Tags Archives: infection

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Association Between Intraoperative Hyperlactatemia and Infection After Cardiac Surgery With Cardiopulmonary Bypass: A Multicenter Retrospective Study

Abstract Objectives To test the hypotheses that intraoperative hyperlactatemia is independently associated with increased postoperative infection risk in cardiac surgery with cardiopulmonary bypass (CPB). Methods This study involved 4970 cardiac..

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Perioperative tight glucose control regimens for preventing surgical site infections following cardiac surgery-a systematic review and metanalysis of randomized controlled…

Abstract Background Perioperative hyperglycemia is common during cardiac surgery and has been linked to an increased risk of surgical site infections (SSIs). However, the benefits of perioperative tight glucose control..

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Incidence of Healthcare-Associated Infections in Patients on Extracorporeal Membrane Oxygenation Secondary to Respiratory or Cardiac Failure: A Retrospective Cohort Study

Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life support technique used in patients with respiratory or cardiac failure. Despite the increased use of ECMO, the incidence and risk factors..

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Antimicrobial pharmacokinetics and stewardship in critically Ill adult patients receiving ECMO: Challenges, evidence, and future directions

Abstract Infection is a common indication and complication for extracorporeal membrane oxygenation (ECMO), and adult ECMO recipients face increased nosocomial infection risk. Effective antimicrobial dosing in these patients remains difficult..

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Effect of surgical site infection bundles in cardiac surgery: Incidence, microbiology, and risk factors

Abstract Background: Surgical site infections are the second most common type of healthcare-associated infection. Objective: This study aimed to assess the incidence and associated risk factors of surgical site infection..

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Infection risks in patients treated by continuous renal replacement therapy and extracorporeal membrane oxygenation

Abstract Purpose of review  This review addresses the growing concern over nosocomial infections in patients undergoing extracorporeal membrane oxygenation (ECMO) and/or continuous renal replacement therapy (CRRT). As the use of..

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Hospital-acquired infections in neonatal ECMO patients: a systematic review and meta-analysis

Abstract To evaluate the impact of hospital-acquired infections ( HAIs ) on the prognosis of neonates treated with extracorporeal membrane oxygenation (ECMO) and analyzing related prognostic indicators, we conducted a..

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Development, validation, and clinical evaluation of a machine-learning based model for diagnosing early infection after cardiovascular surgery (DEICS): a multi-center…

Abstract Background:  This study addresses the critical need for timely and accurate diagnosis of early postoperative infection (EPI) following cardiac surgery. EPI significantly impacts patient outcomes and healthcare costs, making..

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Prevalence, Risk Factors, and Outcomes of Hospital-Acquired Infections in Children After Congenital Heart Surgery

Abstract Background Hospital-acquired infections (HAIs) are associated with morbidity and mortality in children following congenital cardiac surgery. Our center performs approximately 200 congenital surgeries a year, but infection rates and..

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Implementation of Bundled Interventions to Reduce Surgical Site Infections in Pediatric Patients Undergoing Cardiothoracic Surgery: A Quality Improvement Project

Abstract Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures are associated with prolonged lengths of stay and..

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Interhospital variability in 180-day infections following cardiac surgery

Abstract Objective To evaluate hospital-level variation in infections following cardiac surgery and develop and evaluate a 180-day infection quality metric. Methods This study evaluated Medicare claims that were merged with..

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Interventions to prevent surgical site infection in adults undergoing cardiac surgery

Abstract Background Surgical site infection (SSI) is a common type of hospital‐acquired infection and affects up to a third of patients following surgical procedures. It is associated with significant mortality..

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A systematic review of variability in the reporting of extracorporeal membrane oxygenation-associated infections and recommendations for standardization

Abstract Background Extracorporeal membrane oxygenation (ECMO) utilization has surged in recent years, particularly amidst the COVID-19 pandemic, yet standardization of ECMO-associated infection (EAI) reporting remains lacking. Methods This systematic review..

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Extracorporeal Membrane Oxygenation Cannulae-related Infection: Diagnostic Difficulties and Potential Prevention

Abstract We read with interest the recently-published article by Winiszewski et al. detailing the prevalence and risk factors associated with extracorporeal membrane oxygenation (ECMO) cannulae-related infections (CRIs). Winiszewski highlights a number of..

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Chlorhexidine bathing of the exposed circuits in extracorporeal membrane oxygenation: an uncontrolled before-and-after study

Abstract Background Although the prevention of extracorporeal membrane oxygenation (ECMO) catheter-related infection is crucial, scientific evidence regarding best practices are still lacking. Methods We conducted an uncontrolled before-and-after study to..

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A Retrospective Study of Infection in Patients Requiring Extracorporeal Membrane Oxygenation Support

Abstract Background Healthcare-associated infections (HAIs) in critically ill patients are a serious public health problem. Extracorporeal membrane oxygenation (ECMO) has been used increasingly for patients with severe cardiac or respiratory..

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Procalcitonin and Early Postoperative Infection After Pediatric Cardiopulmonary Bypass Surgery

Abstract Objectives Systemic inflammation and bacterial infections are critical occurrences after pediatric cardiac surgery. Elevated white blood cell count and C-reactive protein cannot discriminate between these two conditions in the..

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The diagnostic accuracy of procalcitonin in infectious patients after cardiac surgery: a systematic review and meta-analysis

Abstract Cardiac surgery with cardiopulmonary bypass (CPB) induces an acute inflammatory response that may lead to a systemic inflammatory response syndrome. The interest in procalcitonin (PCT) in the diagnosis of..

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Mycobacterium chimaera: The ethical duty to disclose the minimal risk of infection to exposed patients

Abstract A recent study by Sommerstein and colleagues has demonstrated a causal link between Mycobacterium chimaera infection and the LivaNova PLC Stöckert 3T heater-cooler system (LivaNova PLC, London, United Kingdom) used in cardiac..

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Sepsis-induced myocardial dysfunction: pathophysiology and management

Abstract Sepsis is aggravated by an inappropriate immune response to invading microorganisms, which occasionally leads to multiple organ failure. Several lines of evidence suggest that the ventricular myocardium is depressed..

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Developing a New Definition and Assessing New Clinical Criteria for Septic Shock

Abstract Importance  Septic shock currently refers to a state of acute circulatory failure associated with infection. Emerging biological insights and reported variation in epidemiology challenge the validity of this definition.Objective  To develop..

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Bacterial Biofilms on Extracorporeal Membrane Oxygenation Catheters

Abstract Despite the advantages of extracorporeal membrane oxygenation (ECMO), secondary catheter infection remains a major concern during ECMO support. In this study, to clarify the mechanism of ECMO catheter-related infection, we evaluated the..

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