Tags Archives: Septic shock

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Venoarterial Extracorporeal MembraneOxygenation in Septic Shock and/or Sepsis-induced Cardiomyopathy: A Systematic Review of Fifteen Studies

Abstract Objective(s) To evaluate survival outcomes and identify candidate profiles for venoarterial extracorporeal membrane oxygenation in adult patients with sepsis-induced cardiomyopathy. Design The authors systematically searched PubMed, Embase, and Google..

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Refractory septic shock: our updatedpragmatic approach

Abstract Despite the refinement in guidelines and improving outcomes, a subset of patients with septic shock fails to respond to treatment and progresses into refractory septic shock with an associated..

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Optimal ECLS Support in Mixed Cardiogenic and Septic Shock: An ELSO Registry Analysis

Abstract Background Mixed cardiogenic and septic shock has been shown to have a higher mortality than cardiogenic shock alone and presents a unique hemodynamic phenotype. Objectives This study aimed to..

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Lactate: The Fallacy of Oversimplification

Abstract Almost a quarter of a millennium after the discovery of an acidic substance in sour milk by Swedish chemist Carl Wilhelm Scheele and more than 100 years after the..

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Hemoadsorption in the Management of Septic Shock: A Systematic Review and Meta-Analysis

Abstract Background/Objectives: Septic shock remains a significant clinical challenge with consistently high mortality rates. Recent investigations have focused on the efficacy of CytoSorb® (CytoSorbents Corporation, Monmouth Junction, NJ, USA), an extracorporeal..

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Use of extracorporeal blood purification therapies in sepsis: the current paradigm, available evidence, and future perspectives

Abstract Background Sepsis is the result of a dysregulated immune response to infection and is associated with acute organdysfunction. The syndrome’s complexity is contingent upon the underlying pathology and individual..

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Microcirculation: Current Perspective in Diagnostics, Imaging, and Clinical Applications

Abstract This review discusses the pivotal role of microcirculation in maintaining tissue oxygenation and waste removal and highlights its significance in various pathological conditions. It delves into the cellular mechanisms..

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Fluid accumulation syndrome in sepsis and septic shock: pathophysiology, relevance and treatment—a comprehensive review

Abstract In this review, we aimed to comprehensively summarize current literature on pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with sepsis/septic shock. Fluid accumulation syndrome (FAS) is..

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Extracorporeal Membrane Oxygenation for Septic Shock in Adults and Children: A Narrative Review

Abstract Refractory septic shock is associated with a high risk of death. Circulatory support in the form of veno-arterial extracorporeal membrane oxygenation (VA ECMO) may function as a bridge to..

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Venoarterial Extracorporeal Membrane Oxygenation Implementation in Septic Shock Rat Model

Abstract Septic shock, a global health concern, boasts high mortality rates. Research exploring the efficacy of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in septic shock remains limited. Our study aimed to..

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Impact of CytoSorb Hemoadsorption Therapy on Fluid Balance in Patients with Septic Shock

Abstract Recent in vitro studies have investigated the effects of hemoadsorption therapy on endothelial function in sepsis showing a reduction in markers of endothelial dysfunction, but, to this day, there..

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Adjunctive Hemoadsorption Therapy with CytoSorb in Patients with Septic/Vasoplegic Shock: A Best Practice Consensus Statement

Abstract A dysregulated host response is a common feature in critically ill patients due to both infectious and non-infectious origins that can lead to life-threatening organ dysfunction, which is still..

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CytoSorb® in Combination with CRRT in A Patient Suffering from Septic Shock, Acute Respiratory Distress Syndrome (ARDS) and Acute Kidney…

This case reports on an 53-year-old female patient who was admitted to the hospital with an 8 day history of fever and chills, loose stools, vomiting, severe weakness, and reduced..

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Peripheral Veno-Arterial-Extracorporeal Membrane Oxygenation for Refractory Septic Shock in Children: A Multicenter Review

Abstract Background Extracorporeal membrane oxygenation (ECMO) is utilized as a rescue therapy in the management of pediatric patients with refractory septic shock. Multiple studies support the use of a central..

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Prognosis of Venoarterial Extracorporeal Membrane Oxygenation in Mixed, Cardiogenic and Septic Shock

Abstract Mixed cardiogenic-septic shock (MS), defined as the combination of cardiogenic (CS) and septic (SS) shock, is often encountered in cardiac intensive care units. Herein, the authors compared the impact of..

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Tachycardia in Sepsis: Friend or Foe?

Abstract Sepsis and Tachycardia – Aetiologic Factors During sepsis, the sympathetic nervous system plays a key role in maintaining cardiac output and blood pressure. This is achieved through changes in..

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Use of CytoSorb in a patient with urosepsis and septic shock

This case reports on a 56-year-old female patient who was admitted to hospital by ambulance with fever (up to 42°C) that had been persisting for 4 days, lower abdominal pain..

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Use of CytoSorb in splenic abscessand septic shock due to intestinal ischemia following portal vein thrombosis and extensive small bowel…

This case reports on a 37-year-old male patient with known type 1 diabetes mellitus, who was admitted to the hospital with nausea, multiple vomiting and abdominal pain. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/07/CoW_28_2022_E_web_compressed.pdf"]

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The emerging concept of fluid tolerance: A position paper

Abstract Fluid resuscitation is a core component of emergency and critical care medicine. While the focus of clinicians has largely been on detecting patients who would respond to fluid therapy, relatively..

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Use of CytoSorb in septic shock with ARDS in the context of pneumonia and pulmonary hemorrhage with suspected macrophage activation…

This case reports on a 35-year-old female patient with systemic lupus erythematosus who presented to hospital with exacerbated encephalopathy under the assumption of an infection after she was found apathetic,..

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Use of CytoSorb in combined hemorrhagic and septic shock with multiple organ dysfunction following complicated surgery for pancreatic head carcinoma

This case reports on a 60-year-old male patient who presented to hospital for elective surgical treatment of carcinoma of the pancreatic head. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/02/CoW_12_2022_E_web_compressed.pdf"]

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Use of CytoSorb as stand-alone therapy in the management of septic shock with multiple organ failure due to acalculous cholecystitis

This case reports on a 44-year-old female, who was admitted to the hospital with complaints of high fever, vomiting, abdominal pain and decreased urine output for the previous 2 days...

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Use of CytoSorb in a patient with septic shock and multiple organ failure following combined mitral and aortic valve replacement

This case reports on a 58-year-old male patient who presented to the hospital for an elective cardiothoracic surgical procedure. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/12/CoW_06_2022_E_web_compressed.pdf"]  

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Extracorporeal Membrane Oxygenation for Septic Shock in Children

Abstract Extracorporeal membrane oxygenation (ECMO) is a rescue treatment used in children and adults with reversible cardiorespiratory failure. The role of ECMO is not fully established in pediatric sepsis. In..

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Postoperative use of CytoSorb in septic shock following a mitral valve replacement procedure due to infective endocarditis

This case report’s on a 65-year-old male patient who was admitted to the Department of Cardiac Surgery due to severe mitral regurgitation in the context of infective endocarditis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/01/CoW_04_2022_E_web_compressed.pdf"]

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Use of CytoSorb in a patient with postoperative septic shock following extended pancreaticoduodenectomy (Whipples procedure)

This case reports on a 49-year-old female patient who presented to hospital with locally advanced carcinoma of the pancreatic head with jaundice, weight loss, abdominal pain and ascites already manifested...

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CytoSorb in a patient with post-COVID 19 mucormycosis, septic shock and multiple organ failure

This case reports on a 47-year-old male who was admitted to the Emergency Room with tachypnea, hypotension, and post-COVID-19 mucormycosis. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2021/11/CoW_46_2021_E_web_compressed.pdf"]  

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Use of CytoSorb in a patient with SARS-CoV-2 infection and secondary septic shock with multiple organ failure

This case reports on a 67-year-old male patient who was transferred from the emergency department to the multidisciplinary intensive care unit due to severe respiratory failure from a newly diagnosed..

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Clinical Guidelines for Adult Heart Transplantation British Columbia

Abstract Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection [1]. Sepsis and septic shock are major healthcare problems, impacting millions of people around the world..

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Use of CytoSorb in a comorbid and immunocompromised patient with septic shock

This case reports on a 75-year-old male patient who was admitted to the emergency department with complaints of fever, generalized weakness, signs of chest congestion, coughing and breathing difficulties since..

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