Abstract Objectives To assess whether intravenous lidocaine reduces the systemic inflammatory response associated with cardiopulmonary bypass (CPB) and improves clinical outcomes in adult patients undergoing elective valvular and/or coronary cardiac..
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Abstract Background Lidocaine in del Nido cardioplegia solution prolongs the refractory period of cardiomyocytes, yielding a longer arrest per dose. Serum lidocaine concentrations >8 mg/L are associated with seizure and..
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Abstract Purpose Postoperative cognitive dysfunction (POCD) occurs frequently after cardiac surgery. The pathophysiology of POCD remains elusive, but previous work showed that intravenous lidocaine may be protective against POCD, possibly..
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