Tags Archives: kidney injury

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Kidney Injury under Diminished Pulsatile Flow Induced by V-A ECMO in Sheep

Abstract Extracorporeal membrane oxygenation (ECMO) is commonly used for critically ill patients and associated with high rates of kidney injury and mortality. This study aimed to assess the impact of..

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Kidney Injury Following Cardiac Surgery: A Review of Our Current Understanding

Abstract Around one-quarter of all patients undergoing cardiac procedures, particularly those on cardiopulmonary bypass, develop cardiac surgery-associated acute kidney injury (CSA-AKI). This complication increases the risk of several serious morbidities..

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The Nephroprotective Effect of Nitric Oxide during Extracorporeal Circulation: An Experimental Study

Abstract This study aims to determine the effectiveness of administering 80 ppm nitric oxide in reducing kidney injury, mitochondrial dysfunction and regulated cell death in kidneys during experimental perfusion. Twenty-four..

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The Preventive Role of Glutamine Supplementation in Cardiac Surgery-Associated Kidney Injury from Experimental Research to Clinical Practice: A Narrative Review

Abstract Acute kidney injury represents a significant threat in cardiac surgery regarding complications and costs. Novel preventive approaches are needed, as the therapeutic modalities are still limited. As experimental studies..

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NO Addition during Gas Oxygenation Reduces Liver and Kidney Injury during Prolonged Cardiopulmonary Bypass

Abstract Objective. To evaluate the effect of NO added to the sweep gas of the oxygenator during cardiopulmonary bypass (CPB) on the liver and kidneys in pigs.  Methods. An experiment..

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Improved creatinine-based early detection of acute kidney injury after cardiac surgery

Abstract   OBJECTIVES This study aims to improve early detection of cardiac surgery-associated acute kidney injury (CSA-AKI) compared to classical clinical scores. METHODS Data from 7633 patients who underwent cardiac..

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The impact of minimal invasive extracorporeal circulation on postoperative kidney function

Abstract Introduction: Acute kidney injury following cardiac surgery is a frequent complication associated with increased mortality and morbidity. Minimal invasive extracorporeal circulation is suggested to preserve postoperative renal function. The..

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Is the use of hydroxyethyl starch as priming solution during cardiac surgery advisable? A randomized, single-center trial

Abstract Introduction: The use of cardiopulmonary bypass (CPB) leads to increased fluid filtration and edema. The use of artificial colloids to counteract fluid extravasation during cardiac surgery is controversial. Beneficial..

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Effects of remote ischemic preconditioning in high-risk patients undergoing cardiac surgery (Remote IMPACT): a randomized controlled trial

Abstract Background:  Remote ischemic preconditioning is a simple therapy that may reduce cardiac and kidney injury. We undertook a randomized controlled trial to evaluate the effect of this therapy on..

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