Etiquetas Archivo: Out-of-hospital cardiac arrest (OHCA)

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Prehospital Ground and Helicopter-Based Extracorporeal Cardiopulmonary Resuscitation (ECPR) Reduce Barriers to ECPR: A GIS Model

Abstract Introduction Evidence suggests that Extracorporeal Cardiopulmonary Resuscitation (ECPR) can improve survival rates for nontraumatic out-of-hospital cardiac arrest (OHCA). However, when ECPR is indicated over 50% of potential candidates are..

Lee mas
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Left ventricular unloading during VA-ECMO: A Gordian knot of physiology

Abstract Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a powerful hemodynamic support strategy for patients with cardiogenic shock and out-of-hospital cardiac arrest (OHCA).  Given that significant proportions of patients presenting with..

Lee mas
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Extracorporeal cardiopulmonary resuscitation versus conventional CPR in cardiac arrest: an updated meta‑analysis and trial sequential analysis

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) may reduce mortality and improve neurological outcomes in patients with cardiac arrest. We updated our existing meta-analysis and trial sequential analysis to further evaluate..

Lee mas
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Accredited cardiac arrest centers facilitate eCPR and improve neurological outcome

Abstract Background Out-of-hospital cardiac arrest (OHCA) remains a frequent medical emergency with low survival rates even after a return of spontaneous circulation (ROSC). Growing evidence supports formation of dedicated teams..

Lee mas
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The state of emergency department extracorporeal cardiopulmonary resuscitation: Where are we now, and where are we going?

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) has emerged in the context of the emergency department as a life-saving therapy for patients with refractory cardiac arrest. This review examines the utility of..

Lee mas
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Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: 10-year experience in a metropolitan cardiac arrest centre in Milan, Italy

Abstract Introduction Growing evidence supports  cardiopulmonary resuscitation (ECPR) for refractory out-of-hospital cardiac arrest (OHCA) patients, especially in experienced centres. We present characteristics, , and outcomes of patients treated with ECPR in a..

Lee mas
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Pre-hospital ECPR in an Australian metropolitan setting: a single-arm feasibility assessment—The CPR, pre-hospital ECPR and early reperfusion (CHEER3) study

Abstract Introduction Survival from refractory out of hospital cardiac arrest (OHCA) without timely return of spontaneous circulation (ROSC) utilising conventional advanced cardiac life support (ACLS) therapies is dismal. CHEER3 was..

Lee mas
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Should we give steroids after out‑of‑hospital cardiac arrest?

Abstract The pathophysiology of post-cardiac arrest syndrome features ischaemic/reperfusion injury and the release of high levels of inflammatory cytokines [1]. These inflammatory markers include interleukin-6 (IL-6), C-reactive protein (CRP), tumour..

Lee mas
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Impact of age on survival for patients receiving ECPR for refractory out-of-hospital VT/VF cardiac arrest

Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) has been shown to improve neurologically favorable survival for patients with refractory ventricular tachycardia (VT)/ventricular fibrillation (VF) out-of-hospital cardiac arrest. Prior studies of the impact of age..

Lee mas
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Prehospital high‑dose methylprednisolone in resuscitated out‑of‑hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

Abstract Purpose: Patients who are successfully resuscitated following out‑of‑hospital cardiac arrest (OHCA) are still at a highrisk of neurological damage and death. Inflammation and brain injury are components of the..

Lee mas
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Organ Donation After Out-of-Hospital Cardiac Arrest: A Scientific Statement From the International Liaison Committee on Resuscitation

Abstract Aim of the Review: Improving rates of organ donation among patients with out-of-hospital cardiac arrest who do not survive is an opportunity to save countless lives. The objectives of..

Lee mas
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Serum lactate in refractory out-of-hospital cardiac arrest: Post-hoc analysis of the Prague OHCA study

Abstract Background The severity of tissue hypoxia is routinely assessed by serum lactate. We aimed to determine whether early lactate levels predict outcomes in refractory out-of-hospital cardiac arrest (OHCA) treated..

Lee mas
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ECPR for refractory OHCA – lessons from 3 randomized controlled trials. The trialists´view

Abstract Extracorporeal cardiopulmonary resuscitation is a promising treatment for refractory out-of-hospital cardiac arrest. Three recent randomized trials (ARREST-trial, Prague OHCA study, and INCEPTION-trial) that addressed the clinical benefit of ECPR..

Lee mas
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Coronary angiography findings in resuscitated and refractory out-of-hospital cardiac arrest: A systematic review and meta-analysis

Abstract Introduction Coronary angiography (CAG) frequently reveals coronary artery disease (CAD) after out-of-hospital cardiac arrest (OHCA), but its use is not standardized and often reported in different subpopulations. This systematic..

Lee mas
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What is the potential benefit of pre-hospital extracorporeal cardiopulmonary resuscitation for patients with an out-of-hospital cardiac arrest? A predictive modelling…

Abstract Aim In this  study we aimed to investigate how many  with an out-of-hospital cardiac arrest (OHCA) would benefit from pre-hospital as opposed to in-hospital initiation of  cardiopulmonary resuscitation (ECPR). Methods A  of Utstein..

Lee mas
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Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with cardiac arrest: a comparative meta-analysis and trial sequential analysis

Abstract Background Although outcomes of patients after cardiac arrest remain poor, studies have suggested that extracorporeal cardiopulmonary resuscitation (ECPR) might improve survival and neurological outcomes. We aimed to investigate any..

Lee mas
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Intraarrest transport, extracorporeal cardiopulmonary resuscitation, and early invasive management in refractory out-of-hospital cardiac arrest: an individual patient data pooled analysis…

Abstract Background Refractory out-of-hospital cardiac arrest (OHCA) treated with standard advanced cardiac life support (ACLS) has poor outcomes. Transport to hospital followed by in-hospital extracorporeal cardiopulmonary resuscitation (ECPR) initiation may..

Lee mas
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Refractory out-of-hospital cardiac arrest and extracorporeal cardiopulmonary resuscitation: A meta-analysis of randomized trials

Abstract Background In adults with refractory out-of-hospital cardiac arrest, when conventional cardiopulmonary resuscitation (CPR) alone does not achieve return of spontaneous circulation, extracorporeal CPR is attempted to restore perfusion and..

Lee mas
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Out-of-hospital cardiac arrest

Abstract Cardiac arrest science continues to evolve and in the last two years many cardiac arrest clinical trials have been published in high-impact journals. In this manuscript we have selected 6..

Lee mas
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Regional Cerebral Oxygen Saturation to Predict Favorable Outcome in Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis

Abstract Objective This systematic review and meta-analysis aimed to investigate the role of regional cerebral oxygen saturation (rSO2) in predicting survival and neurologic outcomes after extracorporeal cardiopulmonary resuscitation (ECPR). Design..

Lee mas
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Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest

Abstract BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on..

Lee mas
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Survival and neurological outcome after out-of-hospital cardiac arrest treated with and without mechanical circulatory support

Abstract Aim The aim of this study was to describe the survival and neurological outcome in patients with  treated with and without mechanical  (MCS). Methods This was a retrospective observational  on patients with..

Lee mas
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Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital…

Abstract Importance: Out-of-hospital cardiac arrest (OHCA) has poor outcome. Whether intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and immediate invasive assessment and treatment (invasive strategy) is beneficial in this setting remains uncertain...

Lee mas
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Improving access to extracorporeal membrane oxygenation for out of hospital cardiac arrest: pre‑hospital ECPR and alternate delivery strategies

Abstract Background: The use of extracorporeal membrane oxygenation (ECPR) in refractory out-of-hospital cardiac arrest (OHCA) patients is usually implemented in-hospital. As survival in ECPR patients is critically time-dependent, alternative models..

Lee mas
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Extracorporeal versus conventional cardiopulmonary resuscitation for refractory out‑of‑hospital cardiac arrest: a secondary analysis of the Prague OHCA trial

Abstract Background: Survival rates in refractory out-of-hospital cardiac arrest (OHCA) remain low with conventional advanced cardiac life support (ACLS). Extracorporeal life support (ECLS) implantation during ongoing resuscitation, a method called..

Lee mas
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Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: first results and outcomes of a newly established ECPR program in a large…

Abstract Objectives: Out-of-hospital cardiac arrest (OHCA) is associated with excessively high mortality rates. Recent studies suggest benefits from extracorporeal cardiopulmonary resuscitation (ECPR) performed in selected patients. We sought to present..

Lee mas