive sensors for monitoring core temperature

Abstract We evaluated the accuracy and precision of zero-heat flux (ZHF) and dual sensor (DS) non-invasive temperature probes in intensive care unit (ICU) patients undergoing hypothermic temperature control, hypothesizing that..

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Evaluation of Cardiac Output Estimation with Veno-Venous Extracorporeal membrane Oxygenation Support: in vitro study

Abstract Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is used to treat refractory lung failure, a condition that often results in right ventricular dysfunction, which can exacerbate both morbidity and mortality...

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Extracorporeal Membrane Oxygenation for Calcium Channel Blocker Intoxication: A Multicenter Retrospective Registry Review

Abstract Calcium channel blocker (CCB) toxicity can lead to cardiogenic shock and circulatory collapse. Extracorporeal membrane oxygenation (ECMO) has been used as salvage therapy when conventional treatments fail, but outcomes..

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Extracellular vesicles in cardiac surgery: unlocking new frontiers in cardioprotection and patient outcomes

Abstract Cardiac surgery, while life-saving, induces profound physiological stress due to ischemia–reperfusion injury (IRI), systemic inflammation, and endothelial dysfunction, particularly in procedures involving cardiopulmonary bypass. In this complex setting, extracellular..

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Diabetes Mellitus and Cardiopulmonary Bypass (CPB): Pathophysiological Mechanisms Related to Inflammation and Cardiovascular Disease

Abstract Type 2 Diabetes Mellitus (T2DM) is a chronic disease caused by the resistance of tissues to the actions of insulin as well as the progressive failure to produce adequate..

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Bleeding Complications from Chest Tube Treatment in Patients on Extracorporeal Membrane Oxygenation Support

Abstract Objectives Bleeding is a common complication of extracorporeal membrane oxygenation (ECMO) support. While chest tube treatment is infrequently linked to bleeding in non-ECMO patients, several reports suggest a markedly..

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Oxidative Stress and NLRP3 Inflammasome as Markers of Cardiac Injury Following Cardiopulmonary Bypass: Potential Implications for Patients with Preoperative Heart…

Abstract Cardiopulmonary bypass (CPB) can lead to cardiac damage due to oxidative stress (OS) and inflammation in heart failure (HF). We tested the hypothesis that preoperative HF patients with reduced..

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Non-invasive vs biological blood determination of haemoglobinemia for perioperative management: a systematic review with meta-analysis

Abstract Introduction Haemoglobin measurement is an essential parameter for quantifying anaemia and often used for guiding transfusion decisions. Conventional methods require blood sampling and are invasive. Results are intermittent, discontinuous..

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Crossing the line: blood transfusion thresholds in ECMO

Abstract In the high-stakes realm of extracorporeal membrane oxygenation (ECMO), every decision can have profound consequences—from initiation to termination. Management controversies persist throughout the entire course. Beyond patient selection, timing,..

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Impact of Ventilation Discontinuation During Cardiopulmonary Bypass: A Prospective Observational Study

Abstract Background: Discontinuing mechanical ventilation during cardiopulmonary bypass (CPB) is common but may adversely affect postoperative pulmonary function. This study aimed to evaluate the impact of stopping ventilation during CPB..

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Effects of Dexmedetomidine on Outcomes After Cardiac Surgery (DOCS): a randomised double-blind, placebo-controlled trial

Abstract Background Organ dysfunction after cardiac surgery may be reduced by dexmedetomidine. We evaluated whether perioperative dexmedetomidine reduces complications after cardiac surgery with cardiopulmonary bypass. Methods In this randomised, double-blind,..

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Ulinastatin mitigates protamine-induced hypotension during cardiac surgery: A retrospective observational study using propensity score matching

Abstract Although protamine induces cardiotoxicity, ulinastatin has been shown to attenuate protamine-induced cardiotoxicity in rats. However, whether ulinastatin alleviates protamine-induced cardiac depression during cardiac surgery remains unclear. This study aimed..

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From pollution to palpitations: the heart’s silent battle with microplastics

Abstract The pervasive presence of microplastics and nanoplastics (MNPs) in the environment has raised growing concerns regarding their potential health impacts. While research has progressively revealed the toxicological effects of..

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Percutaneous Femoral Arterial Closure Following Decannulation of Venoarterial Extracorporeal Membrane Oxygenation Using the MANTA Vascular Closure Device

Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a life-saving therapy for patients with severe cardiac failure. If patients can be weaned, withdrawal and closure of the large-bore arterial access..

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Stabilizing the Unstable: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database of Children Supported With Extracorporeal…

Abstract Background Children with heart disease and cardiopulmonary failure may be supported with extracorporeal membrane oxygenation (ECMO) for stabilization before cardiac surgery. This study describes their epidemiology and outcomes. Methods..

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Epidemiology, outcomes, and three-year quality of life in patients supported with VV-ECMO for critical COVID-19 infection

Abstract BACKGROUND: This single center study analyzed epidemiology, outcomes, and three-year quality of life (QoL) of critically ill COVID-19 patients requiring a possibly life-saving VV-ECMO. METHODS: Demographics, clinical and technical..

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Development and validation of a prediction model for acute kidney injury following cardiopulmonary bypass surgery

Abstract Background Acute renal impairment following cardiopulmonary bypass (CPB) is a serious perioperative complication with sustained occurrence. Proactive risk assessment and preventive strategies are crucial for enhancing surgical outcomes. Methods..

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Integrating a chatbot into simulation-based perfusion training: A pilot randomized controlled trial

Abstract Purpose Chatbots have enhanced student engagement and learning outcomes in education. Simulation-based training is critical in perfusion education, providing risk-free environments for skill mastery and clinical readiness. This research..

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Delta-P as an early indicator of oxygenator failure: the case for standardized manufacturer reference values

Abstract The evolution of extracorporeal membrane oxygenation (ECMO) has led to an increasing reliance on objective parameters to detect complications early and enhance patient safety. One such parameter is the..

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Prognosis of Immunocompromised Patients With Respiratory Failure Managed With Venovenous Extracorporeal Membrane Oxygenation

Abstract Despite the increasing number of critically ill immunocompromised patients in intensive care unit, the outcome of different types of immunocompromised patients with respiratory failure managed with venovenous extracorporeal membrane..

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Simulation-based activated clotting time targeting for cardiopulmonary bypass in patients with antiphospholipid syndrome: two case reports

Abstract Background Antiphospholipid syndrome (APS) is an autoimmune prothrombotic disorder that is frequently associated with systemic lupus erythematosus (SLE). Cardiac surgery in patients with APS presents unique challenges because activated..

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NeoHeart Europe 2026 - July 9/10

NeoHeart Europe 2026 Bridging Disciplines, Advancing Neonatal Cardiac Care Thursday 9-Friday 10 July 2026  With a pre-conference workshop day on Wednesday 8 July BMA House, London NeoHeart Europe 2026 marks..

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ECMO Conference 2026 - March 25/27

Welcome to Nordic Light on ECLS limited 2026, an ECMO conference in the beautiful area of Stockholm, Sweden on March 25-27, 2026. Here you will enjoy ECMO lectures, seminars, discussions..

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Simulación ECMO Adulto - Abril 11/12

Nueva versión de nuestro curso de Simulación ECMO Adulto. Si trabajas en cuidados críticos, perfusión, enfermería o medicina intensiva, este curso es una oportunidad única: - Contenidos alineados a guías..

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DCD Heart and Lung Explantation With TransMedics OCS Heart Recovery and EVLP Lung Perfusion

I. PRE-PROCUREMENT PREPARATION (DCD CONTEXT)   1. Donor Selection and Planning •Confirm controlled DCD donor (Maastricht Category III). •Review: •Warm ischemic time (WIT) thresholds •Functional warm ischemia (fWIT) •Hemodynamics prior..

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Compliance with ESAIC guidelines for fibrinogen concentrate prescription in cardiac surgery: a multicentre French cohort study

Abstract Background Fibrinogen concentrate may reduce allogeneic blood product transfusion in cardiac surgery patients with bleeding associated with acquired hypofibrinogenemia. The European Society of Anaesthesiology and Intensive Care (ESAIC) has..

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Impeller Position in a Magnetically Levitated Rotodynamic Blood Pump and Its Impact on In-Silico Hemocompatibility

Abstract In magnetically levitated rotodynamic blood pumps (RPBs), the impeller position depends on a balance of electromagnetic and fluid dynamic forces. The aim of this study was to describe the..

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