Tags Archives: donation after circulatory death (DCD)

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DCD Heart and Lung Explantation With TransMedics OCS Heart Recovery and EVLP Lung Perfusion

I. PRE-PROCUREMENT PREPARATION (DCD CONTEXT)   1. Donor Selection and Planning •Confirm controlled DCD donor (Maastricht Category III). •Review: •Warm ischemic time (WIT) thresholds •Functional warm ischemia (fWIT) •Hemodynamics prior..

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Cardiac function recovery after 20-min hands-off using thoracoabdominal-normothermic regional perfusion

Abstract Background The increasing prevalence of end-stage heart failure coupled with limited donor organs creates a critical need for novel strategies in heart transplantation. Donation after circulatory death offers a..

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How I Do It: Donation After Circulatory Death With Normothermic Regional Perfusion in Small Babies

Abstract Background: The gold standard for treatment of patients with end-stage heart failure remains . Time spent on the active waiting list, notably for  patients, contributes to alarmingly high mortality. Donation after..

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The Evolving Role of Extracorporeal In Situ Perfusion Technology in Organ Donor Recovery with Donation After Circulatory Determination of Death…

Abstract The need for organs suitable for transplantation has continued to rise as need outweighs availability. Increased demand has driven innovation in the field. Over the past ten years, donation..

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Aortic Balloon Occlusion in Circulatory Determination of Death Donors Undergoing Abdominal Normothermic Regional Perfusion?

Abstract Normothermic regional perfusion (NRP) is a strategy of postmortem reperfusion with warm oxygenated blood of a portion of the body applied in donors undergoing circulatory determination of death (DCDDs)...

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On-Table Reanimation of a Pediatric Heart from Donation after Circulatory Death

Abstract Cardiac allotransplantation is warranted in children with end-stage heart failure or irreparable congenital heart disease. A dearth of organs for transplantation has contributed to long wait-list times and resultant..

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Direct procurement with machine perfusion and normothermic regional perfusion in donation after circulatory death heart transplantation

Abstract Background Donation after circulatory death (DCD) heart transplants have increased in the United States with direct procurement with machine perfusion (DPP) and thoracoabdominal normothermic regional perfusion (TA-NRP) techniques. There..

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The current landscape of in situ and ex situ machine perfusion utilization for liver grafts from cardiac donation after circulatory…

Abstract Donation after circulatory death (DCD) is driving the increase in deceased organ donors in the United States. Normothermic regional perfusion (NRP) and ex situ machine perfusion (es-MP) have been..

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Perfusión regional normotérmica (PRN) para la obtención de órganos.

Perfusión regional normotérmica (PRN) para la obtención de órganos en donación en asistolia controlada.   Ponente: Dr. Juan Blanco (España) Enfermero. Máster y Posgrado en Técnicas de perfusión y oxigenación..

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Brief hypothermic oxygenated perfusion provides cardioprotection in a pig model of donation after circulatory death

Abstract OBJECTIVES Donation after circulatory death provides excellent patient outcomes in heart transplantation; however, warm ischaemic graft damage remains a concern. We have reported that a brief period of hypothermic..

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Clinical Outcomes With Normothermic Pulsatile Organ Perfusion in Heart Transplantation: A Report From the OCS Heart Perfusion Registry

Abstract BACKGROUND: A preservation system, the Organ Care System (OCS; TransMedics) uses normothermic pulsatile perfusion during organ transport for heart transplantation. This system has demonstrated favorable outcomes in hearts recovered..

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Normothermic Regional Perfusion in Controlled Donation After the Circulatory Determination of Death: Understanding Where the Benefit Lies

Abstract Controlled donation after the circulatory determination of death (cDCDD) has emerged as a strategy to increase the availability of organs for clinical use. Traditionally, organs from cDCDD donors have..

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Extracorporeal lung perfusion and donation EVLPD in donation after circulatory death DCD

Extracorporeal lung perfusion and donation (EVLPD) in donation after circulatory death (DCD) patients is a groundbreaking advancement in organ transplantation, and Professor Sam Zeraatiannejaddavani, a world-renowned surgeon, has been at..

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Surgical Technique of Donation after Circulatory Death using Normothermic Regional Perfusion

Abstract Heart transplantation (HT) is the gold standard treatment of end-stage heart disease. Waitlist mortality remains high due to a shortage of available donor organs. Donation after circulatory death (DCD)..

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The potential benefits of monitoring oxygen delivery in relation to O2ERi and VCO2 during normothermic regional perfusion in DCD donors

As the field of organ transplantation continues to evolve, the use of Donation after Circulatory Death (DCD) donors has emerged as a critical method to expand the donor pool. However,..

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Outcomes of Multiorgan Heart Transplant Between Donation After Circulatory Death and Brain Death

Abstract There is insufficient data on the outcomes of donation after circulatory death (DCD) multiorgan transplant that includes heart. The primary objective of this study is to compare the overall..

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Tuscany Normothermic Regional Perfusion Mobile Teams for Controlled Donation After Circulatory Death

Abstract Introduction To facilitate the implementation of controlled donation after circulatory death (cDCD) programs even in hospitals not equipped with a local extracorporeal membrane oxygenation (ECMO) team, some countries have..

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Thoracoabdominal Normothermic Regional Perfusion Using Mobile Closed Extracorporeal Circuit in Circulatory Death Determination Heart Donors

Abstract Thoracoabdominal normothermic regional perfusion (TA-NRP) is increasingly implemented in donation after circulatory determination of death (DCD). Thoracoabdominal normothermic regional perfusion allows thoracic and abdominal organs to be perfused with..

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Heart transplantation using donation after circulatory death in the United States

Abstract Objectives Heart donation after circulatory death was recently reintroduced in the United States with hopes of increasing donor heart availability. We examined its national use and outcomes. Methods The..

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Successful Recovery of Cardiac Function Following 20 min of a No-touch Period in a Donation After Circulatory Death: A Case…

Abstract Background.  Withdrawal of life-sustaining therapy (WLST) performed in the circulatory determination of death (DCD) donors leads to cardiac arrest, challenging the utilization of the myocardium for transplantation. The rapid..

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Beating Heart Transplantation: How to Do It

Abstract Heart transplantation utilizing deceased after circulatory death (DCD) donors has expanded the donor pool through the use of ex vivo normothermic perfusion. Compared with brain death donation, the conventional..

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Normothermic Regional Perfusion is an Emerging Cost-Effective Alternative in Donation After Circulatory Death (DCD) in Heart Transplantation

Abstract In donation after circulatory death (DCD) organ transplantation, normothermic regional perfusion (NRP) restores oxygenated blood flow following cardiac arrest and reverses warm ischemia. Recently, NRP has also been used..

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Heart Transplantation From DCD Donors in Australia: Lessons Learned From the First 74 Cases

Abstract Heart transplantation from donation after circulatory death (DCD) donors has the potential to substantially increase overall heart transplant activity. The aim of this report is to review the first..

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Normothermic regional perfusion in DCD organ donors, a primer

Normothermic regional perfusion in DCD organ donors, a primer: first EuroELSO webinar on ECLS in donors undergoing determination of death according to circulatory criteria. Moderators: Marius Berman & Eduardo Miñambres..

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Use of Extracorporeal Membrane Oxygenation for Primary Graft Dysfunction After Cardiac Transplantation: Results of an A Priori Ventless Approach

Abstract Primary graft dysfunction (PGD) after cardiac transplantation is a devastating complication with increasing frequency lately in the setting of donation after circulatory death (DCD). Severe PGD is commonly treated..

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