Tags Archives: ecmo

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The biological role and future therapeutic uses of nitric oxide in extracorporeal membrane oxygenation, a narrative review

Abstract Background Nitric oxide (NO) is a gas naturally produced by the human body that plays an important physiological role. Specifically, it binds guanylyl cyclase to induce smooth muscle relaxation...

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Concerning Rate of Poor Long-term Neurologic Outcomes After ECMO

Abstract Long-term neuropsychiatric symptoms as well as neurologic and functional impairment are common in patients who receive extracorporeal membrane oxygenation (ECMO) support, results of a new meta-analysis showed. More than..

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Predictors And Outcomes Of Ecmo In Patients With Thrombophilia: Insights From A Nationwide Database

Abstract Introduction Thrombophilic disorders increase the risk of blood  and are associated with morbidity in various settings. However, the impact of  on ECMO (Extracorporeal membrane oxygenation) patients is not well studied. We..

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Continuous Monitoring of Cerebral Autoregulation in Adults Supported by Extracorporeal Membrane Oxygenation

Abstract Background: Impaired cerebral autoregulation (CA) is one of several proposed mechanisms of acute brain injury in patients supported by extracorporeal membrane oxygenation (ECMO). The primary aim of this study was..

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Gaseous Nitric Oxide-Cangrelor Combination to Prevent Clots in Extracorporeal Life Support System

Abstract Introduction The objective of this study was to investigate the potential synergistic utility of a combination of gaseous nitric oxide (gNO)-intravenous Cangrelor as an effective pharmacological option for the..

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Cardiac tamponade complicating extracorporeal membrane oxygenation: an Extracorporeal Life Support Organization Registry analysis.

Abstract Objectives  is a potentially life-threatening complication during  (ECMO). In this study, we assessed the incidence, , and risk factors for mortality of cardiac tamponade during ECMO. Design We queried the  Organization (ELSO)..

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Appropriate timing of veno‑arterial extracorporeal membrane oxygenation initiation after cardiac surgery

Abstract Background Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can be initiated during cardiac surgery or later in ICU according to the hemodynamic profile and organ perfusion. Our aim was to study..

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Factor XI Inhibition With Heparin Reduces Clot Formation in Simulated Pediatric Extracorporeal Membrane Oxygenation

Abstract Extracorporeal membrane oxygenation (ECMO) supplies circulatory support and gas exchange to critically ill patients. Despite the use of systemic anticoagulation, blood exposure to ECMO surfaces causes thromboembolism complications. Inhibition..

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Ten things that nurses should know about ECMO

Abstract Venovenous extracorporeal membrane oxygenation (VVECMO) is a potent salvage therapy for ARDS patients who remain severely hypoxemic despite the use of more conventional treatments. In a study done in..

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Veno-arterial extracorporeal membrane oxygenation as a perioperative support to redo cardiac surgery for inoperable adult patients: a case series

Abstract Background The present article describes three cases of patients in cardiogenic shock (CS) with previous cardiac surgery that made them initially inoperable. Perioperative support with veno-arterial extracorporeal membrane oxygenation..

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Novel Left Ventricular Unloading Strategies in Patients on Peripheral Venoarterial Extracorporeal Membrane Oxygenation Support

Abstract The purpose of this study was to evaluate left ventricular (LV) unloading strategies in patients supported with peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). A retrospective review was conducted of..

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Long-term outcomes of patients supported with extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis

Abstract Background Extracorporeal membrane oxygenation (ECMO) is increasingly used to support patients with severe acute respiratory distress syndrome (ARDS). The impact of ECMO on long-term outcomes of patients with severe..

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Left-Ventricular Unloading With Impella During Refractory Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review and Meta-Analysis

Abstract Objectives:  Extracorporeal cardiopulmonary resuscitation (ECPR) is the implementation of venoarterial extracorporeal membrane oxygenation (VA-ECMO) during refractory cardiac arrest. The role of left-ventricular (LV) unloading with Impella in addition to..

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Blend to Limit Oxygen in ECMO: A RanDomised ControllEd Registry (BLENDER) Trial: Study Protocol and Statistical Analysis Plan

Abstract Introduction Critically ill patients supported with venoarterial  (VA ECMO) are at risk of developing severe arterial , which has been associated with increased mortality. Lower saturation targets in this population may..

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Neurologic Statistical Prognostication and Risk Assessment for Kids on Extracorporeal Membrane Oxygenation—Neuro SPARK

Abstract This study presents Neuro-SPARK, the first scoring system developed to assess the risk of neurologic injury in pediatric and neonatal patients on extracorporeal membrane oxygenation (ECMO). Using the extracorporeal..

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Early trends in ECMO mortality during the first quarters of 2019 and 2020: Could we have predicted the onset of…

Abstract Objective To compare mortality trends in patients requiring Extracorporeal Membrane Oxygenation (ECMO) support between the first quarters of 2019 and 2020 and determine whether these trends might have predicted..

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Use of Subclavian Extracorporeal Carbon Dioxide Removal for COVID-19 Acute Respiratory Distress Syndrome as a Bridge to Lung Transplantation

Abstract Severe acute hypercapnia is independently associated with increased adverse effects and intensive care unit mortality in mechanically ventilated patients. During the severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic,..

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Calcium Channel Blocker Overdose: What Role Does Extracorporeal Membrane Oxygenation Have in Support? A Systematic Review of the Literature

Abstract Extracorporeal membrane oxygenation (ECMO) has had increasing prevalence and indications in the last decade. Calcium channel blocker overdose (CCBOD) can lead to significant cardiopulmonary dysfunction and has also increased..

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The impact of extracorporeal membrane oxygenation on antifungal pharmacokinetics: A systematic review

Abstract Background and Objective The use of extracorporeal membrane oxygenation (ECMO) as a cardiocirculatory or respiratory support has tremendously increased in critically ill patients. In the setting of ECMO support,..

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Methemoglobinemia: A Case Study During ECMO

Abstract Methemoglobinemia is a rare blood disorder that can have severe consequences if not promptly diagnosed and treated. In this article, we will explore a real-life case study of a..

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Survival and Long-Term Functional Status of COVID-19 Patients Requiring Prolonged ECMO Support

Abstract Rationale Severe cases of acute respiratory distress syndrome (ARDS) may require prolonged (>28 days) extracorporeal membrane oxygenation (ECMO). In non-resolving disease, recovery is uncertain and lung transplant may be..

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Successful Prehospital Extracorporeal Cardiopulmonary Resuscitation: A Comprehensive Case Report and Analysis of the Current Experience and Knowledge

Abstract This case report describes a prehospital extracorporeal cardiopulmonary resuscitation (ECPR) in a female patient who suffered a sudden cardiac arrest while shopping in a supermarket. The success of this..

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Balloon atrial septostomy versus left atrial cannulation for left heart decompression in children with dilated cardiomyopathy and myocarditis on extracorporeal…

Abstract Introduction In children with myocarditis or dilated cardiomyopathy (DCM) on extracorporeal membrane oxygenation (ECMO) for cardiogenic shock, it is often necessary to decompress the left heart to minimize distension..

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State of the art: Monitoring of the respiratory system during veno-venous extracorporeal membrane oxygenation

Abstract Monitoring the patient receiving veno-venous extracorporeal membrane oxygenation (VV ECMO) is challenging due to the complex physiological interplay between native and membrane lung. Understanding these interactions is essential to..

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Extracorporeal membrane oxygenation in diabetic ketoacidosis-related cardiac and respiratory failure

Abstract Introduction: Diabetic ketoacidosis (DKA) is a common clinical problem. When patients develop severe shock and/or respiratory failure, extracorporeal membrane oxygenation (ECMO) may be considered. This case series describes the..

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Oxygenation During Venoarterial Extracorporeal Membrane Oxygenation: Physiology, Current Evidence, and a Pragmatic Approach to Oxygen Titration

Abstract OBJECTIVES:  This review aims to: 1) identify the key circuit and patient factors affecting systemic oxygenation, 2) summarize the literature reporting the association between hyperoxia and patient outcomes, and..

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Left Ventricular Unloading With Impella Versus IABP in Patients With VA-ECMO: A Systematic Review and Meta-Analysis

Abstract Venoarterial extracorporeal membrane oxygenation (VA-ECMO) use for circulatory support in cardiogenic shock results in increased left ventricular (LV) afterload. The use of concomitant Impella or intra-aortic balloon pump (IABP)..

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Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: 10-year experience in a metropolitan cardiac arrest centre in Milan, Italy

Abstract Introduction Growing evidence supports  cardiopulmonary resuscitation (ECPR) for refractory out-of-hospital cardiac arrest (OHCA) patients, especially in experienced centres. We present characteristics, , and outcomes of patients treated with ECPR in a..

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Pre-hospital ECPR in an Australian metropolitan setting: a single-arm feasibility assessment—The CPR, pre-hospital ECPR and early reperfusion (CHEER3) study

Abstract Introduction Survival from refractory out of hospital cardiac arrest (OHCA) without timely return of spontaneous circulation (ROSC) utilising conventional advanced cardiac life support (ACLS) therapies is dismal. CHEER3 was..

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Predictors of thrombosis during VV ECMO: an analysis of 9809 patients from the ELSO registry

Abstract Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a life-saving therapy for critically ill patients, but it carries an increased risk of thrombosis due to blood interacting with non-physiological surfaces. While..

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