Tags Archives: haptoglobin

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Influence of Pre-emptive Haptoglobin on Postoperative Acute Kidney Injury in Cardiac Surgical Patients: A Randomized Controlled Trial

Abstract BACKGROUND:  Haptoglobin may reduce hemolysis-induced kidney injury in patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB). Haptoglobin may be given empirically when hemolytic urine is observed, or pre-emptively when..

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Early Haptoglobin Decrease During a Microaxial Flow Pump Support: Association With High Pump Performance Level

Abstract Hemolysis is a recognized complication of a microaxial flow pump (Impella CP) support, but its incidence and associated risk factors remain unclear. We retrospectively analyzed 24 patients with cardiogenic..

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Haptoglobin Administration for Intravascular Hemolysis: A Systematic Review

Abstract Introduction Exogenous haptoglobin administration may enhance plasma-free hemoglobin (pfHb) clearance during hemolysis, and reduce its end-organ damage: we sought to systematically review and summarize available evidence on the use..

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HAPTOGLOBIN DEPLETION DURING THE FIRST 7 DAYS OF VENO-VENOUS EXTRACORPOREAL MEMBRANE OXYGENATION THERAPY IS ASSOCIATED WITH INCREASED MORTALITY AND ADVERSE…

Abstract Background: Hemolysis is a frequent complication in patients with sepsis, ARDS, or extracorporeal membrane oxygenation (ECMO). Haptoglobin (Hp) can scavenge released cell-free hemoglobin (CFH). Hemolysis and low plasma concentrations of..

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Perioperative Serum Free Hemoglobin and Haptoglobin Levels in Valvular and Aortic Surgery With Cardiopulmonary Bypass: Their Associations With Postoperative Kidney…

Abstract Highlights • Hemolysis due to CPB leads to an increase of serum free Hemoglobin(fHb) level. • Increase of serum fHb level had an independent association with postoperative AKI. •..

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