Abstract Peri-device leak and device-related thrombus remain key challenges of current left atrial appendage occlusion (LAAO) owing to the incompatibility between the solid occluder and the left atrial appendage (LAA). Here..
Read MoreAbstract Hemostasis depends on the coordinated interaction between platelets, coagulation factors, endothelium, and shear forces. Current point-of-care (POC) assays evaluate isolated components of haemostasis or operate under nearly static conditions,..
Read MoreAbstract In cases of severe cardiopulmonary failure, extracorporeal membrane oxygenation (ECMO) may be temporarily used as a life-saving support for cardiac and/or lung function. Operating under non-physiological flow conditions, characterized..
Read MoreAbstract Background Heparin is commonly administered to prevent thrombosis during cardiopulmonary bypass (CPB). However, the development of intracardiac thrombi under CPB has still been reported. Case summary A 79-year-old man..
Read MoreAbstract Objective This study evaluated thrombus formation and its impact on outcomes in neonates and early infants undergoing congenital heart surgery. Methods Neonates and early infants (≤90 days) undergoing congenital..
Read MoreAbstract Background Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory and respiratory support. However, thrombus formation in the circuit can lead to hemorrhagic complications, requiring improvements in ECMO anti-thrombogenicity. Few studies..
Read MoreAbstract Solutions to reduce the need for systemic anticoagulation during extracorporeal life support would improve safety and utility. The study objective was to evaluate the safety and efficacy of a..
Read MoreIntroduction Left ventricular (LV) thrombus formation is a known complication associated with acute myocardial infarction and other conditions that impair LV function, carrying a risk for systemic embolization., In this report,..
Read MoreAbstract Established clinical monitoring techniques lack predictive capabilities, emphasizing the need for refinement in MO monitoring towards an early warning system. In this study, an MO was modified by integrating..
Read MoreAbstract Background Ball thrombus is rare and life-threatening. The correct diagnosis and timely management are key to improving patient prognosis. Here, we present a case report and literature review of..
Read MoreAbstract The occurrence of thrombus formation within an extracorporeal membrane oxygenator is a common complication during extracorporeal membrane oxygenation therapy and can rapidly result in a life-threatening situation due to..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) is used in cases of severe respiratory failure refractory to medical management. Use of ECMO is increasing, along with new cannulation strategies including oxygenated right..
Read MoreAbstract Introduction: Clot formation, infection, and biofouling are unfortunate but frequent complications associated with the use of blood-contacting medical devices. The challenge of blood-foreign surface interactions is exacerbated during medical..
Read MoreAbstract Objectives Intra-device thrombosis remains one of the most common complications during extracorporeal membrane oxygenation (ECMO). Despite anticoagulation, approximately 35% of patients develop thrombi in the membrane oxygenator, pump heads,..
Read MoreThis case reports on a 16-year-old male patient (weight 56 kg), who was admitted from the hematology-oncology ward to the Pediatric Intensive Care Unit (PICU) after a clinical deterioration with..
Read MoreAbstract Extracorporeal membrane oxygenation (ECMO) plays an important role in the coronavirus disease 2019 (COVID-19) pandemic. Management of thrombi in ECMO is generally an important issue; especially in ECMO for..
Read MorePierluigi Incarnato, TFCPC Cardiovascular and Abdominal Techinician Sonographer, Cardiac Physiologist at San Michele Nursing Home (Italy)
Read MoreAbstract We present a case of acute myocarditis with left ventricular dysfunction and intracavitary thrombosis in a 55-year-old man with severe acute respiratory syndrome coronavirus 2 infection (coronavirus disease 2019)..
Read MoreAbstract There is a delicate balance between bleeding and clotting in patients on circuits such as ventricular assist devices or extracorporeal membrane oxygenation. Traditional coagulation tests, prothrombin time, activated partial..
Read MoreAbstract The evolution of devices for mechanical circulatory support (MCS), including ventricular assist devices (VADs) for patients with heart failure and extracorporeal membrane oxygenation (ECMO) for patients with acute cardiac..
Read MoreBackground Pump thrombosis is a major adverse event in patients supported with a left ventricular assist device (LVAD). Treatment approaches include device exchange, lytic therapy, or augmentation of anticoagulation or..
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