Tags Archives: organ dysfunction

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Biomarkers of multi-organ dysfunction in ECMO: prognostic signposts for palliative transitions

Abstract Consistently high lactate levels and poor clearance on ECMO are important early signs of poor perfusion and useless care. For example, lactate levels over 8 mmol/L at 12 h, staying above..

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Predictive role of cardiopulmonary bypass exposure indexed to body surface area on postoperative organ dysfunction: a retrospective cohort study

Abstract OBJECTIVES Long cardiopulmonary bypass times are associated with adverse postoperative outcomes and increased healthcare resource use. It is likely that this effect is pronounced in smaller patients. Previous studies..

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Altered Microvascular Reactivity During a Skin Thermal Challenge Is Associated With Organ Dysfunction and Slow Recovery After Cardiac Surgery

Abstract Objectives To assess microvascular reactivity during a skin thermal challenge early post-cardiac surgery and its association with outcomes. Design Noninvasive physiological study. Setting Thirty-five-bed department of intensive care. Participants..

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Association between lactic acidosis and multiple organ dysfunction syndrome after cardiopulmonary bypass

Abstract Background The relationship between hyperlactatemia and prognosis after cardiopulmonary bypass (CPB) is controversial, and some studies ignore the presence of lactic acidosis in patients with severe hyperlactacemia. This study..

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Unresponsive Low Mixed Venous Oxygen Saturation During Early Intensive Care Unit Stay is Associated With Increased Risk of Organ Dysfunction…

Abstract Objectives The aim of the study was to determine if unresponsive mixed venous  (SvO2) values during early postoperative hours are associated with postoperative organ dysfunction. Design A single-center retrospective observational..

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The Disconnect Between Extracorporeal Circulation and the Microcirculation

Abstract Extracorporeal circulation (ECC) procedures, such as cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), take over the function of one or more organs, providing clinicians time to treat underlying..

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