Tags Archives: microcirculation

Perfusfind S.L.

Abstract Introduction Intra-operative hypotension is common during cardiopulmonary bypass and may contribute to tissue hypoxia. Tissue hypoxia has been linked to the development of postoperative kidney and brain injury. Vasopressors..

Perfusfind S.L.

Abstract Background Ascorbic acid is an essential cofactor of catecholamine synthesis that increases capillary bed density and improves microcirculation perfusion. We hypothesized early ascorbic acid administration in cardiothoracic surgery would..

Perfusfind S.L.

Abstract Objective.  Continuous monitoring of the hemodynamic coherence between macro and microcirculation is difficult at the bedside. We tested the role of photoplethysmography (PPG) to real-time assessment of microcirculation during..

Perfusfind S.L.

Abstract This review discusses the pivotal role of microcirculation in maintaining tissue oxygenation and waste removal and highlights its significance in various pathological conditions. It delves into the cellular mechanisms..

Perfusfind S.L.

Abstract Microcirculation is essential for cellular life and its functions. It comprises a complex network of capillaries, arterioles, and venules, which distributes oxygenated blood across and within organs based on..

Perfusfind S.L.

Abstract The  describes the network of the smallest vessels in our cardiovascular system. On a microcirculatory level, oxygen delivery is determined by the flow of oxygen-carrying  in a given single capillary (capillary..

Perfusfind S.L.

Abstract Introduction Microcirculatory dysfunction after  is associated with significant morbidity and worse clinical outcomes. Abnormal  can occur from multiple causes, including cytokine-mediated vascular , , and an inadequate balance between  and . In response to ,  produce cellular  (CAMs)..

Perfusfind S.L.

Abstract Extracorporeal circulation (ECC) procedures, such as cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), take over the function of one or more organs, providing clinicians time to treat underlying pathophysiological..

Perfusfind S.L.

Abstract Purpose Venoarterial  (VA ECMO) effectively supports refractory  (rCS), and sustains macro- and . We investigated the respective impact of increasing VA ECMO flow or  dose on microcirculation in stabilized VA ECMO–treated patients with..

Perfusfind S.L.

Abstract Extracorporeal membrane oxygenation (ECMO) is a procedure used to aid respiratory function in critical patients, involving extracorporeal circulation (ECC) of blood. There is a limited number of studies quantifying..

Perfusfind S.L.

Abstract Extracorporeal circulation (ECC) procedures, such as cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), take over the function of one or more organs, providing clinicians time to treat underlying..

Perfusfind S.L.

Abstract Background Acute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and microcirculatory perfusion disturbances. CPB-induced thrombin release results in capillary hyperpermeability..

Perfusfind S.L.

Abstract A prospective, observational single-center study was carried out. Pediatric patients undergoing congenital heart defect surgery were evaluated before, during, and after surgery. At each time point, sublingual microcirculation and..

Perfusfind S.L.

Abstract Microcirculatory disturbances are commonplace after cardiopulmonary bypass.  Postoperative atrial fibrillation (POAF) occurs in nearly 30% of patients undergoing conventional cardiac surgery.  Landiolol, a short-acting i.v. beta blocker, could reduce..

Perfusfind S.L.

Where is the seat of the soul? Historical and contemporary beliefs are explored. Is it the heart, the brain, or somewhere else?  The microcirculation? Philosophical concepts are explored by a..

Perfusfind S.L.

Dr. Keshen Mathura discusses the MicroVision microvascular scanner and discusses and demonstrates how this tool to visualize the microcirculation can be used in the cardiac and critical care units to..

Perfusfind S.L.

Keshen Mathura, M.D., PhD, founder, developer and chief science officer of MicroVision Scan, Inc, a device that uses Side-stream Dark Field Imaging (SDF) to view, in real time, the capillary..

Perfusfind S.L.

RESUMEN  La vía final común de los efectos de la circulación extracorpórea es la hipoperfusión periférica, que se valora indirectamente a través de la utilización de O2 en la periferia. El Orthogonal..

Perfusfind S.L.

Abstract OBJECTIVES Closed minimal extracorporeal circulation (MECC) systems currently do not represent the standard of surgical care for open-heart surgery. Yet, considering the beneficial results reported for coronary artery bypass..

Perfusfind S.L.

Abstract The microcirculation is a major topic in current physiology textbooks and is frequently explained with schematics including the precapillary sphincters and metarterioles. We re-evaluated the validity and applicability of..

Perfusfind S.L.

Abstract Background In this study we aimed to evaluate the effects of dilutional anemia resulting from cardiopulmonary bypass (CPB) and its correction with red blood cell (RBC) transfusion on tissue..

Perfusfind S.L.

Abstract Objective To evaluate parameters of the  test (VOT) before, during, and after pulsatile  (CPB). Design Prospective, . Setting Single-center university hospital. Participants Adult patients undergoing elective cardiac surgery with pulsatile CPB. Interventions..

Perfusfind S.L.

Abstract Obesity is a frequent comorbidity among patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). Cardiac surgery with CPB impairs microcirculatory perfusion, which is associated with multiple organ failure. As..

Perfusfind S.L.

Abstract Objective Cardiac surgery and  are associated with release of  and microcirculatory alterations that result in organ dysfunction. Near-infrared  of tissue  (StO2) and the  test (VOT) were utilized in a study of elective cardiac surgical..

Perfusfind S.L.

Abstract Background: We designed a non-invasive, observational, real-time study, using near-infrared spectroscopy (NIRS) to assess the in vivo effects of cardiopulmonary bypass (CPB) on patients’ skeletal muscle as well as..

Perfusfind S.L.

Abstract Summary We investigated microcirculatory perfusion disturbances following cardiopulmonary bypass in the early postoperative period and whether the course of these disturbances mirrored restoration of endothelial glycocalyx integrity. We performed..

Perfusfind S.L.

Abstract  In this review the impact of cardiopulmonary bypass (CPB) on the microcirculation is discussed. The impact of conventional non-pulsatile perfusion is contrasted with the microcirculatory impact of pulsatile CPB..

Perfusfind S.L.

Abstract Background Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier..

Perfusfind S.L.

Introduction Lactic acidosis after cardiac surgery with cardiopulmonary bypass is common and associated with an increase in postoperative morbidity and mortality. A number of potential causes for an elevated lactate..