Abstract Background Intraoperative hypotension (IOH), defined as a mean arterial pressure (MAP) below 65 mmHg, is a common complication during surgery and is associated with significant postoperative morbidity, including acute..
Read MoreAbstract Objective To determine if the route of administration of whole blood cardioplegia (cardioplegia) is significantly associated with the frequency of profound transient hypotension (intermittent “vasoplegia”) often observed during cardioplegia..
Read MoreAbstract BACKGROUND: Current blood pressure management strategies cannot accommodate large interindividual variations in cerebral autoregulation, which may result in inadvertent cerebral ischemia. A novel optical neuromonitoring device was developed to..
Read MoreAbstract Epinephrine, the standard treatment for anaphylaxis, is a lifesaving medication that can cause detrimental complications due to wrong-dose or wrong-route errors. Although the known toxicities of epinephrine such as..
Read MoreAbstract Background Intraoperative hypotension is a common side effect of general anaesthesia and might lead to inadequate organ perfusion. It is unclear to what extent hypotension during noncardiac surgery is..
Read MoreAbstract To the editor, Hypotension is a common complication during surgery that is caused by many factors. Among these causes, acute pulmonary is extremely rare. However, once it happens, the severe hypotension..
Read MoreAbstract BACKGROUND: Vasopressors are a cornerstone for the management of vasodilatory hypotension. Vasopressor infusions are currently adjusted manually to achieve a predefined arterial pressure target. We have developed a closed-loop..
Read MoreAbstract Objective To conduct a pilot feasibility and physiologic efficacy study of high-dose vitamin C in patients with vasoplegia after cardiac surgery. Design Prospective, double-blind, randomized, controlled trial. Setting Two..
Read MoreAbstract What We Already Know about This Topic Ischemic stroke after cardiac surgery is a devastating complication affecting approximately 2% of patients The relationship between hypotension occurring before, during, and..
Read MoreAbstract Objective The hypotension prediction index (HPI) is a novel parameter developed by Edwards Lifesciences (Irvine, CA) that is obtained through an algorithm based on arterial pressure waveform characteristics. Past..
Read MoreAbstract This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of a higher versus lower blood pressure target during..
Read More








