Tags Archives: thrombus

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Long-term thrombus-free left atrial appendage occlusion via magnetofluids

Abstract Peri-device leak and device-related thrombus remain key challenges of current left atrial appendage occlusion (LAAO) owing to the incompatibility between the solid occluder and the left atrial appendage (LAA). Here..

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Smart Clot: An Automated Point-of-Care Flow Assay for Quantitative Whole-Blood Platelet, Fibrin, and Thrombus Kinetics

Abstract Hemostasis depends on the coordinated interaction between platelets, coagulation factors, endothelium, and shear forces. Current point-of-care (POC) assays evaluate isolated components of haemostasis or operate under nearly static conditions,..

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Multimodal characterization of flow-induced thrombus initiation and growth in extracorporeal membrane oxygenation

Abstract In cases of severe cardiopulmonary failure, extracorporeal membrane oxygenation (ECMO) may be temporarily used as a life-saving support for cardiac and/or lung function. Operating under non-physiological flow conditions, characterized..

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Undetected intracardiac thrombus and subsequent embolism following cardiopulmonary bypass: a case report

Abstract Background Heparin is commonly administered to prevent thrombosis during cardiopulmonary bypass (CPB). However, the development of intracardiac thrombi under CPB has still been reported. Case summary A 79-year-old man..

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Thrombus formation in neonates and early infants undergoing congenital heart surgery

Abstract Objective This study evaluated thrombus formation and its impact on outcomes in neonates and early infants undergoing congenital heart surgery. Methods Neonates and early infants (≤90 days) undergoing congenital..

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New Findings on Pulsatile ECMO: Verification of the Potential to Improve Antithrombogenicity of a Membrane Oxygenator Using Pump-Generated Pulsatile Flow…

Abstract Background Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory and respiratory support. However, thrombus formation in the circuit can lead to hemorrhagic complications, requiring improvements in ECMO anti-thrombogenicity. Few studies..

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Anticoagulate the Circuit, Not the Patient: Nitric Oxide Reduces Thrombus Formation During Extracorporeal Carbon Dioxide Removal

Abstract Solutions to reduce the need for systemic anticoagulation during extracorporeal life support would improve safety and utility. The study objective was to evaluate the safety and efficacy of a..

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Thrombus Migration Resulting From Cessation of Cardiopulmonary Bypass Flow in a Patient With Left Ventricular Thrombus

Introduction Left ventricular (LV) thrombus formation is a known complication associated with acute myocardial infarction and other conditions that impair LV function, carrying a risk for systemic embolization., In this report,..

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Prediction of Thrombus Formation within an Oxygenator via Bioimpedance Analysis

Abstract Established clinical monitoring techniques lack predictive capabilities, emphasizing the need for refinement in MO monitoring towards an early warning system. In this study, an MO was modified by integrating..

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“Ping-pong” in the heart: a case report and literature review

Abstract Background Ball thrombus is rare and life-threatening. The correct diagnosis and timely management are key to improving patient prognosis. Here, we present a case report and literature review of..

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Early Blood Clot Detection Using Forward Scattering Light Measurements Is Not Superior to Delta Pressure Measurements

Abstract The occurrence of thrombus formation within an extracorporeal membrane oxygenator is a common complication during extracorporeal membrane oxygenation therapy and can rapidly result in a life-threatening situation due to..

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Intracannula Thrombus Formation Associated With Dual Lumen ProtekDuo Cannula in Extracorporeal Membrane Oxygenation (ECMO)

Abstract Extracorporeal membrane oxygenation (ECMO) is used in cases of severe respiratory failure refractory to medical management. Use of ECMO is increasing, along with new cannulation strategies including oxygenated right..

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In vitro hemocompatibility screening of a slippery liquid impregnated surface coating for extracorporeal organ support applications

Abstract Introduction: Clot formation, infection, and biofouling are unfortunate but frequent complications associated with the use of blood-contacting medical devices. The challenge of blood-foreign surface interactions is exacerbated during medical..

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Thrombus formation during ECMO: Insights from a detailed histological analysis of thrombus composition

Abstract Objectives Intra-device thrombosis remains one of the most common complications during extracorporeal membrane oxygenation (ECMO). Despite anticoagulation, approximately 35% of patients develop thrombi in the membrane oxygenator, pump heads,..

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Use of CytoSorb in case of operative extraction of the massive right atrium thrombus associated with Hickman catheter in Non-Hodgkin…

This case reports on a 16-year-old male patient (weight 56 kg), who was admitted from the hematology-oncology ward to the Pediatric Intensive Care Unit (PICU) after a clinical deterioration with..

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Novel application of indocyanine green fluorescence imaging for real-time detection of thrombus in a membrane oxygenator

Abstract Extracorporeal membrane oxygenation (ECMO) plays an important role in the coronavirus disease 2019 (COVID-19) pandemic. Management of thrombi in ECMO is generally an important issue; especially in ECMO for..

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Thrombus on mechanical prothesis (pre/post)

    Pierluigi Incarnato,  TFCPC Cardiovascular and Abdominal Techinician Sonographer, Cardiac Physiologist at San Michele Nursing Home (Italy)    

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Intraventricular Conundrum in a SARS-CoV-2–Positive Patient With Elevated Biomarkers of Myocardial Injury

Abstract We present a case of acute myocarditis with left ventricular dysfunction and intracavitary thrombosis in a 55-year-old man with severe acute respiratory syndrome coronavirus 2 infection (coronavirus disease 2019)..

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An introduction to point-of-care testing in extracorporeal circulation and LVADs

Abstract There is a delicate balance between bleeding and clotting in patients on circuits such as ventricular assist devices or extracorporeal membrane oxygenation. Traditional coagulation tests, prothrombin time, activated partial..

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Anticoagulation with VADs and ECMO: walking the tightrope

Abstract The evolution of devices for mechanical circulatory support (MCS), including ventricular assist devices (VADs) for patients with heart failure and extracorporeal membrane oxygenation (ECMO) for patients with acute cardiac..

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Treatment of device thrombus in the HeartWare HVAD: Success and outcomes depend significantly on the initial treatment strategy

Background Pump thrombosis is a major adverse event in patients supported with a left ventricular assist device (LVAD). Treatment approaches include device exchange, lytic therapy, or augmentation of anticoagulation or..

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