Tags Archives: pediatric

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A Landscape Analysis of Pediatric and Congenital Heart Disease Services in Africa

Abstract Background There is geographic disparity in the provision of Pediatric and Congenital Heart Disease (PCHD) services; Africa accounts for only 1% of global cardiothoracic surgical capacity. Methods We conducted..

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Navigating coagulation: Key markers in the first 24 hours of pediatric ECMO

Abstract Background Anticoagulation in pediatric extracorporeal membrane oxygenation (ECMO) presents unique challenges due to developmental hemostasis, coagulation factor production, and response to anticoagulants. This process requires close monitoring to prevent..

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Impact of pre-bypass ultrafiltration on prime values and clinical outcomes in neonatal and infant cardiopulmonary bypass

Abstract Background: A standard blood prime for cardiopulmonary bypass (CPB) in congenital cardiac surgery may possess non-physiologic values for electrolytes, glucose, and lactate. Pre-bypass Ultrafiltration (PBUF) can make these values..

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Clinical Guidelines for Routine Neuromonitoring in Neonatal and Pediatric Patients Supported on Extracorporeal Membrane Oxygenation

Abstract Disclaimer:  These guidelines for routine neuromonitoring in neonatal and pediatric patients supported on extracorporeal membrane oxygenation (ECMO) are intended for educational use to build the knowledge of physicians and other health..

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Centrifugal Pump Generates Superior Hemodynamic Performance Compared to a new Diagonal Blood Pump in Neonatal and Pediatric ECMO Circuits

Abstract Purpose With newer generation diagonal and centrifugal blood pumps gaining popularity, the objective of this study was to compare the DP3-i-cor diagonal and RotaFlow centrifugal pumps in terms of..

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Comparison between Del Nido and conventional blood cardioplegia in pediatric open-heart surgery

Abstract Background Del Nido cardioplegia (DNc) was designed for superior myocardial protection during cardiopulmonary bypass (CPB). We conducted a retrospective review to explore if DNc was associated with increase in..

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The Fundamental Skills and Deconstructed Sub-Steps of Pediatric Cardiopulmonary Bypass

Abstract Perfusion education programs use simulation to provide students with clinical skills prior to entering the operating room. To teach the psychomotor execution of skills in a simulation lab requires..

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Plasma and Platelet Transfusions Strategies in Neonates and Children Undergoing Cardiac Surgery With Cardiopulmonary Bypass or Neonates and Children Supported…

Abstract Objectives:  To present the recommendations and consensus statements with supporting literature for plasma and platelet transfusions in critically ill neonates and children undergoing cardiac surgery with cardiopulmonary bypass or..

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2021 ELSO Adult and Pediatric Anticoagulation Guidelines

Abstract Anticoagulation is necessary for most pediatric and adult extracorporeal membrane oxygenation (ECMO) patients to prevent circuit clotting. Inherently, the most common side effect of anticoagulation is bleeding. Anticoagulation during..

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Extracorporeal Life Support for Status Asthmaticus

Abstract Extracorporeal life support (ECLS) may be life saving for patients with status asthmaticus (SA), a difficult-to-treat, severe subset of asthma. Contemporary ECLS outcomes for SA in teens and young..

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Hemoadsorption as bridge to liver transplant in a six-month old patient with hepatic failure

This case reports on a 6-month-old female patient (8 kg, 55 cm), who was admitted to the hospital due to severe hyperbilirubinemia. [pdf-embedder url="https://perfusfind.com/wp-content/uploads/2022/01/CoW_03_2022_E_web_compressed.pdf"]  

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How to best monitor bivalirudin anticoagulant effect for ECMO and VAD—Comparison of four assay methods

Abstract Introduction Unfractionated heparin is widely used as an anticoagulant for extracorporeal life support (ECLS) and usually monitored with activated partial thromboplastin time (aPTT). Due to its limitations in pediatric..

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Use of Extracorporeal Membrane Oxygenation in Acutely Poisoned Pediatric Patients in United States

Abstract Objectives:  To describe the use of extracorporeal membrane oxygenation (ECMO) in the management of pediatric poisoning in the United States and to identify predictors of mortality. Design:  Retrospective cohort study. Setting: ..

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Pediatric Extracorporeal Life Support Transport in Western Canada

Abstract This retrospective cohort study describes all children transported on extracorporeal life support (ECLS) by the Stollery Children’s Hospital Pediatric Transport team (SCH-PTT) between 2004 and 2018. We compared outcomes..

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Characterizing Sleep Disruption and Delirium in Children After Cardiac Surgery: A Feasibility Study

Abstract OBJECTIVES:  Patients in the pediatric cardiac ICU are frequently exposed to pharmacologic and environmental factors that predispose them to sleep disturbances and may increase the risk of delirium. In..

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Pharmacokinetics of Antibiotics in Pediatric Intensive Care: Fostering Variability to Attain Precision Medicine

Abstract Children show important developmental and maturational changes, which may contribute greatly to pharmacokinetic (PK) variability observed in pediatric patients. These PK alterations are further enhanced by disease-related, non-maturational factors...

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Ex Vivo Allograft Perfusion for Complex Pediatric Heart Transplant Recipients

Abstract Background Pediatric heart transplant (HTx) recipients with congenital heart defects require complex concomitant surgical procedures with the risk of prolonging the allograft’s ischemic time. Ex vivo allograft perfusion with the..

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Outcomes of Pediatric Patients With Sepsis Related to Staphylococcus aureus and Methicillin-Resistant Staphylococcus aureus Infections Requiring Extracorporeal Life Support: An…

Abstract Background: Extracorporeal membrane oxygenation (ECMO) is increasingly utilized for pediatric sepsis unresponsive to steroids and inotropic support. Outcomes of children with sepsis are influenced by the type of pathogen causing..

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Bi-Caval Dual Lumen Catheter for Pediatric Patients Undergoing Venovenous Extracorporeal Membrane Oxygenation

Abstract An 11-year-old female patient was admitted to a pediatric intensive care unit for the treatment of acute respiratory distress syndrome (ARDS). She had received peripheral blood stem cell transplantation..

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Interrelations of Intraoperative Changes in Cerebral Tissue Oxygen Saturation with Brain Volumes and Neurodevelopment Outcome After the Comprehensive Stage II…

Abstract Objectives The monitoring of cerebral tissue oxygen saturation by near-infrared spectroscopy (ScerebO2) is used widely in pediatric cardiac anesthesia. However, little information is available on the effects of changes..

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Use of CytoSorb in the treatment of a pediatric patient with acute hepatitis C complicated by HIV, toxic hepatitis, and…

The case reports on a 17-year-old boy (weight 70 kg) transferred to the Children Infections Research Center intensive care unit (ICU) with severe jaundice and in a poor general condition..

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Methylprednisolone Plasma Concentrations During Cardiac Surgery With Cardiopulmonary Bypass in Pediatric Patients

Abstract Introduction: To our knowledge, methylprednisolone pharmacokinetics and plasma concentrations have not been comprehensively investigated in children with congenital heart disease undergoing cardiac surgery with cardiopulmonary bypass. It is unknown whether..

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Blood pressure variability during pediatric cardiac surgery is associated with acute kidney injury

Abstract Background Blood pressure variability (BPV), defined as the degree of variation between discrete blood pressure readings, is associated with poor outcomes in acute care settings. Acute kidney injury (AKI)..

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Use of CytoSorb in case of operative extraction of the massive right atrium thrombus associated with Hickman catheter in Non-Hodgkin…

This case reports on a 16-year-old male patient (weight 56 kg), who was admitted from the hematology-oncology ward to the Pediatric Intensive Care Unit (PICU) after a clinical deterioration with..

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Centrifugal and Roller Pumps in Neonatal and Pediatric Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) is an invaluable means of supporting critically ill children with refractory respiratory or cardiac failure. Controversy remains; however, whether roller or centrifugal pumps are superior,..

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Nomenclature for Pediatric and Congenital Cardiac Care: Unification of Clinical and Administrative Nomenclature – The 2021 International Paediatric and Congenital…

Abstract Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas of Congenital Cardiac Disease, which was..

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Similar frequency of atrial perforation between atrial and bicaval dual lumen veno-venous ECMO cannulas in a pediatric population

Abstract Purpose: Complications associated with use of dual-lumen venovenous extracorporeal membrane oxygenation (VV-ECMO) cannulas are of concern in pediatric patients. While the risk of atrial perforation is believed to be..

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Subzero balance - simple modified ultrafiltration (SBUF-SMUF) technique for pediatric cardiopulmonary bypass

Abstract The use of cardiopulmonary bypass (CPB) can be associated with significant hemodilution, coagulopathy and a systemic inflammatory response for infants and children undergoing cardiac surgery. Intra-operative ultrafiltration has been..

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Efficacy of CytoSorb in a Pediatric Case of Severe Multisystem Inflammatory Syndrome (MIS-C): A Clinical Case Report

This case reports on a 14-year-old previously healthy girl who was referred to the Pediatric Intensive Care Unit (PICU) with a suspicion of multisystem inflammatory syndrome in children (MIS-C) and..

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Postoperative Cerebral Oxygen Saturation in Children After Congenital Cardiac Surgery and Long-Term Total Intelligence Quotient: A Prospective Observational Study

Abstract OBJECTIVES:  During the early postoperative period, children with congenital heart disease can suffer from inadequate cerebral perfusion, with possible long-term neurocognitive consequences. Cerebral tissue oxygen saturation can be monitored..

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